All Outputs (122)

Assessment of motion of colonic contents in the human colon using MRI tagging (2017)
Journal Article

Background We have previously reported a non-invasive, semi-automated technique to assess motility of the wall of the ascending colon (AC) using Magnetic Resonance Imaging. This study investigated the feasibility of using a tagged MRI technique to vi... Read More about Assessment of motion of colonic contents in the human colon using MRI tagging.

Focal CA3 hippocampal subfield atrophy following LGI1 VGKC-complex antibody limbic encephalitis (2017)
Journal Article

© The Author (2017). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. Magnetic resonance imaging has linked chronic voltage-gated potassium channel (VGKC) complex antibody-mediated limbic encephalitis wi... Read More about Focal CA3 hippocampal subfield atrophy following LGI1 VGKC-complex antibody limbic encephalitis.

Functional neuroimaging predictors of self-reported psychotic symptoms in adolescents (2017)
Journal Article

OBJECTIVE: This study aimed to investigate the neural correlates of psychotic-like experiences in youth on measures of inhibitory control, reward anticipation and emotion processing. A secondary aim was to test whether these neuro-functional correlat... Read More about Functional neuroimaging predictors of self-reported psychotic symptoms in adolescents.

³¹P magnetization transfer magnetic resonance spectroscopy: assessing the activation induced change in cerebral ATP metabolic rates at 3 T (2017)
Journal Article

Purpose: In vivo ³¹P MRS magnetization transfer (MT) provides a direct measure of neuronal activity at the metabolic level. This work aims to use functional ³¹P MRS-MT to investigate the change in cerebral ATP metabolic rates in healthy adults upon r... Read More about ³¹P magnetization transfer magnetic resonance spectroscopy: assessing the activation induced change in cerebral ATP metabolic rates at 3 T.

Impact of a common genetic variation associated with putamen volume on neural mechanisms of ADHD (2017)
Journal Article

Objective: In a recent genome-wide association study of subcortical brain volumes, we have identified common genetic variation at rs945270 as having the strongest effect on putamen volume, a brain measure linked to familial risk for attentiondeficit/... Read More about Impact of a common genetic variation associated with putamen volume on neural mechanisms of ADHD.

ICNIRP statement on diagnostic devices using non-ionizing radiation: existing regulations and potential health risks (2017)
Journal Article

Use of non-ionizing radiation (NIR) for diagnostic purposes allows non-invasive assessment of the structure and function of the human body, and is widely employed in medical care. ICNIRP has published previous statements about the protection of patie... Read More about ICNIRP statement on diagnostic devices using non-ionizing radiation: existing regulations and potential health risks.

Abnormal task driven neural oscillations in multiple sclerosis: a visuomotor MEG study (2017)
Journal Article

Multiple sclerosis (MS) is a debilitating disease commonly attributed to degradation of white matter myelin. Symptoms include fatigue, as well as problems associated with vision and movement. Although areas of demyelination in white matter are observ... Read More about Abnormal task driven neural oscillations in multiple sclerosis: a visuomotor MEG study.

Relationships between cortical myeloarchitecture and electrophysiological networks (2016)
Journal Article

The human brain relies upon the dynamic formation and dissolution of a hierarchy of functional networks to support ongoing cognition. However, how functional connectivities underlying such networks are supported by cortical microstructure remains poo... Read More about Relationships between cortical myeloarchitecture and electrophysiological networks.

Quantitative analysis of the z-spectrum using a numerically simulated look-up table: application to the healthy human brain at 7T (2016)
Journal Article

Purpose: To develop a method that fits a multipool model to z-spectra acquired from non–steady state sequences, taking into account the effects of variations in T1 or B1 amplitude and the results estimating the parameters for a four-pool model to des... Read More about Quantitative analysis of the z-spectrum using a numerically simulated look-up table: application to the healthy human brain at 7T.

Colon Hypersensitivity to Distension, Rather Than Excessive Gas Production, Produces Carbohydrate-Related Symptoms in Individuals With Irritable Bowel Syndrome (2016)
Journal Article

Background & Aims: Poorly digested, fermentable carbohydrates may induce symptoms of irritable bowel syndrome (IBS), via unclear mechanisms. We performed a randomized trial with magnetic resonance imaging (MRI) analysis to investigate correlations be... Read More about Colon Hypersensitivity to Distension, Rather Than Excessive Gas Production, Produces Carbohydrate-Related Symptoms in Individuals With Irritable Bowel Syndrome.

Histological basis of laminar MRI patterns in high resolution images of fixed human auditory cortex (2016)
Journal Article

Functional magnetic resonance imaging (fMRI) studies of the auditory region of the temporal lobe would benefit from the availability of image contrast that allowed direct identification of the primary auditory cortex, as this region cannot be accurat... Read More about Histological basis of laminar MRI patterns in high resolution images of fixed human auditory cortex.

Field strength dependence of grey matter R2* on venous oxygenation (2016)
Journal Article

The relationship between venous blood oxygenation and change in transverse relaxation rate (?R2 *) plays a key role in calibrated BOLD fMRI. This relationship, defined by the parameter ?, has previously been determined using theoretical simulations a... Read More about Field strength dependence of grey matter R2* on venous oxygenation.

Increased liver fat and glycogen stores after consumption of high versus low glycaemic index food: a randomized crossover study (2016)
Journal Article

Aim: To investigate the acute and longer-term effects of low (LGI) versus high glycaemic index (HGI) diets on hepatic fat and glycogen accumulation and related blood measures in healthy volunteers. Methods: Eight healthy men (age 20.1 � 0.4 years,... Read More about Increased liver fat and glycogen stores after consumption of high versus low glycaemic index food: a randomized crossover study.

Prior Consumption of a Fat Meal in Healthy Adults Modulates the Brain's Response to Fat (2016)
Journal Article

Background: Consumption of fat is regulated by reward and homeostatic pathways, but no studies have examined the role of the intake of a high fat meal (HFM) on subsequent brain activation to oral stimuli. Objective: We evaluated how prior consumptio... Read More about Prior Consumption of a Fat Meal in Healthy Adults Modulates the Brain's Response to Fat.

Comparison of pulsed three-dimensional CEST acquisition schemes at 7 tesla: steady state versus pseudosteady state (2016)
Journal Article

Purpose: To compare two pulsed, volumetric chemical exchange saturation transfer (CEST) acquisition schemes: steady state (SS) and pseudosteady state (PS) for the same brain coverage, spatial/spectral resolution and scan time. Methods: Both schemes... Read More about Comparison of pulsed three-dimensional CEST acquisition schemes at 7 tesla: steady state versus pseudosteady state.

Polygenic risk of psychosis and ventral striatal activation during reward processing in healthy adolescents (2016)
Journal Article

Importance: Psychotic disorders are characterized by attenuated activity in the brain’s valuation system in key reward processing areas, such as the ventral striatum (VS), as measured with functional magnetic resonance imaging. Objective: To examine... Read More about Polygenic risk of psychosis and ventral striatal activation during reward processing in healthy adolescents.

Prediction of alcohol drinking in adolescents: Personality-traits, behavior, brain responses, and genetic variations in the context of reward sensitivity (2016)
Journal Article

Adolescence is a time that can set the course of alcohol abuse later in life. Sensitivity to reward on multiple levels is a major factor in this development. We examined 736 adolescents from the IMAGEN longitudinal study for alcohol drinking during e... Read More about Prediction of alcohol drinking in adolescents: Personality-traits, behavior, brain responses, and genetic variations in the context of reward sensitivity.

A comparison of phase imaging and quantitative susceptibility mapping in the imaging of multiple sclerosis lesions at ultrahigh field (2016)
Journal Article

Objective The aim of this study was to compare the use of high-resolution phase and QSM images acquired at ultra-high field in the investigation of multiple sclerosis (MS) lesions with peripheral rings, and to discuss their usefulness for drawing... Read More about A comparison of phase imaging and quantitative susceptibility mapping in the imaging of multiple sclerosis lesions at ultrahigh field.

Corticotrophin releasing factor increases ascending colon volume after a fructose test meal in healthy humans: a randomised control trial (2016)
Journal Article

Background: Poorly absorbed, fermentable carbohydrates can provoke irritable bowel syndrome (IBS) symptoms by escaping absorption in the small bowel and being rapidly fermented in the colon in some susceptible subjects. IBS patients are often anxious... Read More about Corticotrophin releasing factor increases ascending colon volume after a fructose test meal in healthy humans: a randomised control trial.

Structural brain correlates of adolescent resilience (2016)
Journal Article

Background Despite calls for integration of neurobiological methods into research on youth resilience (high competence despite high adversity), we know little about structural brain correlates of resilient functioning. The aim of the current study... Read More about Structural brain correlates of adolescent resilience.