Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patients

Izquierdo, Elisa; Proszek, Paula; Pericoli, Giulia; Temelso, Sara; Clarke, Matthew; Carvalho, Diana M; Mackay, Alan; Marshall, Lynley V; Carceller, Fernando; Hargrave, Darren; Lannering, Birgitta; Pavelka, Zdenek; Bailey, Simon; Entz-Werle, Natacha; Grill, Jacques; Vassal, Gilles; Rodriguez, Daniel; Morgan, Paul S; Jaspan, Tim; Mastronuzzi, Angela; Vinci, Mara; Hubank, Michael; Jones, Chris

doi:10.1093/noajnl/vdab013

All Outputs (5)

Oxygen-enhanced MRI assessment of tumour hypoxia in head and neck cancer is feasible and well tolerated in the clinical setting (2024)
Journal Article

Background: Tumour hypoxia is a recognised cause of radiotherapy treatment resistance in head and neck squamous cell carcinoma (HNSCC). Current positron emission tomography-based hypoxia imaging techniques are not routinely available in many centres.... Read More about Oxygen-enhanced MRI assessment of tumour hypoxia in head and neck cancer is feasible and well tolerated in the clinical setting.

A resource for development and comparison of multimodal brain 3T MRI harmonisation approaches (2023)
Journal Article

Despite the huge potential of magnetic resonance imaging (MRI) in mapping and exploring the brain, MRI measures can often be limited in their consistency, reproducibility and accuracy which subsequently restricts their quantifiability. Nuisance nonbi... Read More about A resource for development and comparison of multimodal brain 3T MRI harmonisation approaches.

T1 based oxygen-enhanced MRI in tumours; a scoping review of current research (2023)
Journal Article

OBJECTIVE: Oxygen-enhanced MRI (OE-MRI) or tissue oxygen-level dependent (TOLD) MRI is an imaging technique under investigation for its ability to quantify and map oxygen distributions within tumours. The aim of this study was to identify and charact... Read More about T1 based oxygen-enhanced MRI in tumours; a scoping review of current research.

Dynamic susceptibility-contrast magnetic resonance imaging with contrast agent leakage correction aids in predicting grade in pediatric brain tumours: a multicenter study (2022)
Journal Article

Background Relative cerebral blood volume (rCBV) measured using dynamic susceptibility-contrast MRI can differentiate between low- and high-grade pediatric brain tumors. Multicenter studies are required for translation into clinical practice. Obj... Read More about Dynamic susceptibility-contrast magnetic resonance imaging with contrast agent leakage correction aids in predicting grade in pediatric brain tumours: a multicenter study.

Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patients (2021)
Journal Article

Background The use of liquid biopsy is of potential high importance for children with high grade (HGG) and diffuse midline gliomas (DMG), particularly where surgical procedures are limited, and invasive biopsy sampling not without risk. To date, how... Read More about Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patients.