All Outputs (80)

ASSERT (Acute Sacral inSufficiEncy fractuRe augmenTation): randomised controlled, feasibility trial in older people (2022)
Journal Article

Objective To determine the feasibility of designing and conducting a definitive trial to evaluate the effectiveness of sacral fracture fixation compared with non-surgical management among older people admitted with a lateral compression pelvic fragil... Read More about ASSERT (Acute Sacral inSufficiEncy fractuRe augmenTation): randomised controlled, feasibility trial in older people.

Treatment of Hidradenitis Suppurativa Evaluation Study (THESEUS): protocol for a prospective cohort study (2022)
Journal Article

Background Hidradenitis suppurativa (HS) is a chronic, painful, inflammatory skin disease with estimates of prevalence in the European population of 1%–2%. Despite being a relatively common condition, the evidence base for management of HS is limited... Read More about Treatment of Hidradenitis Suppurativa Evaluation Study (THESEUS): protocol for a prospective cohort study.

The COVID-19 pandemic has highlighted the need to invest in care home research infrastructure (2022)
Journal Article

The COVID-19 pandemic resulted in catastrophic levels of morbidity and mortality for care home residents. Despite this, research platforms for COVID-19 in care homes arrived late in the pandemic compared with other care settings. The Prophylactic The... Read More about The COVID-19 pandemic has highlighted the need to invest in care home research infrastructure.

A multidomain decision support tool to prevent falls in older people: the FinCH cluster RCT (2022)
Journal Article

Background Falls in care home residents are common, unpleasant, costly and difficult to prevent. Objectives The objectives were to evaluate the clinical effectiveness and cost-effectiveness of the Guide to Action for falls prevention in Care Hom... Read More about A multidomain decision support tool to prevent falls in older people: the FinCH cluster RCT.

Working in partnership with the patient community to develop outline trial designs in CF (2021)
Journal Article

In a collaboration between health professionals and the patient community, we previously identified the Top 10 priorities for clinical research in CF [ [1] ]. Here, we have used a similar approach to explore four of these priorities further and sugge... Read More about Working in partnership with the patient community to develop outline trial designs in CF.

Multifactorial falls prevention programme compared with usual care in UK care homes for older people: Multicentre cluster randomised controlled trial with economic evaluation (2021)
Journal Article

Objectives To determine the clinical and cost effectiveness of a multifactorial fall prevention programme compared with usual care in long term care homes. Design Multicentre, parallel, cluster randomised controlled trial. Setting Long term care home... Read More about Multifactorial falls prevention programme compared with usual care in UK care homes for older people: Multicentre cluster randomised controlled trial with economic evaluation.

Primary care management of hidradenitis suppurativa: a cross-sectional survey of UK GPs (2021)
Journal Article

Background Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease that causes painful discharging nodules and skin tunnels. HS has associations with several systemic diseases, including cardiovascular disease (CVD), anxiety, and depress... Read More about Primary care management of hidradenitis suppurativa: a cross-sectional survey of UK GPs.

Exploring the challenges of accessing medication for patients with cystic fibrosis (2021)
Journal Article

Reducing treatment burden in cystic fibrosis (CF) is the top research priority for patients and clinicians. Difficulty accessing medication is one aspect of treatment burden. We investigated this with an online survey available globally for patients... Read More about Exploring the challenges of accessing medication for patients with cystic fibrosis.

What can we learn from the experiences and expectations of patients on growing waiting lists for planned care in the COVID-19 pandemic? (2021)
Journal Article

COVID-19 has compounded a growing waiting list problem, with over 4.5 million patients now waiting for planned elective care in the UK. Views of patients on waiting lists are rarely considered in prioritization. Our primary aim was to understand how... Read More about What can we learn from the experiences and expectations of patients on growing waiting lists for planned care in the COVID-19 pandemic?.

Protocol for surgical and non-surgical treatment for metacarpal shaft fractures in adults: an observational feasibility study (2021)
Journal Article

Introduction Metacarpal shaft fractures (MSF) are common traumatic hand injuries that usually affect young people of working age. They place a significant burden on healthcare resources and society, however there is a lack of evidence to guide thei... Read More about Protocol for surgical and non-surgical treatment for metacarpal shaft fractures in adults: an observational feasibility study.

Learning from a successful process evaluation in care homes (2021)
Journal Article

Introduction process evaluations (PE) are increasingly used in parallel with randomised controlled trials (RCT) to inform the implementation of complex health interventions. This paper explores the learning accrued from conducting a PE within the Fa... Read More about Learning from a successful process evaluation in care homes.

Clinical Utility of small bowel ultrasound assessment of Crohn’s Disease in Adults: A systematic scoping review (2021)
Journal Article

Background: Ultrasound is an alternative to Magnetic Resonance Enterography, and has the potential to significantly reduce waiting times, expedite clinical decision making and improve patient experience. Point of care ultrasound is an advantage of th... Read More about Clinical Utility of small bowel ultrasound assessment of Crohn’s Disease in Adults: A systematic scoping review.

Thematic synthesis of the experiences of people with hidradenitis suppurativa: a systematic review* (2021)
Journal Article

Background: Although hidradenitis suppurativa (HS) is known to affect quality of life, little summative knowledge exists on how HS impacts people living with the condition. Objectives: To synthesize experiences of people with HS within published qual... Read More about Thematic synthesis of the experiences of people with hidradenitis suppurativa: a systematic review*.

Cognitive assessment in multiple sclerosis clinical care: A qualitative evaluation of stakeholder perceptions and preferences (2021)
Journal Article

There is a growing consensus that cognitive assessments should form part of routine clinical care in Multiple Sclerosis (MS). However, what remains unclear is which assessments are preferred by “stakeholders” (including people with MS, family members... Read More about Cognitive assessment in multiple sclerosis clinical care: A qualitative evaluation of stakeholder perceptions and preferences.

Supporting self-care for eczema: protocol for two randomised controlled trials of ECO (Eczema Care Online) interventions for young people and parents/carers (2021)
Journal Article

Introduction Eczema care requires management of triggers and various treatments. We developed two online behavioural interventions to support eczema care called ECO (Eczema Care Online) for young people and ECO for families. This protocol describes t... Read More about Supporting self-care for eczema: protocol for two randomised controlled trials of ECO (Eczema Care Online) interventions for young people and parents/carers.

Developing a core outcome set for hand fractures and joint injuries in adults: a systematic review (2021)
Journal Article

© The Author(s) 2021. This study identifies the treatment outcome domains used in recently published studies on the treatment of hand fractures and joint injuries with the aim to inform development of a core outcome set. Seven databases were searched... Read More about Developing a core outcome set for hand fractures and joint injuries in adults: a systematic review.

Home-based narrowband UVB, topical corticosteroid or combination for children and adults with vitiligo: HI-light vitiligo three-arm RCT (2020)
Journal Article

Background: Systematic reviews suggest that narrowband ultraviolet B light combined with treatments such as topical corticosteroids may be more effective than monotherapy for vitiligo. Objective: To explore the clinical effectiveness and cost-effecti... Read More about Home-based narrowband UVB, topical corticosteroid or combination for children and adults with vitiligo: HI-light vitiligo three-arm RCT.

Defining stable glaucoma: a Delphi consensus survey of UK optometrists with a specialist interest in Glaucoma (2020)
Journal Article

Background Increasing demand on hospital services has led to the development of alternative community-based services, often run by optometrists for monitoring ‘stable’ and low-risk glaucoma patients. Methods An online Delphi exercise was underta... Read More about Defining stable glaucoma: a Delphi consensus survey of UK optometrists with a specialist interest in Glaucoma.

Surgical fixation compared with cast immobilisation for adults with a bicortical fracture of the scaphoid waist: the SWIFFT RCT (2020)
Journal Article

Background: Scaphoid fractures account for 90% of carpal fractures and occur predominantly in young men. Immediate surgical fixation of this fracture has increased. Objective: To compare the clinical effectiveness and cost-effectiveness of surgical f... Read More about Surgical fixation compared with cast immobilisation for adults with a bicortical fracture of the scaphoid waist: the SWIFFT RCT.

An interview study of the experiences of cellulitis diagnosis amongst health care professionals (2020)
Journal Article

Objectives: To explore healthcare professionals (HCPs) experiences and challenges in diagnosing suspected lower limb cellulitis. Setting: UK nationwide. Participants: 20 qualified HCPs, who had a minimum of 2 years clinical experience as an HCP... Read More about An interview study of the experiences of cellulitis diagnosis amongst health care professionals.