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Developing a core outcome set for hand fractures and joint injuries in adults: a systematic review

Deshmukh, Sandeep Rajiv; Mousoulis, Christos; Marson, Ben A.; Grindlay, Douglas; Karantana, Alexia; the Core Outcome Set for Hand Fractures and Joint Injuries in Adults Group; Leighton, Paul; Montgomery, Alan A.

Developing a core outcome set for hand fractures and joint injuries in adults: a systematic review Thumbnail


Authors

Sandeep Rajiv Deshmukh

Christos Mousoulis

BEN MARSON BEN.MARSON3@NOTTINGHAM.AC.UK
Clinical Associate Professorin Paediatric Orthopaedic Surgery

Douglas Grindlay

ALEXIA KARANTANA ALEXIA.KARANTANA@NOTTINGHAM.AC.UK
Clinical Associate Professor in Hand Surgery

the Core Outcome Set for Hand Fractures and Joint Injuries in Adults Group

PAUL LEIGHTON PAUL.LEIGHTON@NOTTINGHAM.AC.UK
Associate Professor of Applied Health Services Research

ALAN MONTGOMERY ALAN.MONTGOMERY@NOTTINGHAM.AC.UK
Director Nottingham Clinical Trials Unit



Abstract

© The Author(s) 2021. This study identifies the treatment outcome domains used in recently published studies on the treatment of hand fractures and joint injuries with the aim to inform development of a core outcome set. Seven databases were searched from January 2014 to March 2019 for randomized and quasi-randomized studies and large prospective observational studies. We identified 1777 verbatim outcomes in 160 eligible studies. From the verbatim outcomes we distinguished 639 unique outcomes, which we categorized into 74 outcome domains based on the World Health Organization International Classification of Functioning, Disability, and Health framework. The primary outcome was appropriately identified in only 65% (72/110) of randomized and quasi-randomized controlled trials. Of the 72 studies with a primary outcome identified, 74% (53/72) had an appropriate power calculation. The vast heterogeneity in outcome selection across studies highlights the need for a core outcome set of what outcomes to measure in future clinical research on hand fractures and joint injuries.

Journal Article Type Article
Acceptance Date Dec 6, 2020
Online Publication Date Jan 24, 2021
Publication Date 2021-06
Deposit Date Jan 29, 2021
Publicly Available Date Jan 29, 2021
Journal Journal of Hand Surgery: European Volume
Print ISSN 1753-1934
Electronic ISSN 2043-6289
Publisher SAGE Publications
Peer Reviewed Peer Reviewed
Volume 46
Issue 5
Pages 488-495
DOI https://doi.org/10.1177/1753193420983719
Keywords Hand fractures, Joint injuries, Core outcome set, Treatment outcomes, Systematic review.
Public URL https://nottingham-repository.worktribe.com/output/5274345
Publisher URL https://journals.sagepub.com/doi/full/10.1177/1753193420983719
Additional Information See manuscript for a full list of authors in the Core Outcome Set for Hand Fractures and Joint Injuries in Adults Group.

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