Simulating the Hydrodynamic Conditions of the Human Ascending Colon: A Digital Twin of the Dynamic Colon Model

Schütt, Michael; O’Farrell, Connor; Stamatopoulos, Konstantinos; Hoad, Caroline L.; Marciani, Luca; Sulaiman, Sarah; Simmons, Mark J. H.; Batchelor, Hannah K.; Alexiadis, Alessio

doi:10.3390/pharmaceutics14010184

All Outputs (6)

Correction: Schütt et al. Simulating the Hydrodynamic Conditions of the Human Ascending Colon: A Digital Twin of the Dynamic Colon Model. (Pharmaceutics (2022), (14), (184)) (2022)
Journal Article

In the original publication [1], there was a mistake in Figure 6 when published. The experimental data points in the upper diagram were missing. The corrected Figure 6 appears below.

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The performance of solid oral dosage forms targeting the colon is typically evaluated using standardised pharmacopeial dissolution apparatuses. However, these fail to replicate colonic hydrodynamics. This study develops a digital twin of the Dynamic... Read More about Simulating the Hydrodynamic Conditions of the Human Ascending Colon: A Digital Twin of the Dynamic Colon Model.