All Outputs (5)

Peptide hydrogels — a tissue engineering strategy for the prevention of oesophageal strictures (2017)
Journal Article

Endoscopic treatment of Barrett’s oesophagus often leads to further damage of healthy tissue causing fibrotic tissue formation termed as strictures. This study shows that synthetic, self-assembling peptide hydrogels (PeptiGelDesign) support the activ... Read More about Peptide hydrogels — a tissue engineering strategy for the prevention of oesophageal strictures.

Translational considerations in injectable cell-based therapeutics for neurological applications: concepts, progress and challenges (2017)
Journal Article

Significant progress has been made during the past decade towards the clinical adoption of cell- based therapeutics. However, existing cell delivery approaches have shown limited success, with numerous studies showing fewer than 5% of injected cells... Read More about Translational considerations in injectable cell-based therapeutics for neurological applications: concepts, progress and challenges.

Decellularized bone extracellular matrix and human dental pulp stem cells as a construct for bone regeneration (2017)
Journal Article

Dental pulp tissue represents a source of mesenchymal stem cells (MSCs) that have a strong differentiation potential towards the osteogenic lineage. The objective of the current study was to examine in vitro osteogenic induction of dental pulp stem c... Read More about Decellularized bone extracellular matrix and human dental pulp stem cells as a construct for bone regeneration.

Macrophage phenotype in response to ECM bioscaffolds (2017)
Journal Article

Macrophage presence and phenotype are critical determinants of the healing response following injury. Downregulation of the pro-inflammatory macrophage phenotype has been associated with the therapeutic use of bioscaffolds composed of extracellular... Read More about Macrophage phenotype in response to ECM bioscaffolds.

Surface modification of PdlLGA microspheres with gelatine methacrylate: evaluation of adsorption, entrapment, and oxygen plasma treatment approaches (2017)
Journal Article

Injectable poly (dl-lactic-co-glycolic acid) (PdlLGA) microspheres are promising candidates as biodegradable controlled release carriers for drug and cell delivery applications; however, they have limited functional groups on the surface to enable de... Read More about Surface modification of PdlLGA microspheres with gelatine methacrylate: evaluation of adsorption, entrapment, and oxygen plasma treatment approaches.