All Outputs (25)

Ethical challenges experienced by veterinary practitioners in relation to adverse events: Insights from a qualitative study (2023)
Journal Article

Background Understanding ethical challenges experienced in relation to adverse events is necessary to inform strategies that optimise patient safety and practitioner wellbeing. Methods A qualitative exploration of UK veterinary practitioners’ ex... Read More about Ethical challenges experienced by veterinary practitioners in relation to adverse events: Insights from a qualitative study.

Robenacoxib versus meloxicam following ovariohysterectomy in cats: A randomised, prospective clinical trial involving owner‐based assessment of pain (2023)
Journal Article

Background Injectable non-steroidal anti-inflammatory drugs (NSAIDs) are commonly prescribed to queens undergoing ovariohysterectomy (OVH), but the requirement for postoperative administration is unclear and practices vary. Existing studies assessin... Read More about Robenacoxib versus meloxicam following ovariohysterectomy in cats: A randomised, prospective clinical trial involving owner‐based assessment of pain.

A case of carrier gas confusion: Unintentional use of carbogen (2022)
Journal Article

Alfaxalone population pharmacokinetics in the rat: Model application for pharmacokinetic and pharmacodynamic design in inbred and outbred strains and sexes (2022)
Journal Article

The translation of new injectable anaesthetic drugs from rodent to humans remains slow, despite the realisation that reliance on the volatile agents is unsustainable from an environmental perspective. The aim of this study was to investigate the infl... Read More about Alfaxalone population pharmacokinetics in the rat: Model application for pharmacokinetic and pharmacodynamic design in inbred and outbred strains and sexes.

Vitamin D status in chimpanzees in human care: a Europe wide study (2022)
Journal Article

While vitamin D deficiency is a public health concern in humans, comparatively little is known about vitamin D levels in non-human primates. Vitamin D plays a crucial role in overall health and its deficiency is associated with a range of disorders,... Read More about Vitamin D status in chimpanzees in human care: a Europe wide study.

“We’re gonna end up scared to do anything”: a qualitative exploration of how complaints are experienced by UK veterinary practitioners (2022)
Journal Article

Background: UK veterinary practitioners are reported to be fearful of client complaints but their experiences have not been formally captured. Understanding how complaints impact veterinary practitioners is key to mitigating detrimental consequences.... Read More about “We’re gonna end up scared to do anything”: a qualitative exploration of how complaints are experienced by UK veterinary practitioners.

Sevoflurane or isoflurane anaesthesia? A prospective, randomised blinded clinical trial in horses undergoing elective surgery (2021)
Journal Article

Background: Isoflurane is the only volatile anaesthetic agent licensed for equine use in the United Kingdom, but sevoflurane is also commonly used. The two agents have rarely been compared for use in clinical elective surgery. Methods: This single ce... Read More about Sevoflurane or isoflurane anaesthesia? A prospective, randomised blinded clinical trial in horses undergoing elective surgery.

Evaluation of the agreement of two oscillometric blood pressure devices with invasive blood pressure in anaesthetized chimpanzees (Pan troglodytes) (2021)
Journal Article

Objective: To evaluate the agreement of two noninvasive blood pressure devices: a human device with the cuff placed on the wrist (Omron R1) and a veterinary device with the cuff placed on the upper brachium (Surgivet Advisor Vital Signs Monitor) with... Read More about Evaluation of the agreement of two oscillometric blood pressure devices with invasive blood pressure in anaesthetized chimpanzees (Pan troglodytes).

Assessing the Educational Value of a Zoo Placement for Veterinary Students: A Report on Student Feedback and Perceptions (2021)
Journal Article

Zoological medicine is an expanding field with limited practical training opportunities for veterinary students. Those training programs that do exist require significant financial and resource investment by both veterinary schools and the zoological... Read More about Assessing the Educational Value of a Zoo Placement for Veterinary Students: A Report on Student Feedback and Perceptions.

Discovery of os cordis in the cardiac skeleton of chimpanzees (Pan troglodytes) (2020)
Journal Article

© 2020, The Author(s). Cardiovascular diseases, especially idiopathic myocardial fibrosis, is one of the most significant causes of morbidity and mortality in captive great apes. This study compared the structure and morphology of 16 hearts from chim... Read More about Discovery of os cordis in the cardiac skeleton of chimpanzees (Pan troglodytes).

Comparison of 25?hydroxyvitamin D concentration in chimpanzee dried blood spots and serum (2020)
Journal Article

Background Dried blood spots (DBS) are used in human medicine to measure total 25‐hydroxyvitamin D (25‐OHD) in the blood. However, this easy and affordable sampling technique has not been evaluated in primates to measure vitamin D concentrations.... Read More about Comparison of 25?hydroxyvitamin D concentration in chimpanzee dried blood spots and serum.

Comparison of the effects of buprenorphine and methadone in combination with medetomidine followed by intramuscular alfaxalone for anaesthesia of cats undergoing ovariohysterectomy (2019)
Journal Article

Objectives The aim of this study was to compare quality of anaesthesia and analgesia between methadone and buprenorphine in combination with medetomidine after induction with intramuscular (IM) alfaxalone in cats undergoing ovariohysterectomy.... Read More about Comparison of the effects of buprenorphine and methadone in combination with medetomidine followed by intramuscular alfaxalone for anaesthesia of cats undergoing ovariohysterectomy.

A clinical study to evaluate the cardiopulmonary characteristics of two different anaesthetic protocols (tiletamine/zolazepam +/- medetomidine) and to evaluate their suitability for the immobilisation of healthy chimpanzees (2018)
Journal Article

Objective: To characterise the cardiopulmonary characteristics of two different anaesthetic protocols (tiletamine/zolazepam +/- medetomidine) and their suitability for the immobilisation of healthy chimpanzees undergoing cardiac assessment. Study de... Read More about A clinical study to evaluate the cardiopulmonary characteristics of two different anaesthetic protocols (tiletamine/zolazepam +/- medetomidine) and to evaluate their suitability for the immobilisation of healthy chimpanzees.

A retrospective review of great ape cardiovascular disease epidemiology and pathology (2018)
Journal Article

Cardiovascular disease is associated with significant mortality in zoo-housed great apes and yet little is know about its epidemiology and aetiopathogenesis, and therefore its diagnosis, treatment and prevention. In this retrospective study, the fre... Read More about A retrospective review of great ape cardiovascular disease epidemiology and pathology.

Gainfully employing descending controls in acute and chronic pain management (2018)
Journal Article

Specific primary afferent fibres termed nociceptors are responsible for transmitting nociceptive information. Centrally the axonal terminals of these fibres synapse with secondary projection neurones in the spinal dorsal horn to transmit nociceptive... Read More about Gainfully employing descending controls in acute and chronic pain management.

A retrospective review of western lowland gorilla (gorilla, gorilla, gorilla) mortality in European zoological collections between 2004 and 2014 (2017)
Journal Article

An understanding of the main causes of mortality among captive gorillas is imperative to promoting their optimal care, health, and welfare. A retrospective observational review of mortality among the European zoo–housed western lowland gorilla (Goril... Read More about A retrospective review of western lowland gorilla (gorilla, gorilla, gorilla) mortality in European zoological collections between 2004 and 2014.

Safety culture: the Nottingham Veterinary Safety Culture Survey (NVSCS) (2017)
Journal Article

Safety culture is a vital concept in human healthcare because of its influence on staff behaviours in relation to patient safety. Understanding safety culture is essential to ensure the acceptance and sustainability of changes, such as the introducti... Read More about Safety culture: the Nottingham Veterinary Safety Culture Survey (NVSCS).

Clinical comparison of alfaxalone, ketamine and propofol following medetomidine and methadone in dogs (2017)
Journal Article

Objective To compare the clinical effects of alfaxalone, ketamine and propofol in dogs following premedication with medetomidine and methadone. Study design Prospective, ‘blinded’ and randomized clinical study. Animals A total of 75 ma... Read More about Clinical comparison of alfaxalone, ketamine and propofol following medetomidine and methadone in dogs.

A clinical evaluation of the pharmacokinetics and pharmacodynamics of intravenous alfaxalone in cyclodextrin in male and female rats following a loading dose and constant rate infusion (2017)
Journal Article

Objective: To characterise, as a clinical study, the pharmacokinetics and pharmacodynamics and describe the hypnotic effect of the neurosteroid alfaxalone (3?-hydroxy-5 ?-pregnane-11, 20-dione) formulated with 2-hydroxypropyl-?-cyclodextrin in male a... Read More about A clinical evaluation of the pharmacokinetics and pharmacodynamics of intravenous alfaxalone in cyclodextrin in male and female rats following a loading dose and constant rate infusion.

Treatment of acute pain in cats (2016)
Journal Article

The cat's popularity as a pet continues to grow, with the most recent surveys showing approximately 17% of the population live with cats. This increased popularity of cats invariably means that more cats are presented to veterinary surgeons for surge... Read More about Treatment of acute pain in cats.