All Outputs (7)

The association between benzodiazepines and influenza-like illness-related pneumonia and mortality: a survival analysis using UK Primary Care data (2016)
Journal Article
Nakafero, G., Sanders, R. D., Nguyen-Van-Tam, J. S., & Myles, P. R. (2016). The association between benzodiazepines and influenza-like illness-related pneumonia and mortality: a survival analysis using UK Primary Care data. Pharmacoepidemiology and Drug Safety, 25(11), 1263-1273. https://doi.org/10.1002/pds.4028

Purpose: Bacterial superinfections, including pneumonia, are frequent complications of influenza-like illness (ILI). Clinical and laboratory evidence suggests that benzodiazepines and Z-drugs may influence susceptibility to infections and mortality.... Read More about The association between benzodiazepines and influenza-like illness-related pneumonia and mortality: a survival analysis using UK Primary Care data.

Risk of nosocomial respiratory syncytial virus infection and effectiveness of control measures to prevent transmission events: a systematic review (2016)
Journal Article
French, C. E., McKenzie, B. C., Coope, C., Rajanaidu, S., Paranthaman, K., Pebody, R., …Beck, C. R. (2016). Risk of nosocomial respiratory syncytial virus infection and effectiveness of control measures to prevent transmission events: a systematic review. Influenza and Other Respiratory Viruses, 10(4), 268-290. https://doi.org/10.1111/irv.12379

Respiratory syncytial virus (RSV) causes a significant public health burden, and outbreaks among vulnerable patients in hospital settings are of particular concern. We reviewed published and unpublished literature from hospital settings to assess: (i... Read More about Risk of nosocomial respiratory syncytial virus infection and effectiveness of control measures to prevent transmission events: a systematic review.

Corticosteroids as adjunctive therapy in the treatment of influenza (2016)
Journal Article
Rodrigo, C., Leonardi-Bee, J., Nguyen-Van-Tam, J., & Lim, W. S. (2016). Corticosteroids as adjunctive therapy in the treatment of influenza. Cochrane Database of Systematic Reviews, Article CD010406. https://doi.org/10.1002/14651858.CD010406.pub2

Background: Specific treatments for influenza are limited to neuraminidase inhibitors and adamantanes. Corticosteroids show evidence of benefit in sepsis and related conditions, most likely due to their anti-inflammatory and immunomodulatory properti... Read More about Corticosteroids as adjunctive therapy in the treatment of influenza.

Cohort profile: the Flu Watch Study (2016)
Journal Article
Fragaszy, E. B., Warren-Gash, C., Wang, L., Copas, A., Dukes, O., Edmunds, W. J., …Hayward, A. C. (in press). Cohort profile: the Flu Watch Study. International Journal of Epidemiology, https://doi.org/10.1093/ije/dyv370

Influenza is a common, highly contagious respiratory virus which infects all age groups, causing a range of outcomes from asymptomatic infection and mild respiratory disease to severe respiratory disease and death.1 If infected, the adaptive immune s... Read More about Cohort profile: the Flu Watch Study.

Impact of neuraminidase inhibitors on influenza A(H1N1)pdm09-related pneumonia: an individual participant data meta-analysis (2016)
Journal Article
Muthuri, S. G., Venkatesan, S., Myles, P. R., Leonardi-Bee, J., Lim, W. S., Al Mamun, A., …Nguyen-Van-Tam, J. S. (2016). Impact of neuraminidase inhibitors on influenza A(H1N1)pdm09-related pneumonia: an individual participant data meta-analysis. Influenza and Other Respiratory Viruses, 10(3), 192-204. https://doi.org/10.1111/irv.12363

BACKGROUND: The impact of neuraminidase inhibitors (NAIs) on influenza‐related pneumonia (IRP) is not established. Our objective was to investigate the association between NAI treatment and IRP incidence and outcomes in patients hospitalised with A(H... Read More about Impact of neuraminidase inhibitors on influenza A(H1N1)pdm09-related pneumonia: an individual participant data meta-analysis.

Increased risk of A(H1N1)pdm09 influenza infection in UK pig industry workers compared to a general population cohort (2016)
Journal Article
the Combating Swine Influenza (COSI) Consortium, the Flu Watch Group, Fragaszy, E., Ishola, D. A., Brown, I. H., Enstone, J., …Wood, J. L. (2016). Increased risk of A(H1N1)pdm09 influenza infection in UK pig industry workers compared to a general population cohort. Influenza and Other Respiratory Viruses, 10(4), 291-300. https://doi.org/10.1111/irv.12364

Background: Pigs are mixing vessels for influenza viral reassortment but the extent of influenza transmission between swine and humans is not well understood. Objectives: To assess whether occupational exposure to pigs is a risk factor for human... Read More about Increased risk of A(H1N1)pdm09 influenza infection in UK pig industry workers compared to a general population cohort.

The roles of transportation and transportation hubs in the propagation of influenza and coronaviruses: a systematic review (2016)
Journal Article
Browne, A., Ahmad, S. S., Beck, C. R., & Nguyen-Van-Tam, J. (in press). The roles of transportation and transportation hubs in the propagation of influenza and coronaviruses: a systematic review. Journal of Travel Medicine, 23(1), https://doi.org/10.1093/jtm/tav002

BACKGROUND: Respiratory viruses spread in humans across wide geographical areas in short periods of time, resulting in high levels of morbidity and mortality. We undertook a systematic review to assess the evidence that air, ground and sea mass trans... Read More about The roles of transportation and transportation hubs in the propagation of influenza and coronaviruses: a systematic review.