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All Outputs (55)

Dopamine D1-like receptors modulate synchronized oscillations in the hippocampal–prefrontal–amygdala circuit in contextual fear (2023)
Journal Article

Contextual fear conditioning (CFC) is mediated by a neural circuit that includes the hippocampus, prefrontal cortex, and amygdala, but the neurophysiological mechanisms underlying the regulation of CFC by neuromodulators remain unclear. Dopamine D1-l... Read More about Dopamine D1-like receptors modulate synchronized oscillations in the hippocampal–prefrontal–amygdala circuit in contextual fear.

Attitudes to the use of animals in biomedical research: Effects of stigma and selected research project summaries (2023)
Journal Article

Three groups of participants (largely recruited from the UK) completed a survey to examine attitudes to the use of animals in biomedical research, after reading the lay (N = 182) or technical (N = 201) summary of a research project, or no summary (N... Read More about Attitudes to the use of animals in biomedical research: Effects of stigma and selected research project summaries.

From safety to frustration: The neural substrates of inhibitory learning in aversive and appetitive conditioning procedures (2023)
Journal Article

Inhibitory associative learning counters the effects of excitatory learning, whether appetitively or aversively motivated. Moreover, the affective responses accompanying the inhibitory associations are of opponent valence to the excitatory conditione... Read More about From safety to frustration: The neural substrates of inhibitory learning in aversive and appetitive conditioning procedures.

Endocannabinoid metabolism inhibition has no effect on spontaneous fear recovery or extinction resistance in Lister hooded rats (2022)
Journal Article

Endocannabinoid transmission is emerging as a target for treating anxiety-related disorders, given its regulation of fear extinction. Boosting anandamide levels via inhibition of its metabolism by fatty acid amide hydrolase (FAAH) can enhance extinct... Read More about Endocannabinoid metabolism inhibition has no effect on spontaneous fear recovery or extinction resistance in Lister hooded rats.

Cannabidiol Prevents Spontaneous Fear Recovery after Extinction and Ameliorates Stress-Induced Extinction Resistance (2022)
Journal Article

Cannabidiol, the main non-psychotropic constituent of cannabis, has potential as a treatment for anxiety-related disorders since it reduces learned fear expression and enhances fear extinction. The return of fear over time after successful extinction... Read More about Cannabidiol Prevents Spontaneous Fear Recovery after Extinction and Ameliorates Stress-Induced Extinction Resistance.

Attitudes to animal use of named species for different purposes: effects of speciesism, individualising morality, likeability and demographic factors (2022)
Journal Article

Attitudes to animals and their use are becoming increasingly important for the success of conservation and environmental initiatives. Beliefs about animals, their perceived emotional appeal, as well as individuals’ moral capacities are all likely dri... Read More about Attitudes to animal use of named species for different purposes: effects of speciesism, individualising morality, likeability and demographic factors.

Hippocampal Disinhibition Reduces Contextual and Elemental Fear Conditioning While Sparing the Acquisition of Latent Inhibition (2022)
Journal Article

Hippocampal neural disinhibition, i.e., reduced GABAergic inhibition, is a key feature of schizophrenia pathophysiology. The hippocampus is an important part of the neural circuitry that controls fear conditioning and can also modulate prefrontal and... Read More about Hippocampal Disinhibition Reduces Contextual and Elemental Fear Conditioning While Sparing the Acquisition of Latent Inhibition.

Muscimol-induced inactivation of the anterior cingulate cortex does not impair trace fear conditioning in the rat (2020)
Journal Article

Previous studies suggest that trace conditioning depends on the anterior cingulate cortex (ACC). To examine the role of ACC in trace fear conditioning further, 48 rats were surgically prepared for infusion with saline or 62.5 or 125 µg/side muscimol... Read More about Muscimol-induced inactivation of the anterior cingulate cortex does not impair trace fear conditioning in the rat.

Man's best friends: attitudes towards the use of different kinds of animal depend on belief in different species' mental capacities and purpose of use (2020)
Journal Article

The animal purpose questionnaire (APQ) is a new instrument to measure human attitudes to animal use systematically across both species and purpose of use. This offers a more fine-grained approach to our understanding of how the belief in a specific a... Read More about Man's best friends: attitudes towards the use of different kinds of animal depend on belief in different species' mental capacities and purpose of use.

Some animals are more equal than others: Validation of a new scale to measure how attitudes to animals depend on species and human purpose of use (2020)
Journal Article

© 2020 Bradley et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cr... Read More about Some animals are more equal than others: Validation of a new scale to measure how attitudes to animals depend on species and human purpose of use.

Infusions of scopolamine in dorsal hippocampus reduce anticipatory responding in an appetitive trace conditioning procedure (2018)
Journal Article

Trace conditioning is impaired by lesions to dorsal hippocampus, as well as by treatment with the muscarinic acetylcholine antagonist scopolamine. However, the role of muscarinic receptors within hippocampus has received little attention. The present... Read More about Infusions of scopolamine in dorsal hippocampus reduce anticipatory responding in an appetitive trace conditioning procedure.

Role of the anterior cingulate cortex in the retrieval of novel object recognition memory after a long delay (2017)
Journal Article

Previous in vivo electrophysiological studies suggest that the anterior cingulate cortex (ACgx) is an important substrate of novel object recognition (NOR) memory. However, intervention studies are needed to confirm this conclusion and permanent lesi... Read More about Role of the anterior cingulate cortex in the retrieval of novel object recognition memory after a long delay.