All Outputs (30)

Paediatric dermatology teleconsultations: a survey of healthcare professionals in the UK (2023)
Journal Article

The COVID-19 pandemic catapulted dermatology services into a digital era, with the rapid introduction of teleconsultations. The UK National Health Service operational planning guidance recommends ≥ 25% of consultations are delivered remotely. There i... Read More about Paediatric dermatology teleconsultations: a survey of healthcare professionals in the UK.

Risk of liver fibrosis associated with long-term methotrexate therapy may be overestimated (2023)
Journal Article

Background & Aims The risk of significant liver fibrosis from prolonged methotrexate (MTX) exposure has been estimated at around 5%, prompting intensive monitoring strategies. However, the evidence is derived from retrospective studies that under-re... Read More about Risk of liver fibrosis associated with long-term methotrexate therapy may be overestimated.

Risk of liver fibrosis associated with long-term methotrexate therapy may be overestimated (2023)
Journal Article

Background & Aims: The risk of significant liver fibrosis from prolonged methotrexate (MTX) exposure has been estimated at around 5%, prompting intensive monitoring strategies. However, the evidence is derived from retrospective studies that under-re... Read More about Risk of liver fibrosis associated with long-term methotrexate therapy may be overestimated.

How is oral isotretinoin prescribed for the treatment of acne vulgaris? Results from a UK Dermatology Clinical Trials Network (UKDCTN) and British Dermatological Nursing Group (BDNG) survey of health professionals (2022)
Journal Article

We undertook a survey of UK healthcare professionals through the UKDCTN and BDNG to understand clinicians’ routine practice prescribing oral isotretinoin for treatment of acne vulgaris (acne). We also wanted to understand clinicians’ experiences and... Read More about How is oral isotretinoin prescribed for the treatment of acne vulgaris? Results from a UK Dermatology Clinical Trials Network (UKDCTN) and British Dermatological Nursing Group (BDNG) survey of health professionals.

Where are we with developing diagnostic criteria for skin diseases? Mapping the evidence in 2021 (2022)
Journal Article

The breadth and scope of dermatological diagnostic criteria is currently unknown. We created a map of diagnostic criteria to provide a panoramic view of past and ongoing research to develop dermatological diagnostic criteria. We analysed studies for... Read More about Where are we with developing diagnostic criteria for skin diseases? Mapping the evidence in 2021.

Identifying the best predictive diagnostic criteria for psoriasis in children (< 18 years): a UK multicentre case–control diagnostic accuracy study (DIPSOC study) (2021)
Journal Article

Background In children, psoriasis can be challenging to diagnose. Difficulties arise from differences in the clinical presentation compared to adults. Objectives To test the diagnostic accuracy of previously agreed consensus criteria and develop... Read More about Identifying the best predictive diagnostic criteria for psoriasis in children (< 18 years): a UK multicentre case–control diagnostic accuracy study (DIPSOC study).

Can atopic eczema and psoriasis coexist? A systematic review and meta?analysis (2021)
Journal Article

Importance: Previous studies report both co-existence and mutual exclusivity of atopic eczema (AE) and psoriasis, but these have not been appraised systematically. Knowledge of such disease association throws light on disease mechanisms and may influ... Read More about Can atopic eczema and psoriasis coexist? A systematic review and meta?analysis.

Fragranced hand gels: beware the risk of contact allergy (2021)
Journal Article

Outcome assessment in dermatology clinical trials and cochrane reviews: call for a dermatology?specific outcome taxonomy (2020)
Journal Article

Background: Standardized outcome reporting is crucial for trial evidence synthesis and translation of findings into clinical decision making. The OMERACT 2.0 Filter and COMET outcome domain taxonomy propose frameworks for consistent reporting of outc... Read More about Outcome assessment in dermatology clinical trials and cochrane reviews: call for a dermatology?specific outcome taxonomy.

Protocol for a case-control diagnostic accuracy study to develop diagnostic criteria for psoriasis in children (DIPSOC study): a multicentre study recruiting in UK paediatric dermatology clinics (2019)
Journal Article

Introduction Diagnosing psoriasis in children can be challenging. Early and accurate diagnosis is important to ensure patients receive psoriasis specific treatment and monitoring. It is recognised that the physical, psychological, quality of life, fi... Read More about Protocol for a case-control diagnostic accuracy study to develop diagnostic criteria for psoriasis in children (DIPSOC study): a multicentre study recruiting in UK paediatric dermatology clinics.

Developing diagnostic criteria for psoriasis in children (2019)
Dataset

Development of clinical diagnostic criteria for plaque psoriasis in children: an eDelphi consensus study with the International Psoriasis Council (2019)
Journal Article

Psoriasis in children can be a challenging diagnosis: the clinical presentation is often more subtle, may occur in covered sites and can be an unexpected diagnosis as psoriasis if often thought to occur at older ages. Poor recognition and delayed dia... Read More about Development of clinical diagnostic criteria for plaque psoriasis in children: an eDelphi consensus study with the International Psoriasis Council.

Cochrane reviews and dermatological trials outcome concordance: why Core Outcome Sets could make trial results more usable (2018)
Journal Article

Evidence-based healthcare requires that relevant outcomes for patients are included in clinical trials which investigating treatment effects allowing subsequent systematic reviews to summarize all relevant evidence to guide clinical practice. Current... Read More about Cochrane reviews and dermatological trials outcome concordance: why Core Outcome Sets could make trial results more usable.

Identifying key components for a psychological intervention for people with vitiligo: a quantitative and qualitative study in the United Kingdom using web-based questionnaires of people with vitiligo and healthcare professionals (2018)
Journal Article

Background: Psychological interventions are recommended as part of routine management of vitiligo. However, the development and effectiveness of such interventions have been rarely addressed. This study aimed to identify key components for a psycholo... Read More about Identifying key components for a psychological intervention for people with vitiligo: a quantitative and qualitative study in the United Kingdom using web-based questionnaires of people with vitiligo and healthcare professionals.

Long-term topical corticosteroid use and risk of skin cancer: a systematic review (2018)
Journal Article

Objective: The objective of this systematic review was to synthesize available research evidence to determine the risk of skin cancer in patients with long-term use of topical corticosteroids (TCS). Introduction: Topical corticosteroids are one of... Read More about Long-term topical corticosteroid use and risk of skin cancer: a systematic review.

Quality of life in people with vitiligo: a systematic review and meta-analysis (2017)
Journal Article

Vitiligo is cosmetically disfiguring and has profound psychosocial effects due to stigmatization, problems in sexual function, anxiety, self-esteem and difficulty finding employment. Previous studies suggest a reduction in quality of life (QoL) due t... Read More about Quality of life in people with vitiligo: a systematic review and meta-analysis.

A systematic review of diagnostic criteria for psoriasis in adults and children: evidence from studies with a primary aim to develop or validate diagnostic criteria (2017)
Journal Article

Background: The diagnosis of psoriasis in adults and children is made clinically, for both patient management and the selection of participants in research. Diagnostic criteria provide a structure for clinical assessment, which in turn helps standard... Read More about A systematic review of diagnostic criteria for psoriasis in adults and children: evidence from studies with a primary aim to develop or validate diagnostic criteria.

Putting UK DCTN studies into practice: a nurse and patient perspective of the investigator day for the BLISTER and STOP GAP trials (2017)
Journal Article

The BLISTER and STOP GAP studies are two important trials in the field of dermatology and also for the UK Dermatology Clinical Trials Network (UK DCTN) as a collaborative network. They make a significant contribution to our limited evidence base for... Read More about Putting UK DCTN studies into practice: a nurse and patient perspective of the investigator day for the BLISTER and STOP GAP trials.

Early recognition and detection of juvenile psoriatic arthritis: a call for a standardized approach to screening (2017)
Journal Article

Background: National Institute for Health and Care Excellence (NICE) guidelines recommend annual screening for psoriatic arthritis (PsA) in all patients with psoriasis. Currently, no validated assessment tools have been recommended for screening for... Read More about Early recognition and detection of juvenile psoriatic arthritis: a call for a standardized approach to screening.

Long-term topical corticosteroid use and risk of skin cancer: a systematic review protocol (2016)
Journal Article

Review question/objective: The objective of this systematic review is to synthesize the best available research evidence to determine the risk of skin cancer in patients on long-term use of topical corticosteroids. Specifically the review question is... Read More about Long-term topical corticosteroid use and risk of skin cancer: a systematic review protocol.