All Outputs (155)
Hyperosmolar dehydration: a predictor of kidney injury and outcome in hospitalised older adults (2019)
Journal Article
© 2019 The Author(s) Background & aims: Hospitalised older adults are vulnerable to dehydration. However, the prevalence of hyperosmolar dehydration (HD) and its impact on outcome is unknown. Serum osmolality is not measured routinely but osmolarity,... Read More about Hyperosmolar dehydration: a predictor of kidney injury and outcome in hospitalised older adults.
Publication governance in Clinical Nutrition (2019)
Journal Article
A randomized, controlled, double-blind crossover study on the effects of isoeffective and isovolumetric intravenous crystalloid and gelatin on blood volume, and renal and cardiac hemodynamics (2019)
Journal Article
Background & aims Blood volume expanding properties of colloids are superior to crystalloids. In addition to oncotic/osmotic properties, the electrolyte composition of infusions may have important effects on visceral perfusion, with infusions contai... Read More about A randomized, controlled, double-blind crossover study on the effects of isoeffective and isovolumetric intravenous crystalloid and gelatin on blood volume, and renal and cardiac hemodynamics.
Modulation of T regulatory and dendritic cell phenotypes following ingestion of Bifidobacterium longum, active hexose correlated compound (AHCC®) and azithromycin in healthy individuals (2019)
Journal Article
The probiotic Bifidus BB536 (BB536), which contains Bifidobacterium longum, has been shown to have enhanced probiotic effects when given together with a standardized extract of cultured Lentinula edodes mycelia (AHCC®, Amino Up Co. Ltd., Sapporo, Jap... Read More about Modulation of T regulatory and dendritic cell phenotypes following ingestion of Bifidobacterium longum, active hexose correlated compound (AHCC®) and azithromycin in healthy individuals.
Computer Tomography-Based Psoas Skeletal Muscle Area and Radiodensity are Poor Sentinels for Whole L3 Skeletal Muscle Values (2019)
Journal Article
Background and aims Computed tomography (CT)-based measurement of skeletal muscle cross-sectional area (CSA) and Hounsfield unit (HU) radiodensity are used to assess the presence of sarcopenia and myosteatosis, respectively. The validated CT-based t... Read More about Computer Tomography-Based Psoas Skeletal Muscle Area and Radiodensity are Poor Sentinels for Whole L3 Skeletal Muscle Values.
Outcomes Following an Index Emergency Admission With Cholecystitis: A National Cohort Study (2019)
Journal Article
Objective: The objective of this study was to evaluate the differences between patients who undergo cholecystectomy following index admission for cholecystitis, and those who are managed nonoperatively. Summary Background Data: Index emergency... Read More about Outcomes Following an Index Emergency Admission With Cholecystitis: A National Cohort Study.
IgG4 Expression Correlates with Poor Prognosis in Pancreatic Adenocarcinoma (2019)
Conference Proceeding
Purpose of the study: IgG4, a member of the immunoglobulin family, has been implicated in the pathobiology of inflammatory disease (including autoimmune pancreatitis) and cancers. Its role in pancreatic cancers however remains to be elucidated. This... Read More about IgG4 Expression Correlates with Poor Prognosis in Pancreatic Adenocarcinoma.
Winter cancellations of elective surgical procedures in the United Kingdom: A questionnaire survey of patients on the economic and psychological impact (2019)
Journal Article
Objectives: To quantify the economic and psychological impact of the cancellation of operations due to winter pressures on patients, their families and the economy. Design: This questionnaire study was designed with the help of patient groups. Dat... Read More about Winter cancellations of elective surgical procedures in the United Kingdom: A questionnaire survey of patients on the economic and psychological impact.
Winter cancellations of elective surgical procedures in the UK: a questionnaire survey of patients on the economic and psychological impact (2019)
Journal Article
Objectives To quantify the economic and psychological impact of the cancellation of operations due to winter pressures on patients, their families and the economy. Design This questionnaire study was designed with the help of patient groups. Data... Read More about Winter cancellations of elective surgical procedures in the UK: a questionnaire survey of patients on the economic and psychological impact.
Perioperative Probiotics or Synbiotics in Adults Undergoing Elective Abdominal Surgery: A Systematic Review and Meta-analysis of Randomized Controlled Trials (2019)
Journal Article
This meta-analysis of 34 randomized controlled trials reporting on 2723 participants has shown that perioperative administration of either probiotics or synbiotics was well tolerated and significantly reduced the risk of infectious complications foll... Read More about Perioperative Probiotics or Synbiotics in Adults Undergoing Elective Abdominal Surgery: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
Thioredoxin system protein expression in carcinomas of the pancreas, bile duct and ampulla (2019)
Working Paper
Background: Pancreatic cancer (PC), including the ampulla and bile duct, is very aggressive, and thus difficult to treat with effective therapies. The current treatment options have failed to improve PC five-year survival rates over the last 30 to 40... Read More about Thioredoxin system protein expression in carcinomas of the pancreas, bile duct and ampulla.
Meta-analysis of goal directed fluid therapy using transoesophageal doppler in patients undergoing elective colorectal surgery (2019)
Journal Article
Background: Intraoperative goal-directed fluid therapy (GDFT) is recommended for intraoperative fluid management for elective colorectal surgery in most perioperative guidelines. However, the evidence in elective colorectal surgery alone is not welle... Read More about Meta-analysis of goal directed fluid therapy using transoesophageal doppler in patients undergoing elective colorectal surgery.
A systematic review of patient reported outcome measures (PROMs) and quality of life reporting in patients undergoing laparoscopic cholecystectomy (2019)
Journal Article
Background Patient Reported Outcome Measures (PROMs) provide a valuable means of measuring outcomes subjectively from a patient's perspective, facilitating the assessment of service quality across healthcare providers, and assisting patients and clin... Read More about A systematic review of patient reported outcome measures (PROMs) and quality of life reporting in patients undergoing laparoscopic cholecystectomy.
Improving outcomes with a little EFFORT (2019)
Journal Article
Oral antibiotic preparation in colorectal surgery: is there more to debate? (2019)
Journal Article
Opioid stewardship: a need for opioid discharge guidance: comment on Br J Anaesth 2018 Dec 28 (2019)
Journal Article
We read with interest the special and insightful article by Soffin and colleagues1 on the prescription opioid crisis. They carefully examine many of the drivers for subsequent opioid dependence after surgery and provide suggestions on how practice ca... Read More about Opioid stewardship: a need for opioid discharge guidance: comment on Br J Anaesth 2018 Dec 28.
The Impact of Preoperative Immune Modulating Nutrition on Outcomes in Patients Undergoing Surgery for Gastrointestinal Cancer: A Systematic Review and Meta-analysis (2019)
Journal Article
Objective: To define the influence of preoperative immune modulating nutrition (IMN) on postoperative outcomes in patients undergoing surgery for gastrointestinal cancer. Summary background data: Although studies have shown that perioperative IMN... Read More about The Impact of Preoperative Immune Modulating Nutrition on Outcomes in Patients Undergoing Surgery for Gastrointestinal Cancer: A Systematic Review and Meta-analysis.
The death of Charlotte Brontë from hyperemesis gravidarum and refeeding syndrome: A new perspective (2019)
Journal Article
Many theories have been advanced concerning the cause of Charlotte Bronte’s death, none of which fully explain all the symptoms she experienced in the course of her final illness. Her death certificate records the cause of death as phthisis (tubercul... Read More about The death of Charlotte Brontë from hyperemesis gravidarum and refeeding syndrome: A new perspective.
The effects of terlipressin and direct portacaval shunting on liver hemodynamics following 80% hepatectomy in the pig (2019)
Journal Article
Liver failure is the major cause of death following liver resection. Post-resection portal venous pressure (PVP) predicts liver failure, is implicated in its pathogenesis and when PVP is reduced, rates of liver dysfunction decrease. The aim of this s... Read More about The effects of terlipressin and direct portacaval shunting on liver hemodynamics following 80% hepatectomy in the pig.