All Outputs (43)

Mutation in OsCADT1 enhances cadmium tolerance and enriches selenium in rice grain (2019)
Journal Article
Chen, J., Huang, X., Salt, D. E., & Zhao, F. (2020). Mutation in OsCADT1 enhances cadmium tolerance and enriches selenium in rice grain. New Phytologist, 226(3), 838-850. https://doi.org/10.1111/nph.16404

•How cadmium (Cd) tolerance in rice is regulated remains poorly understood. We used a forward genetic approach to investigate Cd tolerance in rice. •Using root elongation assay, we isolated a rice mutant with enhanced Cd tolerance, cadt1, from an EMS... Read More about Mutation in OsCADT1 enhances cadmium tolerance and enriches selenium in rice grain.

Transcriptional plasticity buffers genetic variation in zinc homeostasis (2019)
Journal Article
Pita-Barbosa, A., Ricachenevsky, F. K., Wilson, M., Dottorini, T., & Salt, D. E. (2019). Transcriptional plasticity buffers genetic variation in zinc homeostasis. Scientific Reports, 9, Article 19482. https://doi.org/10.1038/s41598-019-55736-0

In roots of Arabidopsis thaliana, Zn can be either loaded into the xylem for translocation to the shoot or stored in vacuoles. Vacuolar storage is achieved through the action of the Zn/Cd transporter HMA3 (Heavy Metal Atpase 3). The Col-0 accession h... Read More about Transcriptional plasticity buffers genetic variation in zinc homeostasis.

The Intensity of Manganese Deficiency Strongly Affects Root Endodermal Suberization and Ion Homeostasis (2019)
Journal Article
Chen, A., Husted, S., Salt, D. E., Schjoerring, J. K., & Persson, D. P. (2019). The Intensity of Manganese Deficiency Strongly Affects Root Endodermal Suberization and Ion Homeostasis. Plant Physiology, 181(2), 729-742. https://doi.org/10.1104/pp.19.00507

Manganese (Mn) deficiency affects various processes in plant shoots. However, the functions of Mn in roots and the processesinvolved in root adaptation to Mn deficiency are largely unresolved. Here, we show that the suberization of endodermal cells i... Read More about The Intensity of Manganese Deficiency Strongly Affects Root Endodermal Suberization and Ion Homeostasis.

Variation in the BrHMA3 coding region controls natural variation in cadmium accumulation in Brassica rapa vegetables (2019)
Journal Article
Zhang, L., Wu, J., Tang, Z., Huang, X., Wang, X., Salt, D. E., & Zhao, F. (2019). Variation in the BrHMA3 coding region controls natural variation in cadmium accumulation in Brassica rapa vegetables. Journal of Experimental Botany, 70(20), 5865-5878. https://doi.org/10.1093/jxb/erz310

Brassica rapa includes several important leafy vegetable crops with the potential for high cadmium (Cd) accumulation, posing a risk to human health. This study aims to understand the genetic basis underlying the variation in Cd accumulation among B.... Read More about Variation in the BrHMA3 coding region controls natural variation in cadmium accumulation in Brassica rapa vegetables.

Epigenetic regulation of sulfur homeostasis in plants (2019)
Journal Article
Huang, X. Y., Li, M., Luo, R., Zhao, F. J., & Salt, D. E. (2019). Epigenetic regulation of sulfur homeostasis in plants. Journal of Experimental Botany, 70(16), 4171-4182. https://doi.org/10.1093/jxb/erz218

Plants have evolved sophisticated mechanisms for adaptation to fluctuating availability of nutrients in soil. Such mechanisms are of importance for plants to maintain homeostasis of nutrient elements for their development and growth. The molecular me... Read More about Epigenetic regulation of sulfur homeostasis in plants.

Soil carbonate drives local adaptation in Arabidopsis thaliana (2019)
Journal Article
Terés, J., Busoms, S., Perez Martín, L., Luís‐Villarroya, A., Flis, P., Álvarez‐Fernández, A., …Poschenrieder, C. (2019). Soil carbonate drives local adaptation in Arabidopsis thaliana. Plant, Cell and Environment, 42(8), 2384-2398. https://doi.org/10.1111/pce.13567

High soil carbonate limits crop performance especially in semiarid or arid climates. To understand how plants adapt to such soils, we explored natural variation in tolerance to soil carbonate in small local populations (demes) of Arabidopsis thaliana... Read More about Soil carbonate drives local adaptation in Arabidopsis thaliana.

Natural variation in a molybdate transporter controls grain molybdenum concentration in rice (2018)
Journal Article
Huang, X., Liu, H., Zhu, Y., Pinson, S. R. M., Lin, H., Guerinot, M. L., …Salt, D. E. (2019). Natural variation in a molybdate transporter controls grain molybdenum concentration in rice. New Phytologist, 221(4), 1983-1997. https://doi.org/10.1111/nph.15546

© 2018 The Authors. New Phytologist © 2018 New Phytologist Trust Molybdenum (Mo) is an essential micronutrient for most living organisms, including humans. Cereals such as rice (Oryza sativa) are the major dietary source of Mo. However, little is kno... Read More about Natural variation in a molybdate transporter controls grain molybdenum concentration in rice.

Genome-Wide Association Studies Reveal the Genetic Basis of Ionomic Variation in Rice (2018)
Journal Article
Yang, M., Lu, K., Zhao, F., Xie, W. X., Ramakrishna, P., Wang, G., …Lian, X. (2018). Genome-Wide Association Studies Reveal the Genetic Basis of Ionomic Variation in Rice. Plant Cell, 30(11), 2720–2740. https://doi.org/10.1105/tpc.18.00375

Rice (Oryza sativa) is an important dietary source of both essential micronutrients and toxic trace elements for humans. The genetic basis underlying the variations in the mineral composition, the ionome, in rice remains largely unknown. Here, we des... Read More about Genome-Wide Association Studies Reveal the Genetic Basis of Ionomic Variation in Rice.

Hidden variation in polyploid wheat drives local adaptation (2018)
Journal Article
Gardiner, L., Joynson, R., Omony, J., Rusholme-Pilcher, R., Olohan, L., Lang, D., …Hall, A. (2018). Hidden variation in polyploid wheat drives local adaptation. Genome Research, 28(9), 1319-1332. https://doi.org/10.1101/gr.233551.117

Wheat has been domesticated into a large number of agricultural environments and has the ability to adapt to diverse environments. To understand this process, we survey genotype, repeat content, and DNA methylation across a bread wheat landrace colle... Read More about Hidden variation in polyploid wheat drives local adaptation.

Elemental profiling of rice FOX lines leads to characterization of a new Zn plasma membrane transporter, OsZIP7 (2018)
Journal Article
Ricachenevsky, F. K., Punshon, T., Lee, S., Oliveira, B. H. N., Trenz, T. S., Maraschin, F. D. S., …Guerinot, M. L. (in press). Elemental profiling of rice FOX lines leads to characterization of a new Zn plasma membrane transporter, OsZIP7. Frontiers in Plant Science, 9, https://doi.org/10.3389/fpls.2018.00865

Iron (Fe) and zinc (Zn) are essential micronutrients required for proper development in both humans and plants. Rice (Oryza sativa L.) grains are the staple food for nearly half of the world’s population, but a poor source of metals such as Fe and Zn... Read More about Elemental profiling of rice FOX lines leads to characterization of a new Zn plasma membrane transporter, OsZIP7.

A new vesicle trafficking regulator CTL1 plays a crucial role in ion homeostasis (2017)
Journal Article
Gao, Y., Chen, J., Chen, Z., An, D., Lv, Q., Han, M., …Chao, D. (2017). A new vesicle trafficking regulator CTL1 plays a crucial role in ion homeostasis. PLoS Biology, 15(12), Article e2002978. https://doi.org/10.1371/journal.pbio.2002978

Ion homeostasis is essential for plant growth and environmental adaptation, and maintaining ion homeostasis requires the precise regulation of various ion transporters, as well as correct root patterning. However, the mechanisms underlying these proc... Read More about A new vesicle trafficking regulator CTL1 plays a crucial role in ion homeostasis.

Dissecting the components controlling root-to-shoot arsenic translocation in Arabidopsis thaliana (2017)
Journal Article
Wang, C., Na, G., Bermejo, E. S., Chen, Y., Banks, J. A., Salt, D. E., & Zhao, F. (2018). Dissecting the components controlling root-to-shoot arsenic translocation in Arabidopsis thaliana. New Phytologist, 217(1), 206-218. https://doi.org/10.1111/nph.14761

Arsenic (As) is an important environmental and food-chain toxin. We investigated the key components controlling As accumulation and tolerance in Arabidopsis thaliana. We tested the effects of different combinations of gene knockout, including ar... Read More about Dissecting the components controlling root-to-shoot arsenic translocation in Arabidopsis thaliana.

Natural variation in Arabidopsis thaliana reveals shoot ionome, biomass, and gene expression changes as biomarkers for zinc deficiency tolerance (2017)
Journal Article
Campos, A. C. A., Kruijer, W., Alexander, R., Akkers, R. C., Danku, J., Salt, D. E., & Aarts, M. G. (2017). Natural variation in Arabidopsis thaliana reveals shoot ionome, biomass, and gene expression changes as biomarkers for zinc deficiency tolerance. Journal of Experimental Botany, 68(13), 3643-3656. https://doi.org/10.1093/jxb/erx191

Zinc (Zn) is an essential nutrient for plants, with a crucial role as a cofactor for many enzymes. Approximately one-third of the global arable land area is Zn deficient, leading to reduced crop yield and quality. To improve crop tolerance to Zn defi... Read More about Natural variation in Arabidopsis thaliana reveals shoot ionome, biomass, and gene expression changes as biomarkers for zinc deficiency tolerance.

BRUTUS and its paralogs, BTS LIKE1 and BTS LIKE2, encode important negative regulators of the iron deficiency response in Arabidopsis thaliana (2017)
Journal Article
Hindt, M. N., Akmakjian, G. Z., Pivarski, K. L., Punshon, T., Baxter, I., Salt, D. E., & Guerinot, M. L. (2017). BRUTUS and its paralogs, BTS LIKE1 and BTS LIKE2, encode important negative regulators of the iron deficiency response in Arabidopsis thaliana. Metallomics, 9(7), https://doi.org/10.1039/c7mt00152e

Iron (Fe) is required for plant health, but it can also be toxic when present in excess. Therefore, Fe levels must be tightly controlled. The Arabidopsis thaliana E3 ligase BRUTUS (BTS) is involved in the negative regulation of the Fe deficiency resp... Read More about BRUTUS and its paralogs, BTS LIKE1 and BTS LIKE2, encode important negative regulators of the iron deficiency response in Arabidopsis thaliana.

OsHAC1;1 and OsHAC1;2 function as arsenate reductases and regulate arsenic accumulation (2016)
Journal Article
Shi, S., Wang, T., Chen, Z., Tang, Z., Wu, Z., Salt, D. E., …Zhao, F. (in press). OsHAC1;1 and OsHAC1;2 function as arsenate reductases and regulate arsenic accumulation. Plant Physiology, 172(3), https://doi.org/10.1104/pp.16.01332

Rice is a major dietary source of the toxic metalloid arsenic (As). Reducing its accumulation in rice (Oryza sativa) grain is of critical importance to food safety. Rice roots take up arsenate and arsenite depending on the prevailing soil conditions.... Read More about OsHAC1;1 and OsHAC1;2 function as arsenate reductases and regulate arsenic accumulation.

Nuclear localised more sulphur accumulation1 epigenetically regulates sulphur homeostasis in Arabidopsis thaliana (2016)
Journal Article
Huang, X., Chao, D., Koprivova, A., Danku, J., Wirtz, M., Müller, S., …Salt, D. E. (2016). Nuclear localised more sulphur accumulation1 epigenetically regulates sulphur homeostasis in Arabidopsis thaliana. PLoS Genetics, 12(9), 1-29. https://doi.org/10.1371/journal.pgen.1006298

Sulphur (S) is an essential element for all living organisms. The uptake, assimilation and metabolism of S in plants are well studied. However, the regulation of S homeostasis remains largely unknown. Here, we report on the identification and charact... Read More about Nuclear localised more sulphur accumulation1 epigenetically regulates sulphur homeostasis in Arabidopsis thaliana.

Multi-element bioimaging of Arabidopsis thaliana roots (2016)
Journal Article
Persson, D. P., Chen, A., Aarts, M. G., Salt, D. E., Schjoerring, J. K., & Husted, S. (2016). Multi-element bioimaging of Arabidopsis thaliana roots. Plant Physiology, 172(2), https://doi.org/10.1104/pp.16.00770

Better understanding of root function is central for development of plants with more efficient nutrient uptake and translocation. We here present a method for multi-element bioimaging at the cellular level in roots of the genetic model system Arabido... Read More about Multi-element bioimaging of Arabidopsis thaliana roots.

Plant ionomics: from elemental profiling to environmental adaptation (2016)
Journal Article
Huang, X., & Salt, D. E. (in press). Plant ionomics: from elemental profiling to environmental adaptation. Molecular Plant, 9(6), https://doi.org/10.1016/j.molp.2016.05.003

Ionomics is a high-throughput elemental profiling approach to study the molecular mechanistic basis underlying mineral nutrient and trace element composition (also known as the ionome) of living organisms. Since the concept of ionomics was first intr... Read More about Plant ionomics: from elemental profiling to environmental adaptation.

The MYB36 transcription factor orchestrates Casparian strip formation (2015)
Journal Article
Kamiya, T., Borghi, M., Wang, P., Danku, J., Kalmbach, L., Hosmani, P. S., …Salt, D. E. (2015). The MYB36 transcription factor orchestrates Casparian strip formation. Proceedings of the National Academy of Sciences, 112(33), https://doi.org/10.1073/pnas.1507691112

The endodermis in roots acts as a selectivity filter for nutrient and water transport essential for growth and development. This selectivity is enabled by the formation of lignin-based Casparian strips. Casparian strip formation is initiated by the l... Read More about The MYB36 transcription factor orchestrates Casparian strip formation.

Genome-wide association mapping identifies a new arsenate reductase enzyme critical for limiting arsenic accumulation in plants (2014)
Journal Article
Chao, D., Chen, Y., Chen, J., Shi, S., Chen, Z., Wang, C., …Salt, D. E. (in press). Genome-wide association mapping identifies a new arsenate reductase enzyme critical for limiting arsenic accumulation in plants. PLoS Biology, 12(12), Article e1002009. https://doi.org/10.1371/journal.pbio.1002009

Inorganic arsenic is a carcinogen, and its ingestion through foods such as rice presents a significant risk to human health. Plants chemically reduce arsenate to arsenite. Using genome-wide association (GWA) mapping of loci controlling natural variat... Read More about Genome-wide association mapping identifies a new arsenate reductase enzyme critical for limiting arsenic accumulation in plants.