All Outputs (6)

Correlating gastric emptying of amphotericin B and paracetamol solid lipid nanoparticles with changes in particle surface chemistry (2016)
Journal Article

Oral delivery of pharmaceuticals requires that they retain their physical and chemical attributes during transit within the gastrointestinal (GI) tract, for the manifestation of desired therapeutic profiles. Solid lipid nanoparticles (SLNs) are used... Read More about Correlating gastric emptying of amphotericin B and paracetamol solid lipid nanoparticles with changes in particle surface chemistry.

Disruption of diphenylalanine assembly by a Boc-modified variant (2016)
Journal Article

Peptide-based biomaterials are key to the future of diagnostics and therapy, promoting applications such as tissue scaffolds and drug delivery vehicles. To realise the full potential of the peptide systems, control and optimisation of material proper... Read More about Disruption of diphenylalanine assembly by a Boc-modified variant.

Mucoadhesive chitosan-pectinate nanoparticles for the delivery of curcumin to the colon (2016)
Journal Article

In the present study, we report the properties of a mucoadhesive chitosan-pectinate nanoparticulate formulation able to retain its integrity in the milieu of the upper gastrointestinal tract and subsequently, mucoadhere and release curcumin in colon... Read More about Mucoadhesive chitosan-pectinate nanoparticles for the delivery of curcumin to the colon.

Controlling the physical dimensions of peptide nanotubes by supramolecular polymer coassembly (2016)
Journal Article

Molecular self-assembly of peptides into ordered nanotubes is highly important for various technological applications. Very short peptide building blocks, as short as dipeptides, can form assemblies with unique mechanical, optical, piezoelectric, and... Read More about Controlling the physical dimensions of peptide nanotubes by supramolecular polymer coassembly.

Imaging of Crystalline and Amorphous Surface Regions Using Time-of-Flight Secondary-Ion Mass Spectrometry (ToF-SIMS): Application to Pharmaceutical Materials (2016)
Journal Article

The structure of a material, in particular the extremes of crystalline and amorphous forms, significantly impacts material performance in numerous sectors such as semiconductors, energy storage, and pharmaceutical products, which are investigated in... Read More about Imaging of Crystalline and Amorphous Surface Regions Using Time-of-Flight Secondary-Ion Mass Spectrometry (ToF-SIMS): Application to Pharmaceutical Materials.

The effect of protein concentration on the viscosity of a recombinant albumin solution formulation (2016)
Journal Article

The effect of protein concentration on solution viscosity in a commercially available biopharmaceutical formulation of recombinant albumin (rAlbumin) was studied. The level of protein aggregation with concentration and its impact on solution viscosit... Read More about The effect of protein concentration on the viscosity of a recombinant albumin solution formulation.