All Outputs (8)

Immune-instructive materials as new tools for immunotherapy (2021)
Journal Article
Fisher, L. E., Kämmerling, L., Alexander, M. R., & Ghaemmaghami, A. M. (2022). Immune-instructive materials as new tools for immunotherapy. Current Opinion in Biotechnology, 74, 194-203. https://doi.org/10.1016/j.copbio.2021.11.005

Immune instructive materials, are materials with the ability to modulate or mimic the function of immune cells, provide exciting opportunities for developing new therapies in many areas including medical devices, chronic inflammation, cancer, and aut... Read More about Immune-instructive materials as new tools for immunotherapy.

Erratum: “Human lung-on-chips: Advanced systems for respiratory virus models and assessment of immune response” [Biomicrofluidics 15, 021501 (2021)] (2021)
Journal Article
Saygili, E., Yildiz-Ozturk, E., Green, M. J., Ghaemmaghami, A. M., & Yesil-Celiktas, O. (2021). Erratum: “Human lung-on-chips: Advanced systems for respiratory virus models and assessment of immune response” [Biomicrofluidics 15, 021501 (2021)]. Biomicrofluidics, 15(3), Article 039901. https://doi.org/10.1063/5.0056623

It has been drawn to the authors’ attention that our original article1 did not appropriately attribute portions of a figure that we had reused from Ref. 2. The figure caption as it should have appeared follows. FIG. 2. (a) Schematic depicting human l... Read More about Erratum: “Human lung-on-chips: Advanced systems for respiratory virus models and assessment of immune response” [Biomicrofluidics 15, 021501 (2021)].

Reversed-engineered human alveolar lung-on-a-chip model (2021)
Journal Article
Huang, D., Liu, T., Liao, J., Maharjan, S., Xie, X., Pérez, M., …Zhang, Y. S. (2021). Reversed-engineered human alveolar lung-on-a-chip model. Proceedings of the National Academy of Sciences, 118(19), Article e2016146118. https://doi.org/10.1073/pnas.2016146118

Here, we present a physiologically relevant model of the human pulmonary alveoli. This alveolar lung-on-a-chip platform is composed of a three-dimensional porous hydrogel made of gelatin methacryloyl with an inverse opal structure, bonded to a compar... Read More about Reversed-engineered human alveolar lung-on-a-chip model.

Mitigating the foreign body response through ‘immune-instructive’ biomaterials (2021)
Journal Article
Kämmerling, L., Fisher, L. E., Antmen, E., Simsek, G. M., Rostam, H. M., Vrana, N. E., & Ghaemmaghami, A. M. (2021). Mitigating the foreign body response through ‘immune-instructive’ biomaterials. Journal of Immunology and Regenerative Medicine, 12, Article 100040. https://doi.org/10.1016/j.regen.2021.100040

Objectives Biomaterials are routinely used in clinical applications. A key to the clinical success of implanted biomaterials is not eliciting detrimental immune responses. In this article, we provide an overview of immune responses to biomaterials,... Read More about Mitigating the foreign body response through ‘immune-instructive’ biomaterials.

Human lung-on-chips: Advanced systems for respiratory virus models and assessment of immune response (2021)
Journal Article
Saygili, E., Yildiz-Ozturk, E., Green, M. J., Ghaemmaghami, A. M., & Yesil-Celiktas, O. (2021). Human lung-on-chips: Advanced systems for respiratory virus models and assessment of immune response. Biomicrofluidics, 15(2), Article 021501. https://doi.org/10.1063/5.0038924

Respiratory viral infections are leading causes of death worldwide. A number of human respiratory viruses circulate in all age groups and adapt to person-to-person transmission. It is vital to understand how these viruses infect the host and how the... Read More about Human lung-on-chips: Advanced systems for respiratory virus models and assessment of immune response.

Development of a multiparametric (bio)sensing platform for continuous monitoring of stress metabolites (2021)
Journal Article
Chmayssem, A., Verplanck, N., Tanase, C. E., Costa, G., Monsalve-Grijalba, K., Amigues, S., …Mailley, P. (2021). Development of a multiparametric (bio)sensing platform for continuous monitoring of stress metabolites. Talanta, 229, Article 122275. https://doi.org/10.1016/j.talanta.2021.122275

There is a growing need for real-time monitoring of metabolic products that could reflect cell damages over extended periods. In this paper, we report the design and development of an original multiparametric (bio)sensing platform that is tailored fo... Read More about Development of a multiparametric (bio)sensing platform for continuous monitoring of stress metabolites.

Discovery of synergistic material-topography combinations to achieve immunomodulatory osteoinductive biomaterials using a novel in vitro screening method: The ChemoTopoChip (2021)
Journal Article
Burroughs, L., Amer, M., Vassey, M., Koch, B., Figueredo, G., Mukonoweshuro, B., …Alexander, M. R. (2021). Discovery of synergistic material-topography combinations to achieve immunomodulatory osteoinductive biomaterials using a novel in vitro screening method: The ChemoTopoChip. Biomaterials, 271, Article 120740. https://doi.org/10.1016/j.biomaterials.2021.120740

© 2021 The Authors Human mesenchymal stem cells (hMSCs) are widely represented in regenerative medicine clinical strategies due to their compatibility with autologous implantation. Effective bone regeneration involves crosstalk between macrophages an... Read More about Discovery of synergistic material-topography combinations to achieve immunomodulatory osteoinductive biomaterials using a novel in vitro screening method: The ChemoTopoChip.

Immunity in space: prokaryote adaptations and immune response in microgravity (2021)
Journal Article
Green, M. J., Aylott, J. W., Williams, P., Ghaemmaghami, A. M., & Williams, P. M. (2021). Immunity in space: prokaryote adaptations and immune response in microgravity. Life, 11(2), Article 112. https://doi.org/10.3390/life11020112

Immune dysfunction has long been reported by medical professionals regarding astronauts suffering from opportunistic infections both during their time in space and a short period afterwards once back on Earth. Various species of prokaryotes onboard t... Read More about Immunity in space: prokaryote adaptations and immune response in microgravity.