Psychological morbidity of celiac disease: a review of the literature

Zingone, Fabiana; Swift, Gillian L; Card, Timothy R.; Sanders, David S; Ludvigsson, Jonas F.; Bai, Julio C.

Abstract

BACKGROUND: Celiac disease has been linked to decreased quality of life and certain mood disorders. The effect of the gluten free diet on these psychological aspects of the disease is still unclear.

OBJECTIVES: The objective of this article is to review the literature on psychological morbidity of celiac disease.

METHODS: We performed a PubMed search for the time period from 1900 until June 1, 2014, to identify papers on psychological aspects of celiac disease looking specifically at quality of life, anxiety, depression and fatigue.

RESULTS: Anxiety, depression and fatigue are common complaints in patients with untreated celiac disease and contribute to lower quality of life. While aspects of these conditions may improve within a few months after starting a gluten-free diet, some patients continue to suffer from significant psychological morbidity. Psychological symptoms may affect the quality of life and the dietary adherence.

CONCLUSION: Health care professionals need to be aware of the ongoing psychological burden of celiac disease in order to support patients with this disease.

Citation

Zingone, F., Swift, G. L., Card, T. R., Sanders, D. S., Ludvigsson, J. F., & Bai, J. C. (2015). Psychological morbidity of celiac disease: a review of the literature. United European Gastroenterology Journal, 3(2), https://doi.org/10.1177/2050640614560786

• Journal Article Type: Article
• Acceptance Date: Oct 29, 2014
• Online Publication Date: Nov 28, 2014
• Publication Date: Apr 1, 2015
• Deposit Date: Aug 15, 2016
• Publicly Available Date: Aug 15, 2016
• Journal: United European Gastroenterology Journal
• Print ISSN: 2050-6406
• Electronic ISSN: 2050-6414
• Publisher: SAGE Publications
• Peer Reviewed: Peer Reviewed
• Volume: 3
• Issue: 2
• DOI: https://doi.org/10.1177/2050640614560786
• Keywords: anxiety, depression, fatigue, gluten, quality of life
• Public URL: https://nottingham-repository.worktribe.com/output/746149
• Related Public URLs: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406898/
• Contract Date: Aug 15, 2016