Outputs (21)

Prebiotic galactooligosaccharide feed modifies the chicken gut microbiota to efficiently clear Salmonella (2024)
Journal Article
Richards, P. J., Almutrafy, A., Liang, L., Flaujac Lafontaine, G. M., King, E., Fish, N. M., Connerton, A. J., Connerton, P. L., & Connerton, I. F. (2024). Prebiotic galactooligosaccharide feed modifies the chicken gut microbiota to efficiently clear Salmonella. mSystems, 9(8), Article e00754-24. https://doi.org/10.1128/msystems.00754-24

Chicken meat is contaminated with Salmonella from the gut of infected chickens during slaughter. Eradication of Salmonella from broiler chickens through hygiene measures and/or vaccination is not cost-effective; complementary approaches are required.... Read More about Prebiotic galactooligosaccharide feed modifies the chicken gut microbiota to efficiently clear Salmonella.

Food biotechnology (2020)
Journal Article
Foster, T., Adams, G., di Bari, V., Connerton, I., Gould, J., Gouseti, O., Gray, D., & Yakubov, G. (2020). Food biotechnology. Current Opinion in Chemical Engineering, 30, 53-59. https://doi.org/10.1016/j.coche.2020.08.006

We investigate recent advances in the Chemical Engineering aspects of food structuring agents and macronutrients: carbohydrates, proteins and lipids, and also the fate of food upon ingestion. Prebiotic effects on host-microbe interactions enable impr... Read More about Food biotechnology.

Phage control of Campylobacter jejuni in chickens does not produce collateral effects on the gut microbiota (2019)
Journal Article
Richards, P. J., Connerton, P. L., & Connerton, I. F. (2019). Phage control of Campylobacter jejuni in chickens does not produce collateral effects on the gut microbiota. Frontiers in Microbiology, 10, Article 476. https://doi.org/10.3389/fmicb.2019.00476

Bacteriophage biocontrol to reduce Campylobacter jejuni levels in chickens can reduce human exposure and disease acquired through the consumption of contaminated poultry products.Investigating changes in the chicken microbiota during phage treatment... Read More about Phage control of Campylobacter jejuni in chickens does not produce collateral effects on the gut microbiota.

FlhF(T368A) modulates motility in the bacteriophage carrier state of Campylobacter jejuni (2018)
Journal Article
Liang, L., & Connerton, I. F. (2018). FlhF(T368A) modulates motility in the bacteriophage carrier state of Campylobacter jejuni. Molecular Microbiology, 110(4), 616-633. https://doi.org/10.1111/mmi.14120

© 2018 The Authors. Molecular Microbiology Published by John Wiley & Sons Ltd. The carrier state is an alternative bacteriophage life cycle by which virulent bacteriophage can persist in association with host bacteria. Campylobacter jejuni carrier... Read More about FlhF(T368A) modulates motility in the bacteriophage carrier state of Campylobacter jejuni.

Bacteriophage ZCKP1: a potential treatment for Klebsiella pneumoniae isolated from diabetic foot patients (2018)
Journal Article
Taha, O. A., Connerton, P., Connerton, I., & El-Shibiny, A. (2018). Bacteriophage ZCKP1: a potential treatment for Klebsiella pneumoniae isolated from diabetic foot patients. Frontiers in Microbiology, 9, Article 2127. https://doi.org/10.3389/fmicb.2018.02127

The recorded growth in infection by multidrug resistant bacteria necessitates prompt efforts towards developing alternatives to antibiotics, such as bacteriophage therapy. Immuno-compromised patients with diabetes mellitus are particularly prone to f... Read More about Bacteriophage ZCKP1: a potential treatment for Klebsiella pneumoniae isolated from diabetic foot patients.

The effect of the timing of exposure to Campylobacter jejuni on the gut microbiome and inflammatory responses of broiler chickens (2018)
Journal Article
Connerton, P. L., Richards, P. J., Lafontaine, G. M., O'Kane, P. M., Ghaffar, N. M., Cummings, N. J., Smith, D. L., Fish, N. M., & Connerton, I. F. (in press). The effect of the timing of exposure to Campylobacter jejuni on the gut microbiome and inflammatory responses of broiler chickens. Microbiome, 6, Article 88. https://doi.org/10.1186/s40168-018-0477-5

Background
Campylobacters are an unwelcome member of the poultry gut microbiota in terms of food safety. The objective of this study was to compare the microbiota, inflammatory responses, and zootechnical parameters of broiler chickens not exposed t... Read More about The effect of the timing of exposure to Campylobacter jejuni on the gut microbiome and inflammatory responses of broiler chickens.

Characterisation of aerotolerant forms of a robust chicken colonizing Campylobacter coli (2017)
Journal Article
O'Kane, P. M., & Connerton, I. F. (in press). Characterisation of aerotolerant forms of a robust chicken colonizing Campylobacter coli. Frontiers in Microbiology, 8, https://doi.org/10.3389/fmicb.2017.00513

Campylobacter contaminated poultry meat is a major source of human foodborne illness. Campylobacter coli strain OR12 is a robust colonizer of chickens that was previously shown to outcompete and displace other Campylobacter strains from the chicken’s... Read More about Characterisation of aerotolerant forms of a robust chicken colonizing Campylobacter coli.

The minor flagellin of Campylobacter jejuni (FlaB) confers defensive properties against bacteriophage infection (2016)
Journal Article
Lis, L., & Connerton, I. F. (in press). The minor flagellin of Campylobacter jejuni (FlaB) confers defensive properties against bacteriophage infection. Frontiers in Microbiology, 7, https://doi.org/10.3389/fmicb.2016.01908

A screen of bacteriophages infecting a panel of Campylobacter jejuni PT14 gene knock-out mutants identified a role for the minor flagellin encoded by the flaB gene, in the defense of the host against CP8unalikevirus bacteriophage CP_F1 infection. Ina... Read More about The minor flagellin of Campylobacter jejuni (FlaB) confers defensive properties against bacteriophage infection.

Campylobacters and their bacteriophages from chicken liver: the prospect for phage biocontrol (2016)
Journal Article
Firlieyanti, A. S., Connerton, P. L., & Connerton, I. F. (2016). Campylobacters and their bacteriophages from chicken liver: the prospect for phage biocontrol. International Journal of Food Microbiology, 237, 121-127. https://doi.org/10.1016/j.ijfoodmicro.2016.08.026

Consumption of foods containing chicken liver has been associated with Campylobacter enteritis. Campylobacters can contaminate the surface of livers post-mortem but can also arise through systemic infection of colonising bacteria in live birds. The u... Read More about Campylobacters and their bacteriophages from chicken liver: the prospect for phage biocontrol.

The effect of thermal processing in oil on the macromolecular integrity and acrylamide formation from starch of three potato cultivars organically fertilized (2016)
Journal Article
Varzakas, T., Alghamdi, A., Alghamdi, H., Linforth, R. S., Dinu, V., Besong, T. D., Gillis, R. B., Adams, G. G., Arapoglou, D., Connerton, I. F., Harding, S. E., & Israilides, C. (2016). The effect of thermal processing in oil on the macromolecular integrity and acrylamide formation from starch of three potato cultivars organically fertilized. Cogent Food and Agriculture, 2(1), https://doi.org/10.1080/23311932.2016.1180950

Starches from three organically produced cultivars of potato tuber (Lady Rosetta, Spunta and Voyager) have been studied in relation to (i) acrylamide production (ii) macromolecular integrity after frying with extra virgin olive oil, soybean oil and c... Read More about The effect of thermal processing in oil on the macromolecular integrity and acrylamide formation from starch of three potato cultivars organically fertilized.