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Outputs (664)

Mathematical modelling of carbohydrate and protein metabolism in muscle (2025)
Journal Article
Alharbi, B. M., Williams, H. E., Parr, T., Brameld, J. M., Fallaize, C., & Wattis, J. A. (2025). Mathematical modelling of carbohydrate and protein metabolism in muscle. Mathematical Biosciences, 386, Article 109455. https://doi.org/10.1016/j.mbs.2025.109455

We propose a mathematical model based on coupled ordinary differential equations (ODEs) for metabolite concentrations with the aim of investigating how modifications to the rates affects outputs from a regulatory network. Our aim is to model the rela... Read More about Mathematical modelling of carbohydrate and protein metabolism in muscle.

Is There a Specific Role for Fungal Protein Within Food Based Dietary Guidelines? A Roundtable Discussion (2025)
Journal Article
Derbyshire, E. J., Brameld, J. M., Wall, B. T., Thomas, P., Arens, U., Forde, C. G., Hall, W., Glenn, A. J., Hill, T. R., & Paxman, J. (2025). Is There a Specific Role for Fungal Protein Within Food Based Dietary Guidelines? A Roundtable Discussion. Nutrition Bulletin, 1-15. https://doi.org/10.1111/nbu.70011

Expanding and aging populations, sustainability drivers and changing attitudes to the way we eat mean that there has been growing interest in non-animal derived protein food sources. Given this shift, there has been an uprise in consumer demand and c... Read More about Is There a Specific Role for Fungal Protein Within Food Based Dietary Guidelines? A Roundtable Discussion.

Evaluating the impact of simulated microgravity of a Random Positioning Machine on the stability of emulsions applying scaling analysis via dimensionless numbers (2025)
Preprint / Working Paper
Schmidt, S., Adebowale, M. N., Rebrov, E., Fisk, I., Yang, N., Saarela, M., & Hessel, V. (2025). Evaluating the impact of simulated microgravity of a Random Positioning Machine on the stability of emulsions applying scaling analysis via dimensionless numbers

Random Positioning Machines (RPM) are commonly used to simulate microgravity for plant growth and cell culturing experiments, but not properly in multi-phase flow studies, e.g., emulsions. The implications of fluid motion induced by RPM movement patt... Read More about Evaluating the impact of simulated microgravity of a Random Positioning Machine on the stability of emulsions applying scaling analysis via dimensionless numbers.

TMT-based quantitative proteomic assessment of Vicia sativa induced neurotoxicity by β-cyano-L-alanine and γ-glutamyl-β-cyano-L-alanine in SH-SY5Y cells (2025)
Preprint / Working Paper
Riley, S., Nguyen, V., Bhattacharjee, R., Ng, P. Q., Ritchie, T., Fisk, I., Gecz, J., Kumar, R., & Searle, I. R. (2025). TMT-based quantitative proteomic assessment of Vicia sativa induced neurotoxicity by β-cyano-L-alanine and γ-glutamyl-β-cyano-L-alanine in SH-SY5Y cells

β-Cyano-L-alanine (BCA) and γ-glutamyl-β-cyano-L-alanine (GBCA) are the primary antinutritional compounds present within the seeds of the high protein and drought tolerant orphan legume Vicia sativa. Evidence of neurotoxicity is limited to symptom an... Read More about TMT-based quantitative proteomic assessment of Vicia sativa induced neurotoxicity by β-cyano-L-alanine and γ-glutamyl-β-cyano-L-alanine in SH-SY5Y cells.

Octopamine alters yellow mealworm body composition (2025)
Journal Article
Hill, V., Williams, L., Salter, A., Brameld, J., & Parr, T. (2025). Octopamine alters yellow mealworm body composition. Animal, 19(5), Article 101490. https://doi.org/10.1016/j.animal.2025.101490

There is the potential to increase the production yield within the emerging insect industry in order to produce high-quality, sustainable protein. In invertebrates, the monoamine, octopamine (OA), has a similar role to that of noradrenaline in mammal... Read More about Octopamine alters yellow mealworm body composition.

Safety, Feasibility, and Effectiveness of Ketogenic Diet in Pediatric Patients With Brain Tumors: A Systematic Review (2025)
Journal Article
AlMutairi, H., Mccullough, F., Siddiqui, K., Ghemlas, I., AlHarbi, M., Grundy, R., & Dandapani, M. (2025). Safety, Feasibility, and Effectiveness of Ketogenic Diet in Pediatric Patients With Brain Tumors: A Systematic Review. Journal of Nutrition and Metabolism, https://doi.org/10.1155/jnme/7935879

Background: Evidence suggests the positive effects of ketogenic diet (KD) on cancers by limiting glucose availability to cancer cells. This systematic review aimed to explore the safety, feasibility, and effectiveness of KD in children with brain tum... Read More about Safety, Feasibility, and Effectiveness of Ketogenic Diet in Pediatric Patients With Brain Tumors: A Systematic Review.

Food insecurity amongst universal credit claimants: the benefits and nutrition study (BEANS), a cross-sectional online study (2025)
Journal Article
Thomas, M., Rose, P., Coneyworth, L., Harvey, J., Goulding, J., Stone, J., Padley, M., O’Reilly, P., & Welham, S. (2025). Food insecurity amongst universal credit claimants: the benefits and nutrition study (BEANS), a cross-sectional online study. European Journal of Nutrition, 64, Article 115. https://doi.org/10.1007/s00394-025-03596-y

Purpose
Increasing food insecurity (FIS) in the UK presents a major challenge to public health. Universal Credit (UC) claimants are disproportionately impacted by FIS but research on socio-demographic factors and consequent nutritional security is... Read More about Food insecurity amongst universal credit claimants: the benefits and nutrition study (BEANS), a cross-sectional online study.

The anti-inflammatory effects of vitamin D on offspring brain development during pregnancy: critical review (2025)
Journal Article
Kozhevnikova, S. V., Elmes, M. J., Brameld, J. M., & Jethwa, P. H. (in press). The anti-inflammatory effects of vitamin D on offspring brain development during pregnancy: critical review. Academia, Nutrition and Dietetics, 2(1), Article 7573. https://doi.org/10.20935/acadnutr7573

Vitamin D (VD) plays a pivotal role in fetal brain development by regulating essential processes such as neuronal proliferation, differentiation, and apoptosis. Despite the critical role of VD in maternal and fetal health, studies have shown that alm... Read More about The anti-inflammatory effects of vitamin D on offspring brain development during pregnancy: critical review.