Outputs (609)

Assessing Water Content of the Human Colonic Chyme Using the MRI Parameter T1: A Key Biomarker of Colonic Function (2025)
Journal Article
Dellschaft, N., Murray, K., Ren, Y., Marciani, L., Gowland, P., Spiller, R., & Hoad, C. (2025). Assessing Water Content of the Human Colonic Chyme Using the MRI Parameter T1: A Key Biomarker of Colonic Function. Neurogastroenterology and Motility, https://doi.org/10.1111/nmo.14999

Background
The human colon receives 2 L of fluid daily. Small changes in the efficacy of absorption can lead to altered stool consistency with diarrhea or constipation. Drugs and formulations can also alter colonic water, which can be assessed using... Read More about Assessing Water Content of the Human Colonic Chyme Using the MRI Parameter T1: A Key Biomarker of Colonic Function.

Mode of Action of Psyllium in Reducing Gas Production from Inulin and its Interaction with Colonic Microbiota: A 24 hours, Randomised, Placebo-Controlled Trial in Healthy Human Volunteers (2024)
Journal Article
Alhasani, A., Modasia, A., Anodiyil, M., Corsetti, M., Aliyu, A., Crooks, C., MARCIANI, L., Reid, J., Yakubov, G., Avery, A., Harris, H., Warren, F., & Spiller, R. (2024). Mode of Action of Psyllium in Reducing Gas Production from Inulin and its Interaction with Colonic Microbiota: A 24 hours, Randomised, Placebo-Controlled Trial in Healthy Human Volunteers. Journal of Nutrition, https://doi.org/10.1016/j.tjnut.2024.12.017

Background: Recent studies show that the increase in breath hydrogen (BH2) and symptoms after ingestion of inulin is reduced by co-administering psyllium.

Objectives: To determine if slowing delivery of inulin to the colon by administering it in... Read More about Mode of Action of Psyllium in Reducing Gas Production from Inulin and its Interaction with Colonic Microbiota: A 24 hours, Randomised, Placebo-Controlled Trial in Healthy Human Volunteers.

Mineral Supplements in Aging (2024)
Book Chapter
Welham, S., Rose, P., Coneyworth, L., Avery, A., & Kirk, C. (2024). Mineral Supplements in Aging. In V. I. Korolchuk, & J. R. Harris (Eds.), Biochemistry and Cell Biology of Ageing: Part V, Anti-ageing Interventions (269-306). Springer Nature

With advancing age, achievement of dietary adequacy for all nutrients is increasingly difficult and this is particularly so for minerals. Various factors impede mineral acquisition and absorption including reduced appetite, depressed gastric acid pro... Read More about Mineral Supplements in Aging.

The food and nutritional insecurity experienced by pregnant women living in shelters following the 2023 earthquakes in Turkiye (2024)
Journal Article
Kaçar, H. K., Kaçar, Ö. F., Kose, T., & Avery, A. (2024). The food and nutritional insecurity experienced by pregnant women living in shelters following the 2023 earthquakes in Turkiye. International Journal of Disaster Risk Reduction, 114, Article 104987. https://doi.org/10.1016/j.ijdrr.2024.104987

Natural hazards may limit household access to food and water. Shelters and food aid were provided as emergency measures following the 2023 earthquakes (EQ) in Turkiye. Pregnancy is a nutritionally vulnerable time. This study investigated weight chang... Read More about The food and nutritional insecurity experienced by pregnant women living in shelters following the 2023 earthquakes in Turkiye.

Rapeseed oleosomes facilitate intestinal lymphatic delivery and oral bioavailability of cannabidiol (2024)
Journal Article
Ji, L., Feng, W., Chen, H., Chu, Y., Wong, A., Zhu, Y., Sinatra, G., Bramante, F., Carrière, F., Stocks, M. J., di Bari, V., Gray, D. A., & Gershkovich, P. (2025). Rapeseed oleosomes facilitate intestinal lymphatic delivery and oral bioavailability of cannabidiol. International Journal of Pharmaceutics, 668, Article 124947. https://doi.org/10.1016/j.ijpharm.2024.124947

Due to high lipophilicity and extensive first-pass metabolic loss, cannabidiol (CBD) has low oral bioavailability. Co-administration of CBD and long-chain lipids facilitates the intestinal lymphatic delivery, resulting in higher systemic bioavailabil... Read More about Rapeseed oleosomes facilitate intestinal lymphatic delivery and oral bioavailability of cannabidiol.

Association between glucagon-like peptide-1 receptor agonists use and change in alcohol consumption: a systematic review (2024)
Journal Article
Subhani, M., Dhanda, A., King, J. A., Warren, F. C., Creanor, S., Davies, M. J., Eldeghaidy, S., Bawden, S., Gowland, P. A., Bataller, R., Greenwood, J., Kaar, S., Bhala, N., & Aithal, G. P. (2024). Association between glucagon-like peptide-1 receptor agonists use and change in alcohol consumption: a systematic review. eClinicalMedicine, 78, Article 102920. https://doi.org/10.1016/j.eclinm.2024.102920

Background
Despite the availability of various pharmacological and behavioural interventions, alcohol-related mortality is rising. This systematic review aimed to critically evaluate the existing literature on the association between glucagon-like p... Read More about Association between glucagon-like peptide-1 receptor agonists use and change in alcohol consumption: a systematic review.

Mechanisms of aroma compound formation during the drying of Dendrobium nobile stems (Shihu) (2024)
Journal Article
Kirkwood, A., Fisk, I., Xu, Y., Reid, J., & Yang, N. (2025). Mechanisms of aroma compound formation during the drying of Dendrobium nobile stems (Shihu). Food Chemistry, 464, Part 3, Article 141888. https://doi.org/10.1016/j.foodchem.2024.141888

To ensure the aroma and flavour quality of dried herbs, it is essential to understand flavour reactions that occur during complex drying mechanisms. This study investigated aroma formation in dried Dendrobium nobile stems (Shihu), valued in Chinese c... Read More about Mechanisms of aroma compound formation during the drying of Dendrobium nobile stems (Shihu).

Cosmic-Ray Radiation Effects on Ibuprofen Tablet Formulation Inside and Outside of the International Space Station (2024)
Journal Article
Tran, Q. D., Spooner, N., Geoghehan, S., Thavarajah, S. R., Rahman, S., Tran, N. N., Williams, P. M., Jarquin, S. M., Kim, D., Davey, K., Buell, J., Shumbera, M., Gittleman, M., Clements, T., Stoudemire, J., Fisk, I., & Hessel, V. (2024). Cosmic-Ray Radiation Effects on Ibuprofen Tablet Formulation Inside and Outside of the International Space Station. Advanced Healthcare Materials, https://doi.org/10.1002/adhm.202402361

In extreme environments people will have different needs for medicine(s), making it crucial to understand how such environments affect drug efficacy. Ibuprofen, commonly used in tablet formulation on Earth, could fail in space despite standard pharma... Read More about Cosmic-Ray Radiation Effects on Ibuprofen Tablet Formulation Inside and Outside of the International Space Station.

Cosmic-Ray Radiation Effects on Ibuprofen Tablet Formulation Inside and Outside of the International Space Station (2024)
Preprint / Working Paper
Fisk, I., Tran, Q., Spooner, N., Geoghehan, S., Thavarajah, S., Rahman, S., Tran, N., Williams, P., Jarquin, S., Kim, D.-H., Davey, K., Buell, J., Shumbera, M., Gittleman, M., Clements, T., Stoudemire, J., & Hessel, V. (2024). Cosmic-Ray Radiation Effects on Ibuprofen Tablet Formulation Inside and Outside of the International Space Station

In extreme environments people will have different needs for medicine(s). It is important, therefore, to know how medicine efficacy will be impacted by the environment. Ibuprofen is very widely used in tablet formulation in temperate climates on Eart... Read More about Cosmic-Ray Radiation Effects on Ibuprofen Tablet Formulation Inside and Outside of the International Space Station.

Development of analytical “aroma wheels” for Oolong tea infusions (Shuixian and Rougui) and prediction of dynamic aroma release and colour changes during “Chinese tea ceremony” with machine learning (2024)
Journal Article
Yang, N., Simon, J., Fang, W., Ayed, C., Zhang, W. E., Axell, M., Viltoriano, R., & Fisk, I. (2025). Development of analytical “aroma wheels” for Oolong tea infusions (Shuixian and Rougui) and prediction of dynamic aroma release and colour changes during “Chinese tea ceremony” with machine learning. Food Chemistry, 464, Article 141537. https://doi.org/10.1016/j.foodchem.2024.141537

The flavour of tea as a worldwide popular beverage has been studied extensively. This study aimed to apply established flavour analysis techniques (GC–MS, GC-O-MS and APCI-MS/MS) in innovative ways to characterise the flavour profile of oolong tea in... Read More about Development of analytical “aroma wheels” for Oolong tea infusions (Shuixian and Rougui) and prediction of dynamic aroma release and colour changes during “Chinese tea ceremony” with machine learning.