Outputs (516)

Altered connectivity of the right anterior insula drives the pain connectome changes in chronic knee osteoarthritis (2018)
Journal Article
Cottam, W. J., Iwabuchi, S. J., Drabek, M. M., Reckziegel, D., & Auer, D. P. (2018). Altered connectivity of the right anterior insula drives the pain connectome changes in chronic knee osteoarthritis. PAIN, 159(5), https://doi.org/10.1097/j.pain.0000000000001209

Resting-state functional connectivity (FC) has proven a powerful approach to understand the neural underpinnings of chronic pain, reporting altered connectivity in three main networks: the default mode (DMN), central executive (CEN), and the salience... Read More about Altered connectivity of the right anterior insula drives the pain connectome changes in chronic knee osteoarthritis.

The Physiological Bases of Hidden Noise-Induced Hearing Loss: Protocol for a Functional Neuroimaging Study (2018)
Journal Article
Dewey, R. S., Hall, D. A., Guest, H., Prendergast, G., Plack, C. J., & Francis, S. T. (2018). The Physiological Bases of Hidden Noise-Induced Hearing Loss: Protocol for a Functional Neuroimaging Study. JMIR Research Protocols, 7(3), Article e79. https://doi.org/10.2196/resprot.9095

Background: Rodent studies indicate that noise exposure can cause permanent damage to synapses between inner hair cells and high-threshold auditory nerve fibers, without permanently altering threshold sensitivity. These demonstrations of what is comm... Read More about The Physiological Bases of Hidden Noise-Induced Hearing Loss: Protocol for a Functional Neuroimaging Study.

Altered temporal stability in dynamic neural networks underlies connectivity changes in neurodevelopment (2018)
Journal Article
Brookes, M. J., Groom, M. J., Liuzzi, L., Hill, R. M., Smith, H. J., Briley, P. M., Hall, E. L., Hunt, B. A., Gascoyne, L. E., Taylor, M. J., Liddle, P. F., Morris, P. G., Woolrich, M. W., & Liddle, E. B. (2018). Altered temporal stability in dynamic neural networks underlies connectivity changes in neurodevelopment. NeuroImage, 174, https://doi.org/10.1016/j.neuroimage.2018.03.008

Network connectivity is an integral feature of human brain function, and characterising its maturational trajectory is a critical step towards understanding healthy and atypical neurodevelopment. Here, we used magnetoencephalography (MEG) to investig... Read More about Altered temporal stability in dynamic neural networks underlies connectivity changes in neurodevelopment.

Exploring the origins of EEG motion artefacts during simultaneous fMRI acquisition: implications for motion artefact correction (2018)
Journal Article
Spencer, G. S., Smith, J. A., Chowdhury, M. E., Bowtell, R. W., & Mullinger, K. J. (in press). Exploring the origins of EEG motion artefacts during simultaneous fMRI acquisition: implications for motion artefact correction. NeuroImage, 173, https://doi.org/10.1016/j.neuroimage.2018.02.034

Motion artefacts (MAs) are induced within EEG data collected simultaneously with fMRI when the subject’s head rotates relative to the magnetic field. The effects of these artefacts have generally been ameliorated by removing periods of data during wh... Read More about Exploring the origins of EEG motion artefacts during simultaneous fMRI acquisition: implications for motion artefact correction.

A biophysical model of dynamic balancing of excitation and inhibition in fast oscillatory large-scale networks (2018)
Journal Article
Abeysuriya, R. G., Hadida, J., Sotiropoulos, S. N., Jbabdi, S., Becker, R., Hunt, B. A., Brookes, M. J., & Woolrich, M. W. (in press). A biophysical model of dynamic balancing of excitation and inhibition in fast oscillatory large-scale networks. PLoS Computational Biology, 14(2), Article e1006007. https://doi.org/10.1371/journal.pcbi.1006007

Over long timescales, neuronal dynamics can be robust to quite large perturbations, such as changes in white matter connectivity and grey matter structure through processes including learning, aging, development and certain disease processes. One pos... Read More about A biophysical model of dynamic balancing of excitation and inhibition in fast oscillatory large-scale networks.

Effects of sprint interval training on ectopic lipids and tissue-specific insulin sensitivity in men with non-alcoholic fatty liver disease (2018)
Journal Article
Sargeant, J. A., Bawden, S., Aithal, G. P., Simpson, E. J., Macdonald, I. A., Turner, M. C., Cegielski, J., Smith, K., Dorling, J. L., Gowland, P. A., Nimmo, M. A., & King, J. A. (2018). Effects of sprint interval training on ectopic lipids and tissue-specific insulin sensitivity in men with non-alcoholic fatty liver disease. European Journal of Applied Physiology, 118(4), 817-828. https://doi.org/10.1007/s00421-018-3818-y

Purpose: This study examined the feasibility of sprint interval exercise training (SIT) for men with non-alcoholic fatty liver disease (NAFLD) and its effects on intrahepatic triglyceride (IHTG), insulin sensitivity (hepatic and peripheral), visceral... Read More about Effects of sprint interval training on ectopic lipids and tissue-specific insulin sensitivity in men with non-alcoholic fatty liver disease.

Cortical differences in diverticular disease and correlation with symptom reports (2018)
Journal Article
Pitiot, A., Smith, J. K., Garratt, J., Francis, S. T., Gowland, P. A., Spiller, R. C., & Marciani, L. (2018). Cortical differences in diverticular disease and correlation with symptom reports. Neurogastroenterology and Motility, 30(7), Article e13303. https://doi.org/10.1111/nmo.13303

Background

Recent studies have shown that the brain of patients with gastrointestinal disease differ both structurally and functionally from that of controls. Highly somatizing diverticular disease (HSDD) patients were also shown to differ from l... Read More about Cortical differences in diverticular disease and correlation with symptom reports.

Variation in thermally induced taste response across thermal tasters (2018)
Journal Article
Skinner, M., Eldeghaidy, S., Ford, R., Giesbrecht, T., Thomas, A., Francis, S., & Hort, J. (2018). Variation in thermally induced taste response across thermal tasters. Physiology and Behavior, 188, 67-78. https://doi.org/10.1016/j.physbeh.2018.01.017

Thermal tasters (TTs) perceive thermally induced taste (thermal taste) sensations when the tongue is stimulated with temperature in the absence of gustatory stimuli, while thermal non tasters (TnTs) only perceive temperature. This is the first study... Read More about Variation in thermally induced taste response across thermal tasters.

Does tranexamic acid lead to changes in MRI-measures of brain tissue health in patients with spontaneous intracerebral haemorrhage? An MRI sub-study nested within the double-blind randomised controlled TICH-2 trial (2018)
Journal Article
Dineen, R. A., Pszczolkowski, S., Flaherty, K., Law, Z. K., Morgan, P. S., Roberts, I., Werring, D., Al-Shahi Salman, R., England, T. J., Bath, P. M., & Sprigg, N. (in press). Does tranexamic acid lead to changes in MRI-measures of brain tissue health in patients with spontaneous intracerebral haemorrhage? An MRI sub-study nested within the double-blind randomised controlled TICH-2 trial. BMJ Open, 8(2), Article e019930. https://doi.org/10.1136/bmjopen-2017-019930

Objectives: To test whether administration of the antifibrinolytic drug tranexamic acid (TXA) in patients with spontaneous intracerebral haemorrhage (SICH) leads to increased prevalence of diffusion-weighted MRI defined hyperintense ischaemic lesions... Read More about Does tranexamic acid lead to changes in MRI-measures of brain tissue health in patients with spontaneous intracerebral haemorrhage? An MRI sub-study nested within the double-blind randomised controlled TICH-2 trial.

Neural circuitry underlying sustained attention in healthy adolescents and in ADHD symptomatology (2017)
Journal Article
O'Halloran, L., Cao, Z., Ruddy, K., Jollans, L., Albaugh, M. D., Aleni, A., Potter, A. S., Vahey, N., Banaschewski, T., Hohmann, S., Bokde, A. L., Bromberg, U., Büchel, C., Quinlan, E. B., Desrivières, S., Flor, H., Frouin, V., Gowland, P. A., Heinz, A., Ittermann, B., …Whelan, R. (2018). Neural circuitry underlying sustained attention in healthy adolescents and in ADHD symptomatology. NeuroImage, 169, https://doi.org/10.1016/j.neuroimage.2017.12.030

Moment-to-moment reaction time variability on tasks of attention, often quantified by intra-individual response variability (IRV), provides a good indication of the degree to which an individual is vulnerable to lapses in sustained attention. Increa... Read More about Neural circuitry underlying sustained attention in healthy adolescents and in ADHD symptomatology.