Outputs (516)

Fast and High‐Resolution T2 Mapping Based on Echo Merging Plus k‐t Undersampling with Reduced Refocusing Flip Angles (TEMPURA) as Methods for Human Renal MRI (2024)
Journal Article
Li, H., Priest, A. N., Horvat‐Menih, I., Huang, Y., Li, S., Stewart, G. D., Mendichovszky, I. A., Francis, S. T., & Gallagher, F. A. (2024). Fast and High‐Resolution T2 Mapping Based on Echo Merging Plus k‐t Undersampling with Reduced Refocusing Flip Angles (TEMPURA) as Methods for Human Renal MRI. Magnetic Resonance in Medicine, 92(3), 1138-1148. https://doi.org/10.1002/mrm.30115

Purpose: To develop a highly accelerated multi‐echo spin‐echo method, TEMPURA, for reducing the acquisition time and/or increasing spatial resolution for kidney T2 mapping. Methods: TEMPURA merges several adjacent echoes into one k‐space by either co... Read More about Fast and High‐Resolution T2 Mapping Based on Echo Merging Plus k‐t Undersampling with Reduced Refocusing Flip Angles (TEMPURA) as Methods for Human Renal MRI.

Post‐task responses following working memory and movement are driven by transient spectral bursts with similar characteristics (2024)
Journal Article
Coleman, S. C., Seedat, Z. A., Pakenham, D. O., Quinn, A. J., Brookes, M. J., Woolrich, M. W., & Mullinger, K. J. (2024). Post‐task responses following working memory and movement are driven by transient spectral bursts with similar characteristics. Human Brain Mapping, 45(7), Article e26700. https://doi.org/10.1002/hbm.26700

The post-movement beta rebound has been studied extensively using magnetoencephalography (MEG) and is reliably modulated by various task parameters as well as illness. Our recent study showed that rebounds, which we generalise as “post-task responses... Read More about Post‐task responses following working memory and movement are driven by transient spectral bursts with similar characteristics.

Isocitrate Dehydrogenase 1/2 Wildtype Adult Astrocytoma with WHO Grade 2/3 Histological Features: Molecular Re-Classification, Prognostic Factors, Clinical Outcomes (2024)
Journal Article
Gupta, M., Anjari, M., Brandner, S., Fersht, N., Wilson, E., Thust, S., & Kosmin, M. (2024). Isocitrate Dehydrogenase 1/2 Wildtype Adult Astrocytoma with WHO Grade 2/3 Histological Features: Molecular Re-Classification, Prognostic Factors, Clinical Outcomes. Biomedicines, 12(4), Article 901. https://doi.org/10.3390/biomedicines12040901

Background: Isocitrate Dehydrogenase 1/2 (IDH 1/2)-wildtype (WT) astrocytomas constitute a heterogeneous group of tumors and have undergone a series of diagnostic reclassifications over time. This study aimed to investigate molecular markers, clinica... Read More about Isocitrate Dehydrogenase 1/2 Wildtype Adult Astrocytoma with WHO Grade 2/3 Histological Features: Molecular Re-Classification, Prognostic Factors, Clinical Outcomes.

Recommendations for quantitative cerebral perfusion MRI using multi‐timepoint arterial spin labeling: Acquisition, quantification, and clinical applications (2024)
Journal Article
Woods, J. G., Achten, E., Asllani, I., Bolar, D. S., Dai, W., Detre, J. A., Fan, A. P., Fernández‐Seara, M. A., Golay, X., Günther, M., Guo, J., Hernandez‐Garcia, L., Ho, M., Juttukonda, M. R., Lu, H., MacIntosh, B. J., Madhuranthakam, A. J., Mutsaerts, H., Okell, T. W., Parkes, L. M., …the ISMRM Perfusion Study Group. (2024). Recommendations for quantitative cerebral perfusion MRI using multi‐timepoint arterial spin labeling: Acquisition, quantification, and clinical applications. Magnetic Resonance in Medicine, 92(2), 469-495. https://doi.org/10.1002/mrm.30091

Accurate assessment of cerebral perfusion is vital for understanding the hemodynamic processes involved in various neurological disorders and guiding clinical decision-making. This guidelines article provides a comprehensive overview of quantitative... Read More about Recommendations for quantitative cerebral perfusion MRI using multi‐timepoint arterial spin labeling: Acquisition, quantification, and clinical applications.

Effects of the Fasting‐Postprandial State on Arterial Spin Labeling MRI‐Based Cerebral Perfusion Quantification in Alzheimer's Disease (2024)
Journal Article
Li, R., Zhuo, Z., Hong, Y., Yao, Z., Li, Z., Wang, Y., Jiang, J., Wang, L., Jia, Z., Sun, M., Zhang, Y., Li, W., Ren, Q., Zhang, Y., Duan, Y., Liu, Y., Wei, H., Zhang, Y., Chappell, M., Shi, H., …Xu, J. (2024). Effects of the Fasting‐Postprandial State on Arterial Spin Labeling MRI‐Based Cerebral Perfusion Quantification in Alzheimer's Disease. Journal of Magnetic Resonance Imaging, 60(5), 2173-2183. https://doi.org/10.1002/jmri.29348

Background
The fasting-postprandial state remains an underrecognized confounding factor for quantifying cerebral blood flow (CBF) in the cognitive assessment and differential diagnosis of Alzheimer's disease (AD).

Purpose
To investigate the effe... Read More about Effects of the Fasting‐Postprandial State on Arterial Spin Labeling MRI‐Based Cerebral Perfusion Quantification in Alzheimer's Disease.

Light Cannabis Use and the Adolescent Brain: An 8-years Longitudinal Assessment of Mental Health, Cognition, and Reward Processing. (2024)
Journal Article
Macedo, I., Paiva, T. O., Pasion, R., Daedelow, L., Heinz, A., Magalhães, A., Banaschewski, T., Bokde, A. L., Desrivières, S., Flor, H., Grigis, A., Garavan, H., Gowland, P., Brühl, R., Martinot, J.-L., Martinot, M.-L. P., Artiges, E., Nees, F., Orfanos, D. P., Paus, T., …Barbosa, F. (2024). Light Cannabis Use and the Adolescent Brain: An 8-years Longitudinal Assessment of Mental Health, Cognition, and Reward Processing. Psychopharmacology, 241, 1447-1461. https://doi.org/10.1007/s00213-024-06575-z

Rationale: For decades, cannabis has been the most widely used illicit substance in the world, particularly among youth. Research suggests that mental health problems associated with cannabis use may result from its effect on reward brain circuit, em... Read More about Light Cannabis Use and the Adolescent Brain: An 8-years Longitudinal Assessment of Mental Health, Cognition, and Reward Processing..

Bayesian Inference for Non-linear forward model by using a VAE-based neural network structure (2024)
Journal Article
Zhang, Y., Zheng, J.-Q., & Chappell, M. (2024). Bayesian Inference for Non-linear forward model by using a VAE-based neural network structure. IEEE Transactions on Signal Processing, 72, 1400-1411. https://doi.org/10.1109/TSP.2024.3374115

In this paper, a Variational Autoencoder (VAE) based framework is introduced to solve parameter estimation problems for non-linear forward models. In particular, we focus on applications in the field of medical imaging where many thousands of model-b... Read More about Bayesian Inference for Non-linear forward model by using a VAE-based neural network structure.

Use of Magnetic Resonance Imaging for Visualization of Oral Dosage Forms in the Human Stomach: A Scoping Review (2024)
Journal Article
Akbar, T., Gershkovich, P., Stamatopoulos, K., Gowland, P. A., Stolnik, S., Butler, J., & Marciani, L. (2024). Use of Magnetic Resonance Imaging for Visualization of Oral Dosage Forms in the Human Stomach: A Scoping Review. Molecular Pharmaceutics, 21(4), 1553-1562. https://doi.org/10.1021/acs.molpharmaceut.3c01123

Oral dosage forms are the most widely and frequently used formulations to deliver active pharmaceutical ingredients (APIs), due to their ease of administration and noninvasiveness. Knowledge of intragastric release rates and gastric mixing is crucial... Read More about Use of Magnetic Resonance Imaging for Visualization of Oral Dosage Forms in the Human Stomach: A Scoping Review.

A preliminary study of dynamic neurochemical changes in the dorsolateral prefrontal cortex during working memory (2024)
Journal Article
Oh, H., Berrington, A., Auer, D. P., Babourina-Brooks, B., Faas, H., & Jung, J. Y. (2024). A preliminary study of dynamic neurochemical changes in the dorsolateral prefrontal cortex during working memory. European Journal of Neuroscience, 59(8), 2075-2086. https://doi.org/10.1111/ejn.16280

Working memory (WM) is one of the fundamental cognitive functions associated with the dorsolateral prefrontal cortex (DLPFC). However, the neurochemical mechanisms of WM, including the dynamic changes in neurometabolites such as glutamate and GABA in... Read More about A preliminary study of dynamic neurochemical changes in the dorsolateral prefrontal cortex during working memory.

Generalising XTRACT tractography protocols across common macaque brain templates (2024)
Journal Article
Assimopoulos, S., Warrington, S., Bryant, K. L., Pszczolkowski, S., Jbabdi, S., Mars, R. B., & Sotiropoulos, S. N. (2024). Generalising XTRACT tractography protocols across common macaque brain templates. Brain Structure and Function, 229, 1873-1888. https://doi.org/10.1007/s00429-024-02760-0

Non-human primates are extensively used in neuroscience research as models of the human brain, with the rhesus macaque being a prominent example. We have previously introduced a set of tractography protocols (XTRACT) for reconstructing 42 correspondi... Read More about Generalising XTRACT tractography protocols across common macaque brain templates.