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Outputs (516)

Colonic response to laxative ingestion as assessed by MRI differs in constipated irritable bowel syndrome compared to functional constipation (2016)
Journal Article
Lam, C., Chaddock, G., Marciani, L., Costigan, C., Paul, J., Cox, E., Hoad, C., Menys, A., Pritchard, S. E., Garsed, K., Taylor, S., Atkinson, D., Gowland, P. A., & Spiller, R. C. (2016). Colonic response to laxative ingestion as assessed by MRI differs in constipated irritable bowel syndrome compared to functional constipation. Neurogastroenterology and Motility, 28(6), https://doi.org/10.1111/nmo.12784

Background

Functional constipation (FC) and irritable bowel syndrome with constipation (IBS-C) share many symptoms but underlying mechanisms may be different. We have developed a magnetic resonance imaging (MRI) technique to measure intestinal vol... Read More about Colonic response to laxative ingestion as assessed by MRI differs in constipated irritable bowel syndrome compared to functional constipation.

Development and validation of a large, modular test meal with liquid and solid components for assessment of gastric motor and sensory function by non-invasive imaging (2016)
Journal Article
Parker, H. L., Tucker, E., Hoad, C., Pal, A., Costigan, C., Hudders, N., Perkins, A., Blackshaw, E., Gowland, P., Marciani, L., & Fox, M. R. (2016). Development and validation of a large, modular test meal with liquid and solid components for assessment of gastric motor and sensory function by non-invasive imaging. Neurogastroenterology and Motility, 28(4), 554-568. https://doi.org/10.1111/nmo.12752

Background: Current investigations of stomach function are based on small test meals that do not reliably induce symptoms and analysis techniques that rarely detect clinically relevant dysfunction. This study introduces the large ‘Nottingham Test Mea... Read More about Development and validation of a large, modular test meal with liquid and solid components for assessment of gastric motor and sensory function by non-invasive imaging.

Abnormal salience signaling in schizophrenia: The role of integrative beta oscillations: Salience Signaling in Schizophrenia (2016)
Journal Article
Liddle, E. B., Price, D., Palaniyappan, L., Brookes, M. J., Robson, S. E., Hall, E. L., Morris, P. G., & Liddle, P. F. (2016). Abnormal salience signaling in schizophrenia: The role of integrative beta oscillations: Salience Signaling in Schizophrenia. Human Brain Mapping, 37(4), 1361-1374. https://doi.org/10.1002/hbm.23107

Aberrant salience attribution and cerebral dysconnectivity both have strong evidential support as core dysfunctions in schizophrenia. Aberrant salience arising from an excess of dopamine activity has been implicated in delusions and hallucinations, e... Read More about Abnormal salience signaling in schizophrenia: The role of integrative beta oscillations: Salience Signaling in Schizophrenia.

Predicting haemodynamic networks using electrophysiology: The role of non-linear and cross-frequency interactions (2016)
Journal Article
Tewarie, P. K., Bright, M. G., Hillebrand, A., Robson, S. E., Gascoyne, L. E., Morris, P. G., Meier, J., Van Mieghem, P., & Brookes, M. J. (2016). Predicting haemodynamic networks using electrophysiology: The role of non-linear and cross-frequency interactions. NeuroImage, 130, https://doi.org/10.1016/j.neuroimage.2016.01.053

Understanding the electrophysiological basis of resting state networks (RSNs) in the human brain is a critical step towards elucidating how inter-areal connectivity supports healthy brain function. In recent years, the relationship between RSNs (typi... Read More about Predicting haemodynamic networks using electrophysiology: The role of non-linear and cross-frequency interactions.

Magnetic Resonance Spectroscopy discriminates the response to microglial stimulation of wild type and Alzheimer's disease models (2016)
Journal Article
Pardon, M.-C., Yanez Lopez, M., Yuchun, D., Bai, L., Marjańska, M., Brignell, C., Prior, M., Brignell, C., Parhizkar, S., Agostini, A., Auer, D. P., & Faas, H. M. (2016). Magnetic Resonance Spectroscopy discriminates the response to microglial stimulation of wild type and Alzheimer's disease models. Scientific Reports, 6, 1-12. https://doi.org/10.1038/srep19880

Statistics of highly heterogeneous flow fields confined to three-dimensional random porous media (2016)
Journal Article
Jin, C., Langston, P. A., Pavlovskaya, G. E., Hall, M. R., & Rigby, S. P. (2016). Statistics of highly heterogeneous flow fields confined to three-dimensional random porous media. Physical Review E, 93(1), 1-10. https://doi.org/10.1103/PhysRevE.93.013122

© 2016 authors. Published by the American Physical Society. Published by the American Physical Society under the terms of the Creative Commons Attribution 3.0 License. Further distribution of this work must maintain attribution to the author(s) and t... Read More about Statistics of highly heterogeneous flow fields confined to three-dimensional random porous media.

Effect of head pitch and roll orientations on magnetically induced vertigo (2015)
Journal Article
Mian, O. S., GLOVER, P., Li, Y., Antunes, A., & Day, B. L. (2016). Effect of head pitch and roll orientations on magnetically induced vertigo. Journal of Physiology, 594(4), 1051-1067. https://doi.org/10.1113/JP271513

High strength static magnetic fields are known to induce vertigo, believed to be via stimulation of the vestibular system. The leading hypothesis (Lorentz forces) predicts that the induced vertigo should depend on the orientation of the magnetic fiel... Read More about Effect of head pitch and roll orientations on magnetically induced vertigo.

Colon wall motility: comparison of novel quantitative semi-automatic measurements using cine MRI (2015)
Journal Article
Hoad, C., Menys, A., Garsed, K., Marciani, L., Hamy, V., Murray, K., Costigan, C., Atkinson, D., Major, G., Spiller, R. C., Taylor, S., & Gowland, P. A. (2016). Colon wall motility: comparison of novel quantitative semi-automatic measurements using cine MRI. Neurogastroenterology and Motility, 28(3), 327-335. https://doi.org/10.1111/nmo.12727

Background

Recently, cine magnetic resonance imaging (MRI) has shown promise for visualizing movement of the colonic wall, although assessment of data has been subjective and observer dependent. This study aimed to develop an objective and semi-au... Read More about Colon wall motility: comparison of novel quantitative semi-automatic measurements using cine MRI.

Imaging gray matter with concomitant null point imaging from the phase sensitive inversion recovery sequence (2015)
Journal Article
Mougin, O., Abdel-Fahim, R., Dineen, R., Pitiot, A., Evangelou, N., & Gowland, P. (2016). Imaging gray matter with concomitant null point imaging from the phase sensitive inversion recovery sequence. Magnetic Resonance in Medicine, 76(5), 1512-1516. https://doi.org/10.1002/mrm.26061

Purpose

To present an improved three-dimensional (3D) interleaved phase sensitive inversion recovery (PSIR) sequence including a concomitantly acquired new contrast, null point imaging (NPI), to help detect and classify abnormalities in cortical g... Read More about Imaging gray matter with concomitant null point imaging from the phase sensitive inversion recovery sequence.