Outputs (189)

Fast detection and structural identification of carbocations on zeolites by dynamic nuclear polarization enhanced solid-state NMR (2018)
Journal Article
Xiao, D., Xu, S., Brownbill, N. J., Paul, S., Chen, L.-H., Pawsey, S., Aussenac, F., Su, B.-L., Han, X., Bao, X., Liu, Z., & Blanc, F. (2018). Fast detection and structural identification of carbocations on zeolites by dynamic nuclear polarization enhanced solid-state NMR. Chemical Science, 9(43), 8184-8193. https://doi.org/10.1039/c8sc03848a

Acidic zeolites are porous aluminosilicates used in a wide range of industrial processes such as adsorption and catalysis. The formation of carbocation intermediates plays a key role in reactivity, selectivity and deactivation in heterogeneous cataly... Read More about Fast detection and structural identification of carbocations on zeolites by dynamic nuclear polarization enhanced solid-state NMR.

Altered nucleus basalis connectivity predicts treatment response in mild cognitive impairment (2018)
Journal Article
Meng, D., Li, X., Bauer, M., Taylor, J.-P., Auer, D. P., & Alzheimer's Disease Neuroimaging Initiative. (2018). Altered nucleus basalis connectivity predicts treatment response in mild cognitive impairment. Radiology, 289(3), 775-785. https://doi.org/10.1148/radiol.2018180092

Purpose: To determine whether functional connectivity (FC) mapping of nucleus basalis of Meynert (NBM) cholinergic network (hereafter, NBM FC) could provide a biomarker of central cholinergic deficits with predictive potential for response to choline... Read More about Altered nucleus basalis connectivity predicts treatment response in mild cognitive impairment.

Using MRI to study the alterations in liver blood flow, perfusion and oxygenation in response to physiological stress challenges: meal, hyperoxia and hypercapnia (2018)
Journal Article
Cox, E. F., Palaniyappan, N., Aithal, G. P., Guha, I. N., & Francis, S. T. (in press). Using MRI to study the alterations in liver blood flow, perfusion and oxygenation in response to physiological stress challenges: meal, hyperoxia and hypercapnia. Journal of Magnetic Resonance Imaging,

Background: Non-invasive assessment of dynamic changes in liver blood flow, perfusion and oxygenation using magnetic resonance imaging (MRI) may allow detection of subtle haemodynamic alterations in cirrhosis.
Purpose: To assess the feasibility of... Read More about Using MRI to study the alterations in liver blood flow, perfusion and oxygenation in response to physiological stress challenges: meal, hyperoxia and hypercapnia.

Early variations in white matter microstructure and depression outcome in adolescents with subthreshold-depression (2018)
Journal Article
Vulser, H., Martinot, M.-L. P., Artiges, E., Miranda, R., Pentilla, J., Grimmer, Y., van Noort, B. M., Stringaris, A., Struve, M., Fadai, T., Kappel, V., Goodman, R., Tzavara, E., Massaad, C., Banaschewski, T., Barker, G. J., Bokde, A. L., Bromberg, U., Brühl, R., Büchel, C., …Lemaitre, H. (2018). Early variations in white matter microstructure and depression outcome in adolescents with subthreshold-depression. American Journal of Psychiatry, 175(12), 1255-1264. https://doi.org/10.1176/appi.ajp.2018.17070825

Objective: White matter microstructure alterations have recently been associated with adolescence depressive episodes, but it is unknown whether they predate depression. We investigated whether subthreshold-depression in adolescence is associated wit... Read More about Early variations in white matter microstructure and depression outcome in adolescents with subthreshold-depression.

Demonstration of differences in colonic volumes, transit, chyme consistency and response to psyllium between healthy and constipated subjects using magnetic resonance imaging (2018)
Journal Article
Major, G., Murray, K., Singh, G., Nowak, A., Hoad, C. L., Marciani, L., Silos-Santiago, A., Kurtz, C. B., Johnston, J., Gowland, P., & Spiller, R. C. (2018). Demonstration of differences in colonic volumes, transit, chyme consistency and response to psyllium between healthy and constipated subjects using magnetic resonance imaging. Neurogastroenterology and Motility, 30(9), Article e13400. https://doi.org/10.1111/nmo.13400

Background: In functional gastrointestinal disorders a lack of objective biomarkers limits evaluation of underlying mechanisms. We aimed to demonstrate the utility of Magnetic Resonance Imaging (MRI) for this task using psyllium, an effective constip... Read More about Demonstration of differences in colonic volumes, transit, chyme consistency and response to psyllium between healthy and constipated subjects using magnetic resonance imaging.

Magnetic resonance imaging on sodium nuclei: potential medical applications of 23Na MRI (2018)
Journal Article
Sadykhov, E., Pirogov, Y., Anisimov, N., Gulyaev, M., Pavlovskaya, G., Meersmann, T., Belyaev, V., & Fomina, D. (2018). Magnetic resonance imaging on sodium nuclei: potential medical applications of 23Na MRI. Applied Magnetic Resonance, 925-957. https://doi.org/10.1007/s00723-018-1045-7

Sodium is a key element in a living organism. The increase of its concentration is an indicator of many pathological conditions. 23Na magnetic resonance imaging (MRI) is a quantitative method that allows to determine the sodium content in tissues and... Read More about Magnetic resonance imaging on sodium nuclei: potential medical applications of 23Na MRI.

A low FODMAP diet is associated with changes in the microbiota and reduction in breath hydrogen but not colonic volume in healthy subjects (2018)
Journal Article
Sloan, T. J., Jalanka, J., Major, G. A. D., Krishnasamy, S., Pritchard, S., Abdelrazig, S., Korpela, K., Singh, G., Mulvenna, C., Hoad, C. L., Marciani, L., Barrett, D. A., Lomer, M. C. E., de Vos, W. M., Gowland, P. A., & Spiller, R. C. (2018). A low FODMAP diet is associated with changes in the microbiota and reduction in breath hydrogen but not colonic volume in healthy subjects. PLoS ONE, 13(7), Article e0201410. https://doi.org/10.1371/journal.pone.0201410

Background & aims

Ingestion of poorly digested, fermentable carbohydrates (fermentable oligo-, di-, mono-saccharides and polyols; FODMAPs) have been implicated in exacerbating intestinal symptoms and the reduction of intake with symptom alleviatio... Read More about A low FODMAP diet is associated with changes in the microbiota and reduction in breath hydrogen but not colonic volume in healthy subjects.

Dynamic nuclear polarisation enhanced solid-state nuclear magnetic resonance studies of surface modification of γ-alumina (2018)
Journal Article
Mais, M., Paul, S., Barrow, N. S., & Titman, J. J. (2018). Dynamic nuclear polarisation enhanced solid-state nuclear magnetic resonance studies of surface modification of γ-alumina. Johnson Matthey Technology Review, 62(3), 271-278. https://doi.org/10.1595/205651318x696765

Dynamic nuclear polarization (DNP) gives large (>100-fold) signal enhancements in solid-state NMR spectra via the transfer of spin polarization from unpaired electrons from radicals implanted in the sample. This means that the detailed information ab... Read More about Dynamic nuclear polarisation enhanced solid-state nuclear magnetic resonance studies of surface modification of γ-alumina.

Multi organ assessment of compensated cirrhosis patients using quantitative magnetic resonance imaging (2018)
Journal Article
Bradley, C. R., Cox, E. F., Scott, R. A., James, M. W., Kaye, P., Aithal, G. P., Francis, S. T., & Guha, I. N. (2018). Multi organ assessment of compensated cirrhosis patients using quantitative magnetic resonance imaging. Journal of Hepatology, 69(5), 1015-1024. https://doi.org/10.1016/j.jhep.2018.05.037

Background and Aims: Advancing liver disease results in deleterious changes in a number of critical organs. The ability to measure structure, blood flow and tissue perfusion within multiple organs in a single scan has implications for determining the... Read More about Multi organ assessment of compensated cirrhosis patients using quantitative magnetic resonance imaging.

Parkinson's disease related signal change in the nigrosomes 1–5 and the substantia nigra using T2* weighted 7T MRI (2018)
Journal Article
Schwarz, S. T., Mougin, O., Xing, Y., Blazejewska, A., Bajaj, N., Auer, D. P., & Gowland, P. (2018). Parkinson's disease related signal change in the nigrosomes 1–5 and the substantia nigra using T2* weighted 7T MRI. NeuroImage: Clinical, 19, 683-689. https://doi.org/10.1016/j.nicl.2018.05.027

Improved markers for the progression of Parkinson's disease (PD) are required. Previous work has proven that iron dependent MRI scans can detect the largest Nigrosome (N1) within the substantia nigra (SN) pars compacta and changes in PD. Histopatholo... Read More about Parkinson's disease related signal change in the nigrosomes 1–5 and the substantia nigra using T2* weighted 7T MRI.