Outputs (53)

Serum Cytokine Alterations Associated with Age of Patients with Nephropathia Epidemica (2022)
Journal Article
Shakirova, V., Khaertynova, I., Markelova, M., Tarlinton, R., Behnke, J., Martynova, E., Garanina, E., Rizvanov, A., & Khaiboullina, S. (2022). Serum Cytokine Alterations Associated with Age of Patients with Nephropathia Epidemica. BioMed Research International, 2022, Article 4685288. https://doi.org/10.1155/2022/4685288

Nephropathia epidemica (NE) is a zoonotic disease caused by hantaviruses transmitted from rodents, endemic in the Republic of Tatarstan, Russia. The disease presents clinically with mild, moderate, and severe forms, and time-dependent febrile, oligur... Read More about Serum Cytokine Alterations Associated with Age of Patients with Nephropathia Epidemica.

Retroviral integrations contribute to elevated host cancer rates during germline invasion (2021)
Journal Article
McEwen, G. K., Alquezar-Planas, D. E., Dayaram, A., Gillett, A., Tarlinton, R., Mongan, N., Chappell, K. J., Henning, J., Tan, M., Timms, P., Young, P. R., Roca, A. L., & Greenwood, A. D. (2021). Retroviral integrations contribute to elevated host cancer rates during germline invasion. Nature Communications, 12(1), https://doi.org/10.1038/s41467-021-21612-7

© 2021, The Author(s). Repeated retroviral infections of vertebrate germlines have made endogenous retroviruses ubiquitous features of mammalian genomes. However, millions of years of evolution obscure many of the immediate repercussions of retrovira... Read More about Retroviral integrations contribute to elevated host cancer rates during germline invasion.

Role of Viruses in the Pathogenesis of Multiple Sclerosis (2020)
Journal Article
Tarlinton, R. E., Martynova, E., Rizvanov, A., Khaiboullina, S., & Verma, S. (2020). Role of Viruses in the Pathogenesis of Multiple Sclerosis. Viruses, 12(6), 643. https://doi.org/10.3390/v12060643

Multiple sclerosis (MS) is an immune inflammatory disease, where the underlying etiological cause remains elusive. Multiple triggering factors have been suggested, including environmental, genetic and gender components. However, underlying infectious... Read More about Role of Viruses in the Pathogenesis of Multiple Sclerosis.

Retrieval of the Complete Coding Sequence of the UK-Endemic Tatenale Orthohantavirus Reveals Extensive Strain Variation and Supports Its Classification as a Novel Species (2020)
Journal Article
Chappell, J. G., Tsoleridis, T., Onianwa, O., Drake, G., Ashpole, I., Dobbs, P., Edema, W., Kumi-Ansah, F., Bennett, M., Tarlinton, R. E., Ball, J. K., & McClure, C. P. (2020). Retrieval of the Complete Coding Sequence of the UK-Endemic Tatenale Orthohantavirus Reveals Extensive Strain Variation and Supports Its Classification as a Novel Species. Viruses, 12(4), Article 454. https://doi.org/10.3390/v12040454

©2020 by the authors. Licensee MDPI, Basel, Switzerland. Orthohantaviruses are globally distributed viruses, associated with rodents and other small mammals. However, data on the circulation of orthohantaviruses within the UK, particularly the UK-end... Read More about Retrieval of the Complete Coding Sequence of the UK-Endemic Tatenale Orthohantavirus Reveals Extensive Strain Variation and Supports Its Classification as a Novel Species.

Pathological Findings in Koala Retrovirus-positive Koalas (Phascolarctos cinereus) from Northern and Southern Australia (2020)
Journal Article
Fabijan, J., Sarker, N., Speight, N., Owen, H., Meers, J., Simmons, G., Seddon, J., Emes, R. D., Tarlinton, R., Hemmatzadeh, F., Woolford, L., & Trott, D. J. (2020). Pathological Findings in Koala Retrovirus-positive Koalas (Phascolarctos cinereus) from Northern and Southern Australia. Journal of Comparative Pathology, 176, 50-66. https://doi.org/10.1016/j.jcpa.2020.02.003

© 2020 Elsevier Ltd Koala retrovirus (KoRV) infection shows differences in prevalence and load between northern and southern Australian koala populations; however, the effect of this on diseases such as lymphoma and chlamydial disease is unclear. Thi... Read More about Pathological Findings in Koala Retrovirus-positive Koalas (Phascolarctos cinereus) from Northern and Southern Australia.

Differential expression of HERV-W in peripheral blood in multiple sclerosis and healthy patients in two different ethnic groups (2020)
Journal Article
Tarlinton, R., Wang, B., Morandi, E., Gran, B., Khaibullin, T., Martynova, E., Rizvanov, A., & Khaiboullina, S. (2020). Differential expression of HERV-W in peripheral blood in multiple sclerosis and healthy patients in two different ethnic groups. Frontiers in Pharmacology, 10, Article 1645. https://doi.org/10.3389/fphar.2019.01645

Copyright © 2020 Tarlinton, Wang, Morandi, Gran, Khaiboullin, Martynova, Rizvanov and Khaiboullina. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction... Read More about Differential expression of HERV-W in peripheral blood in multiple sclerosis and healthy patients in two different ethnic groups.

Novel insights into viral infection and oncogenesis from Koala Retrovirus (KoRV) infection of HEK293T cells (2020)
Journal Article
Sarker, N., Tarlinton, R., Owen, H., David Emes, R., Seddon, J., Simmons, G., & Meers, J. (2020). Novel insights into viral infection and oncogenesis from Koala Retrovirus (KoRV) infection of HEK293T cells. Gene, 733, Article 144366. https://doi.org/10.1016/j.gene.2020.144366

Koala retrovirus is thought to be an underlying cause of high levels of neoplasia and immunosuppression in koalas. While epidemiology studies suggest a strong link between KoRV and disease it has been difficult to prove causality because of the compl... Read More about Novel insights into viral infection and oncogenesis from Koala Retrovirus (KoRV) infection of HEK293T cells.

Koala retrovirus viral load and disease burden in distinct northern and southern koala populations (2020)
Journal Article
Sarker, N., Fabijan, J., Owen, H., Seddon, J., Simmons, G., Speight, N., Kaler, J., Woolford, L., Emes, R. D., Hemmatzadeh, F., Trott, D., Meers, J., & Tarlinton, R. E. (2020). Koala retrovirus viral load and disease burden in distinct northern and southern koala populations. Scientific Reports, 10(1), 263. https://doi.org/10.1038/s41598-019-56546-0

Koala retrovirus (KoRV) displays features of both an endogenous and exogenous virus and is linked to neoplasia and immunosuppression in koalas. This study explores the apparent differences in the nature and impact of KoRV infection between geographic... Read More about Koala retrovirus viral load and disease burden in distinct northern and southern koala populations.

Discovery and Prevalence of Divergent RNA Viruses in European Field Voles and Rabbits (2019)
Journal Article
Tsoleridis, T., Chappell, J. G., Monchatre-Leroy, E., Umhang, G., Shi, M., Bennett, M., Tarlinton, R. E., McClure, C. P., Holmes, E. C., & Ball, J. K. (2019). Discovery and Prevalence of Divergent RNA Viruses in European Field Voles and Rabbits. Viruses, 12(1), Article 47. https://doi.org/10.3390/v12010047

The advent of unbiased metagenomic virus discovery has revolutionized studies of virus biodiversity and evolution. Despite this, our knowledge of the virosphere, including in mammalian species, remains limited. We used unbiased metagenomic sequencing... Read More about Discovery and Prevalence of Divergent RNA Viruses in European Field Voles and Rabbits.

Genetic diversity of Koala retrovirus env gene subtypes: insights into northern and southern koala populations (2019)
Journal Article
Sarker, N., Fabijan, J., Seddon, J., Tarlinton, R., Owen, H., Simmons, G., Thia, J., Mark Blanchard, A., Speight, N., Kaler, J., Emes, R. D., Woolford, L., Trott, D., Hemmatzadeh, F., & Meers, J. (2019). Genetic diversity of Koala retrovirus env gene subtypes: insights into northern and southern koala populations. Journal of General Virology, 100(9), 1328-1339. https://doi.org/10.1099/jgv.0.001304

Koala retrovirus (KoRV) is a recently endogenised retrovirus associated with neoplasia and immunosuppression in koala populations. The virus is known to display sequence variability and to be present at varying prevalence in different populations, wi... Read More about Genetic diversity of Koala retrovirus env gene subtypes: insights into northern and southern koala populations.