Outputs (144)

A rapid IL-17 response to Cryptosporidium parvum in the bovine intestine (2017)
Journal Article
Drinkall, E., Wass, M. J., Coffey, T. J., & Flynn, R. J. (in press). A rapid IL-17 response to Cryptosporidium parvum in the bovine intestine. Veterinary Immunology and Immunopathology, 191, https://doi.org/10.1016/j.vetimm.2017.07.009

Cryptosporidium parvum causes diarrhoea, due to villi damage, in livestock and humans globally. Immunity develops after repeated infections but initial infections can be severe, highlighting the importance of early infection dynamics. We have modelle... Read More about A rapid IL-17 response to Cryptosporidium parvum in the bovine intestine.

Unique characterisation of Langerhans cells in the spleen of the African catfish (Clarias gariepinus) (2017)
Journal Article
Zaghloul, D. M., Derbalah, A., & Rutland, C. S. (2017). Unique characterisation of Langerhans cells in the spleen of the African catfish (Clarias gariepinus). https://doi.org/10.19185/matters.201703000005

The African catfish (Clarias gariepinus) has increasingly become an economically important food source especially in Africa, Asia and Europe, with exports extending to countries throughout the world. In the last 25 years, aquaculture of this species... Read More about Unique characterisation of Langerhans cells in the spleen of the African catfish (Clarias gariepinus).

Illustrated Dictionary of Parasitology in the Post-Genomic Era (2017)
Book
Elsheikha, H., & Jarroll, E. L. (2017). Illustrated Dictionary of Parasitology in the Post-Genomic Era. Caister Academic Press Limited. https://doi.org/10.21775/9781910190678

This illustrated dictionary provides concise definitions and explanations of parasitology terms and related molecular processes presented in an easy-to-use, A-Z order with particular emphasis on terms that are of relevance to parasite biotechnology a... Read More about Illustrated Dictionary of Parasitology in the Post-Genomic Era.

Profiling of the perturbed metabolomic state of mouse spleen during acute and chronic toxoplasmosis (2017)
Journal Article
Chen, X.-Q., Zhou, C.-X., Elsheikha, H. M., He, S., Hu, G.-X., & Zhu, X.-Q. (2017). Profiling of the perturbed metabolomic state of mouse spleen during acute and chronic toxoplasmosis. Parasites and Vectors, 10(1), Article 339. https://doi.org/10.1186/s13071-017-2282-6

Background

Toxoplasma gondii, a common opportunistic protozoan, is a leading cause of illness and mortality among immunosuppressed individuals and during congenital infections. Current therapeutic strategies for toxoplasmosis are not fully effecti... Read More about Profiling of the perturbed metabolomic state of mouse spleen during acute and chronic toxoplasmosis.

Factors affecting the cost-effectiveness of on-farm culture prior to the treatment of clinical mastitis in dairy cows (2017)
Journal Article
Down, P., Bradley, A. J., Breen, J., & Green, M. J. (2017). Factors affecting the cost-effectiveness of on-farm culture prior to the treatment of clinical mastitis in dairy cows. Preventive Veterinary Medicine, 145, https://doi.org/10.1016/j.prevetmed.2017.07.006

The objective of this study was to use probabilistic sensitivity analysis to evaluate the cost-effectiveness of using an on-farm culture (OFC) approach to the treatment of clinical mastitis in dairy cows and compare this to a ‘standard’ treatment app... Read More about Factors affecting the cost-effectiveness of on-farm culture prior to the treatment of clinical mastitis in dairy cows.

Toxoplasma gondii infection in farmed wild boars (Sus scrofa) in three cities of northeast China (2017)
Journal Article
Bai, M.-J., Zou, Y., Elsheikha, H. M., Ma, J.-G., Zheng, W.-B., Zhao, Q., …Zhu, X.-Q. (2017). Toxoplasma gondii infection in farmed wild boars (Sus scrofa) in three cities of northeast China. Foodborne Pathogens and Disease, 14(7), 379-385. https://doi.org/10.1089/fpd.2016.2260

The apicomplexan protozoan parasite Toxoplasma gondii is a widely distributed etiological agent of foodborne illness. This parasite can cause production losses in livestock and serious disease in humans through consumption of contaminated meat. Pig m... Read More about Toxoplasma gondii infection in farmed wild boars (Sus scrofa) in three cities of northeast China.

Multiple species comparison of cardiac troponin T and dystrophin: unravelling the DNA behind dilated cardiomyopathy (2017)
Journal Article
England, J., Loughna, S., & Rutland, C. S. (2017). Multiple species comparison of cardiac troponin T and dystrophin: unravelling the DNA behind dilated cardiomyopathy. Journal of Cardiovascular Development and Disease, 4(3), Article 8. https://doi.org/10.3390/jcdd4030008

Animals have frequently been used as models for human disorders and mutations. Following advances in genetic testing and treatment options, and the decreasing cost of these technologies in the clinic, mutations in both companion and commercial animal... Read More about Multiple species comparison of cardiac troponin T and dystrophin: unravelling the DNA behind dilated cardiomyopathy.

Comparative proteomic analysis of virulent and avirulent strains of Toxoplasma gondii reveals strain-specific patterns (2017)
Journal Article
Zhou, D.-H., Wang, Z.-X., Zhou, C.-X., He, S., Elsheikha, H. M., & Zhu, X.-Q. (2017). Comparative proteomic analysis of virulent and avirulent strains of Toxoplasma gondii reveals strain-specific patterns. Oncotarget, 8(46), https://doi.org/10.18632/oncotarget.19077

Research exploring the proteome of Toxoplasma gondii oocysts has gained momentum over the past few years. However, little is known about the oocyst’s protein repertoires that contribute to differential virulence among T. gondii strains. Here, we used... Read More about Comparative proteomic analysis of virulent and avirulent strains of Toxoplasma gondii reveals strain-specific patterns.

Seroepidemiology of Toxoplasma gondii infection in patients with liver disease in eastern China (2017)
Journal Article
Tian, A., Li, G., Elsheikha, H. M., Gardner, D., Zhang, X., Dong, W., …Zhu, X. (2017). Seroepidemiology of Toxoplasma gondii infection in patients with liver disease in eastern China. Epidemiology and Infection, 145(11), 2296-2302. https://doi.org/10.1017/S0950268817001327

The role of the protozoan parasite Toxoplasma gondii in the pathogenesis of liver disease has recently gained much interest. The aim of this study was to determine the prevalence and risk factors associated with T. gondii infection in patients with l... Read More about Seroepidemiology of Toxoplasma gondii infection in patients with liver disease in eastern China.

Meningeal carcinomatosis and spinal cord infiltration caused by a locally invasive pulmonary adenocarcinoma in a cat (2017)
Journal Article
Posporis, C., Grau-Roma, L., Travetti, O., Oliveira, M., Polledo, L., & Wessmann, A. (2017). Meningeal carcinomatosis and spinal cord infiltration caused by a locally invasive pulmonary adenocarcinoma in a cat. Journal of Feline Medicine and Surgery Open Reports, 3(2), https://doi.org/10.1177/2055116917742812

A 12-year-old domestic shorthair cat was presented with acute non-painful hindlimb proprioceptive ataxia localising to T3–L3 spinal cord segments. MRI revealed paravertebral muscular hyperintensity on T2-weighted images at the level of T7–T8 vertebra... Read More about Meningeal carcinomatosis and spinal cord infiltration caused by a locally invasive pulmonary adenocarcinoma in a cat.