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Outputs (1375)

Quantification of play behaviour in farmed calves using automated ultra-wide band location data and its association with age, weaning and health status (2024)
Journal Article
Vázquez-Diosdado, J., Doidge, C., Bushby, E., Occhiuto, F., & Kaler, J. (2024). Quantification of play behaviour in farmed calves using automated ultra-wide band location data and its association with age, weaning and health status. Scientific Reports, 14, Article 8872

Play behaviour can act as an indicator of positive animal welfare. Previous attempts to predict play behaviour in farmed calves are limited because of the classification methods used, which lead to overestimation, and the short time periods that calv... Read More about Quantification of play behaviour in farmed calves using automated ultra-wide band location data and its association with age, weaning and health status.

Identifying veterinary surgeons’ barriers to, and potential solutions for, improving antimicrobial stewardship among sheep farmers in Northern Ireland (2024)
Journal Article
Crawford, P. E., Hamer, K., Lovatt, F., Behnke, M. C., & Robinson, P. A. (2024). Identifying veterinary surgeons’ barriers to, and potential solutions for, improving antimicrobial stewardship among sheep farmers in Northern Ireland. Veterinary Record Open, 11(1), Article e278. https://doi.org/10.1002/vro2.78

Background: In order to improve antimicrobial stewardship (AMS), including changes in antimicrobial prescribing and use, an enhanced understanding is needed of the barriers that veterinary surgeons (vets) encounter to institute such change. Methods:... Read More about Identifying veterinary surgeons’ barriers to, and potential solutions for, improving antimicrobial stewardship among sheep farmers in Northern Ireland.

Trx4, a novel thioredoxin protein, is important for Toxoplasma gondii fitness (2024)
Journal Article
Zhang, Z., Wang, M., Sun, L., Elsheikha, H. M., Lei, C., Wang, J., …Li, T. (2024). Trx4, a novel thioredoxin protein, is important for Toxoplasma gondii fitness. Parasites and Vectors, 17(1), Article 178. https://doi.org/10.1186/s13071-024-06259-9

Background To successfully replicate within the host cell, Toxoplasma gondii employs several mechanisms to overcome the host cell defenses and mitigate the harmful effects of the free radicals resulting from its own metabolic processes using effector... Read More about Trx4, a novel thioredoxin protein, is important for Toxoplasma gondii fitness.

Genomic and Phenotypic Analysis of Salmonella enterica Bacteriophages Identifies Two Novel Phage Species (2024)
Journal Article
Bhandare, S., Lawal, O. U., Colavecchio, A., Cadieux, B., Zahirovich-Jovich, Y., Zhong, Z., …Goodridge, L. (2024). Genomic and Phenotypic Analysis of Salmonella enterica Bacteriophages Identifies Two Novel Phage Species. Microorganisms, 12(4), Article 695. https://doi.org/10.3390/microorganisms12040695

Bacteriophages (phages) are potential alternatives to chemical antimicrobials against pathogens of public health significance. Understanding the diversity and host specificity of phages is important for developing effective phage biocontrol approache... Read More about Genomic and Phenotypic Analysis of Salmonella enterica Bacteriophages Identifies Two Novel Phage Species.

A core genome multi-locus sequence typing scheme for Streptococcus uberis: an evolution in typing a genetically diverse pathogen (2024)
Journal Article
Whiley, D., Jolley, K., Blanchard, A., Coffey, T., & Leigh, J. (2024). A core genome multi-locus sequence typing scheme for Streptococcus uberis: an evolution in typing a genetically diverse pathogen. Microbial Genomics, 10(3), https://doi.org/10.1099/mgen.0.001225

Streptococcus uberis is a globally endemic and poorly controlled cause of bovine mastitis impacting the sustainability of the modern dairy industry. A core genome was derived from 579 newly sequenced S. uberis isolates, along with 305 publicly availa... Read More about A core genome multi-locus sequence typing scheme for Streptococcus uberis: an evolution in typing a genetically diverse pathogen.

Global prevalence and risk factors associated with Toxoplasma gondii infection in wild birds: A systematic review and meta-analysis (2024)
Journal Article
Chen, C., Qin, S., Yang, X., Li, X., Cai, Y., Lei, C., …Cao, H. (2024). Global prevalence and risk factors associated with Toxoplasma gondii infection in wild birds: A systematic review and meta-analysis. Preventive Veterinary Medicine, 226, Article 106187. https://doi.org/10.1016/j.prevetmed.2024.106187

A systematic review and meta-analysis were performed to identify the global prevalence and factors associated with Toxoplasma gondii infection in wild birds. Six bibliographic databases (Chinese National Knowledge Infrastructure, VIP Chinese Journal... Read More about Global prevalence and risk factors associated with Toxoplasma gondii infection in wild birds: A systematic review and meta-analysis.

Expression profiles of host miRNAs and circRNAs and ceRNA network during Toxoplasma gondii lytic cycle (2024)
Journal Article
Wang, S., Wang, X., He, J., Zheng, W., Zhu, X., Elsheikha, H. M., & Zhou, C. (2024). Expression profiles of host miRNAs and circRNAs and ceRNA network during Toxoplasma gondii lytic cycle. Parasitology Research, 123(2), Article 145. https://doi.org/10.1007/s00436-024-08152-x

Toxoplasma gondii is an opportunistic protozoan parasite that is highly prevalent in the human population and can lead to adverse health consequences in immunocompromised patients and pregnant women. Noncoding RNAs, such as microRNAs (miRNAs) and cir... Read More about Expression profiles of host miRNAs and circRNAs and ceRNA network during Toxoplasma gondii lytic cycle.

Dolphin-WET—Development of a Welfare Evaluation Tool for Bottlenose Dolphins (Tursiops truncatus) under Human Care (2024)
Journal Article
Baumgartner, K., Hüttner, T., Clegg, I. L. K., Garcia Hartmann, M., Garcia-Párraga, D., Manteca, X., …Delfour, F. (2024). Dolphin-WET—Development of a Welfare Evaluation Tool for Bottlenose Dolphins (Tursiops truncatus) under Human Care. Animals, 14(5), Article 701. https://doi.org/10.3390/ani14050701

Ensuring high standards of animal welfare is not only an ethical duty for zoos and aquariums, but it is also essential to achieve their conservation, education, and research goals. While for some species, animal welfare assessment frameworks are alre... Read More about Dolphin-WET—Development of a Welfare Evaluation Tool for Bottlenose Dolphins (Tursiops truncatus) under Human Care.

An in silico and in vitro assessment of the neurotoxicity of mefloquine (2024)
Journal Article
El Sharazly, B. M., Ahmed, A., Elsheikha, H. M., & Carter, W. G. (2024). An in silico and in vitro assessment of the neurotoxicity of mefloquine. Biomedicines, 12(3), Article 505. https://doi.org/10.3390/biomedicines12030505

Mefloquine (MQ) is a quinoline-based anti-malarial drug used for chemoprophylaxis or as treatment in combination with artesunate. Although MQ has clear anti-Plasmodium properties, it can induce neurotoxicity and undesired neuropsychiatric side effect... Read More about An in silico and in vitro assessment of the neurotoxicity of mefloquine.