Outputs (107)

Vasoactive intestinal peptide (VIP) differentially affects inflammatory immune responses in human monocytes infected with viable Salmonella or stimulated with LPS (2015)
Journal Article
Askar, B. A., Ibrahim, H., Barrow, P., & Foster, N. (2015). Vasoactive intestinal peptide (VIP) differentially affects inflammatory immune responses in human monocytes infected with viable Salmonella or stimulated with LPS. Peptides, 71, https://doi.org/10.1016/j.peptides.2015.06.009

We compared the effect of VIP on human blood monocytes infected with Salmonella typhimurium 4/74 or stimulated with LPS. VIP (10−7 M) increased monocyte viability by 24% and 9% when cultured for 24 h with 4/74 or Salmonella LPS (100 ng/ml), respectiv... Read More about Vasoactive intestinal peptide (VIP) differentially affects inflammatory immune responses in human monocytes infected with viable Salmonella or stimulated with LPS.

Development of a DNA-based microarray for the detection of zoonotic pathogens in rodent species (2015)
Journal Article
Giles, T., Yon, L., Hannant, D., Barrow, P., & Abu-Median, A.-B. (2015). Development of a DNA-based microarray for the detection of zoonotic pathogens in rodent species. Molecular and Cellular Probes, 29(6), https://doi.org/10.1016/j.mcp.2015.07.005

The demand for diagnostic tools that allow simultaneous screening of samples for multiple pathogens is increasing because they overcome the limitations of other methods, which can only screen for a single or a few pathogens at a time. Microarrays off... Read More about Development of a DNA-based microarray for the detection of zoonotic pathogens in rodent species.

Evidence for a novel Kit adhesion domain mediating human mast cell adhesion to structural airway cells (2015)
Journal Article
Gough, K. C., Maddison, B. C., Shikotra, A., Moiseeva, E. P., Yang, W., Jarvis, S., & Bradding, P. (2015). Evidence for a novel Kit adhesion domain mediating human mast cell adhesion to structural airway cells. Respiratory Research, 16, Article 86. https://doi.org/10.1186/s12931-015-0245-z

Background: Human lung mast cells (HLMCs) infiltrate the airway epithelium and airway smooth muscle (ASM) in asthmatic airways. The mechanism of HLMC adhesion to both cell types is only partly defined, and adhesion is not inhibited by function-blocki... Read More about Evidence for a novel Kit adhesion domain mediating human mast cell adhesion to structural airway cells.

HABIT: Horse Automated Behaviour Identification Tool: a position paper (2015)
Presentation / Conference Contribution
North, S., Hall, C., Roshier, A., & Mancini, C. HABIT: Horse Automated Behaviour Identification Tool: a position paper. Presented at ACI@BHCI (Animal Computer Interaction Workshop), British HCI 2015

HABIT (Horse Automated Behaviour Identification Tool) is an Animal Computer Interaction (ACI) project, on the interdisciplinary boundary between equitation science and computer science. HABIT will automate the analysis and recognition of horse-to-hor... Read More about HABIT: Horse Automated Behaviour Identification Tool: a position paper.

An investigation of the dynamics of intramammary infections acquired during the dry period on European dairy farms (2015)
Journal Article
Bradley, A. J., De Vliegher, S., Green, M. J., Larrosa, P., Payne, B., van de Leemput, E. S., Samson, O., Valckenier, D., Van Werven, T., Waldeck, H., White, V., & Goby, L. (2015). An investigation of the dynamics of intramammary infections acquired during the dry period on European dairy farms. Journal of Dairy Science, 98(9), https://doi.org/10.3168/jds.2014-8749

The dry period is acknowledged as playing a key role in mastitis epidemiology and yet surprisingly few studies have explored dry period infection dynamics in detail. The aim of this study was to investigate the dynamics of intramammary infection acro... Read More about An investigation of the dynamics of intramammary infections acquired during the dry period on European dairy farms.

The effect of Lameness before and during the breeding season on fertility in 10 pasture-based Irish dairy herds (2015)
Journal Article
Somers, J. R., Huxley, J., Lorenz, I., Doherty, M. L., & O'Grady, L. (2015). The effect of Lameness before and during the breeding season on fertility in 10 pasture-based Irish dairy herds. Irish Veterinary Journal, 68, Article 14. https://doi.org/10.1186/s13620-015-0043-4

Background: The effects of lameness on fertility have been documented frequently but few data are available from seasonally breeding, pasture-based herds (such as those used in Ireland) where cows are housed during the winter months but managed at pa... Read More about The effect of Lameness before and during the breeding season on fertility in 10 pasture-based Irish dairy herds.

Genetics of human and canine dilated cardiomyopathy (2015)
Journal Article
Simpson, S., Edwards, J., Ferguson-Mignan, T. F., Cobb, M., Mongan, N. P., & Rutland, C. S. (2015). Genetics of human and canine dilated cardiomyopathy. International Journal of Genomics, 2015, Article 204823. https://doi.org/10.1155/2015/204823

Cardiovascular disease is a leading cause of death in both humans and dogs. Dilated cardiomyopathy (DCM) accounts for a large number of these cases, reported to be the third most common form of cardiac disease in humans and the second most common in... Read More about Genetics of human and canine dilated cardiomyopathy.

Applications and limitations of measuring environmental DNA as indicators of the presence of aquatic animals (2015)
Journal Article
Rees, H. C., Gough, K. C., Middleditch, D. J., Patmore, J. R., & Maddison, B. C. (2015). Applications and limitations of measuring environmental DNA as indicators of the presence of aquatic animals. Journal of Applied Ecology, 52(4), https://doi.org/10.1111/1365-2664.12467

1. In Rees et al. (2014b), we reviewed the current status of environmental DNA (eDN A) tomonitor aquatic populations. Our aim was to focus on discus sion of methodologies used,application of eDNA analysis as a survey tool in ecology, and to include s... Read More about Applications and limitations of measuring environmental DNA as indicators of the presence of aquatic animals.

Use of stochastic simulation to evaluate the reduction in methane emissions and improvement in reproductive efficiency from routine hormonal interventions in dairy herds (2015)
Journal Article
Archer, S. C., Hudson, C., & Green, M. J. (2015). Use of stochastic simulation to evaluate the reduction in methane emissions and improvement in reproductive efficiency from routine hormonal interventions in dairy herds. PLoS ONE, 10(6), Article e0127846. https://doi.org/10.1371/journal.pone.0127846

This study predicts the magnitude and between herd variation in changes of methane emissions and production efficiency associated with interventions to improve reproductive efficiency in dairy cows. Data for 10,000 herds of 200 cows were simulated. P... Read More about Use of stochastic simulation to evaluate the reduction in methane emissions and improvement in reproductive efficiency from routine hormonal interventions in dairy herds.

Neuroblastoma arginase activity creates an immunosuppressive microenvironment that impairs autologous and engineered immunity (2015)
Journal Article
Mussai, F., Egan, S. A., Hunter, S., Webber, H., Fisher, J., Wheat, R., McConville, C., Sbirkov, Y., Wheeler, K., Bendle, G., Petrie, K., Anderson, J., Chesler, L., & De Santo, C. (2015). Neuroblastoma arginase activity creates an immunosuppressive microenvironment that impairs autologous and engineered immunity. Cancer Research, 75(15), https://doi.org/10.1158/0008-5472.CAN-14-3443

Neuroblastoma is the most common extra cranial solid tumour of childhood, and survival remains poor for patients with advanced disease. Novel immune therapies are currently in development, but clinical outcomes have not matched preclinical results. H... Read More about Neuroblastoma arginase activity creates an immunosuppressive microenvironment that impairs autologous and engineered immunity.