Outputs (117)

1001 MCQs for Parasitology Trainees: The Essential Revision Guide (2021)
Book
Elsheikha, H. (2021). 1001 MCQs for Parasitology Trainees: The Essential Revision Guide. Para Publishing Limited

With a broad range of 1001 multiple choice questions and answers, this book is the ideal resource for all parasitology trainees who need to revise and prepare for parasitology examinations. The questions are representative of curricula of veterinary... Read More about 1001 MCQs for Parasitology Trainees: The Essential Revision Guide.

Dysregulation of hepatic microRNA expression in C57BL/6 mice affected by excretory-secretory products of Fasciola gigantica (2020)
Journal Article
Shi, W., He, J.-J., Mei, X.-F., Lu, K.-J., Zeng, Z.-X., Zhang, Y.-Y., …Zhu, X.-Q. (2020). Dysregulation of hepatic microRNA expression in C57BL/6 mice affected by excretory-secretory products of Fasciola gigantica. PLoS Neglected Tropical Diseases, 14(12), Article e0008951. https://doi.org/10.1371/journal.pntd.0008951

The excretory-secretory products released by the liver fluke Fasciola gigantica (FgESPs) play important roles in regulating the host immune response during the infection. Identification of hepatic miRNAs altered by FgESPs may improve our understandin... Read More about Dysregulation of hepatic microRNA expression in C57BL/6 mice affected by excretory-secretory products of Fasciola gigantica.

ROP18-Mediated Transcriptional Reprogramming of HEK293T Cell Reveals New Roles of ROP18 in the Interplay Between Toxoplasma gondii and the Host Cell (2020)
Journal Article
Li, J., He, J., Elsheikha, H. M., Ma, J., Xu, X., & Zhu, X. (2020). ROP18-Mediated Transcriptional Reprogramming of HEK293T Cell Reveals New Roles of ROP18 in the Interplay Between Toxoplasma gondii and the Host Cell. Frontiers in Cellular and Infection Microbiology, 10, Article 586946. https://doi.org/10.3389/fcimb.2020.586946

Toxoplasma gondii secretes a number of virulence-related effector proteins, such as the rhoptry protein 18 (ROP18). To further broaden our understanding of the molecular functions of ROP18, we examined the transcriptional response of human embryonic... Read More about ROP18-Mediated Transcriptional Reprogramming of HEK293T Cell Reveals New Roles of ROP18 in the Interplay Between Toxoplasma gondii and the Host Cell.

Molecular prevalence, risk factors and genotypes of Toxoplasma gondii DNA in wild marine snails collected from offshore waters in eastern China (2020)
Journal Article
Cong, W., Elsheikha, H. M., Li, M., Ma, J., Zou, Y., & Jiang, Z. (2021). Molecular prevalence, risk factors and genotypes of Toxoplasma gondii DNA in wild marine snails collected from offshore waters in eastern China. Acta Tropica, 214, Article 105779. https://doi.org/10.1016/j.actatropica.2020.105779

Increasing evidence exisits for the role that shellfish play in the epidemiology of Toxoplasma gondii in marine environment. However, limited information is available on the level of T. gondii infection in wild marine snails, which can play a role in... Read More about Molecular prevalence, risk factors and genotypes of Toxoplasma gondii DNA in wild marine snails collected from offshore waters in eastern China.

Epidemiology, pathophysiology, diagnosis, and management of cerebral toxoplasmosis (2020)
Journal Article
Elsheikha, H. M., Marra, C. M., & Zhu, X.-Q. (2020). Epidemiology, pathophysiology, diagnosis, and management of cerebral toxoplasmosis. Clinical Microbiology Reviews, 34(1), https://doi.org/10.1128/CMR.00115-19

Toxoplasma gondii is known to infect a considerable number of mammalian and avian species and a substantial proportion of the world’s human population. The parasite has an impressive ability to disseminate within the host’s body and employs various t... Read More about Epidemiology, pathophysiology, diagnosis, and management of cerebral toxoplasmosis.

Proteomic profiling of the liver, hepatic lymph nodes, and spleen of buffaloes infected with fasciola gigantica (2020)
Journal Article
Hu, R.-S., Zhang, F.-K., Elsheikha, H. M., Ma, Q.-N., Ehsan, M., Zhao, Q., & Zhu, X.-Q. (2020). Proteomic profiling of the liver, hepatic lymph nodes, and spleen of buffaloes infected with fasciola gigantica. Pathogens, 9(12), Article 982. https://doi.org/10.3390/pathogens9120982

In the present study, we used an isobaric tag for relative and absolute quantitation (iTRAQ) proteomics technology to characterize the differentially expressed proteins (DEPs) in the liver, hepatic lymph nodes (hLNs), and spleen of buffaloes infected... Read More about Proteomic profiling of the liver, hepatic lymph nodes, and spleen of buffaloes infected with fasciola gigantica.

Toxocara canis Differentially Affects Hepatic MicroRNA Expression in Beagle Dogs at Different Stages of Infection (2020)
Journal Article
Zou, Y., Zheng, W., He, J., Elsheikha, H. M., Zhu, X., & Lu, Y. (2020). Toxocara canis Differentially Affects Hepatic MicroRNA Expression in Beagle Dogs at Different Stages of Infection. Frontiers in Veterinary Science, 7, https://doi.org/10.3389/fvets.2020.587273

Toxocara canis is a neglected zoonotic parasite, which threatens the health of dogs and humans worldwide. The molecular mechanisms that underlie the progression of T. canis infection remain mostly unknown. MicroRNAs (miRNAs) are small non-coding RNAs... Read More about Toxocara canis Differentially Affects Hepatic MicroRNA Expression in Beagle Dogs at Different Stages of Infection.

Picosecond ultrasonics for elasticity-based imaging and characterization of biological cells (2020)
Journal Article
Pérez-Cota, F., Fuentes-Domínguez, R., La Cavera III, S., Hardiman, W., Yao, M., Setchfield, K., …Clark, M. (2020). Picosecond ultrasonics for elasticity-based imaging and characterization of biological cells. Journal of Applied Physics, 128(16), Article 160902. https://doi.org/10.1063/5.0023744

© 2020 Author(s). Characterization of the elasticity of biological cells is growing as a new way to gain insight into cell biology. Cell mechanics are related to most aspects of cellular behavior, and applications in research and medicine are broad.... Read More about Picosecond ultrasonics for elasticity-based imaging and characterization of biological cells.

Transcriptomic Profiling of Mouse Brain During Acute and Chronic Infections by Toxoplasma gondii Oocysts (2020)
Journal Article
Hu, R., He, J., Elsheikha, H. M., Zou, Y., Ehsan, M., Ma, Q., …Cong, W. (2020). Transcriptomic Profiling of Mouse Brain During Acute and Chronic Infections by Toxoplasma gondii Oocysts. Frontiers in Microbiology, 11, Article 570903. https://doi.org/10.3389/fmicb.2020.570903

Infection by the protozoan Toxoplasma gondii can have a devastating impact on the structure and function of the brain of the infected individuals, particularly immunocompromised patients. A systems biology view of the brain transcriptome can identify... Read More about Transcriptomic Profiling of Mouse Brain During Acute and Chronic Infections by Toxoplasma gondii Oocysts.

Global profiling of lysine 2-hydroxyisobutyrylome in Toxoplasma gondii using affinity purification mass spectrometry (2020)
Journal Article
Nie, L.-B., Liang, Q.-L., Elsheikha, H. M., Du, R., Zhu, X.-Q., & Li, F.-C. (2020). Global profiling of lysine 2-hydroxyisobutyrylome in Toxoplasma gondii using affinity purification mass spectrometry. Parasitology Research, 119(12), 4061-4071. https://doi.org/10.1007/s00436-020-06923-w

Lysine 2-hydroxyisobutyrylation (Khib) is a recently discovered and evolutionarily conserved form of protein post-translational modification (PTM) found in mammalian and yeast cells. Previous studies have shown that Khib plays roles in the activity o... Read More about Global profiling of lysine 2-hydroxyisobutyrylome in Toxoplasma gondii using affinity purification mass spectrometry.