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Outputs (117)

Camellia sinensis solvent extract, epigallocatechin gallate and caffeine confer trophocidal and cysticidal effects against Acanthamoeba castellanii (2022)
Journal Article
Fakae, L. B., Harun, M. S., Ting, D. S. J., Dua, H. S., Cave, G. W., Zhu, X. Q., …Elsheikha, H. M. (2023). Camellia sinensis solvent extract, epigallocatechin gallate and caffeine confer trophocidal and cysticidal effects against Acanthamoeba castellanii. Acta Tropica, 237, Article 106729. https://doi.org/10.1016/j.actatropica.2022.106729

We examined the anti-acanthamoebic efficacy of green tea Camellia sinensis solvent extract (SE) or its chemical constituents against Acanthamoeba castellanii by using anti-trophozoite, anti-encystation, and anti-excystation assays. C. sinensis SE (62... Read More about Camellia sinensis solvent extract, epigallocatechin gallate and caffeine confer trophocidal and cysticidal effects against Acanthamoeba castellanii.

Microfluidic-Based Formulation of Essential Oils-Loaded Chitosan Coated PLGA Particles Enhances Their Bioavailability and Nematocidal Activity (2022)
Journal Article
Helal, M. A., Abdel-Gawad, A. M., Kandil, O. M., Khalifa, M. M., Morrison, A. A., Bartley, D. J., …Elsheikha, H. M. (2022). Microfluidic-Based Formulation of Essential Oils-Loaded Chitosan Coated PLGA Particles Enhances Their Bioavailability and Nematocidal Activity. Pharmaceutics, 14(10), Article 2030. https://doi.org/10.3390/pharmaceutics14102030

In this study, poly (lactic-co-glycolic) acid (PLGA) particles were synthesized and coated with chitosan. Three essential oil (EO) components (eugenol, linalool, and geraniol) were entrapped inside these PLGA particles by using the continuous flow-fo... Read More about Microfluidic-Based Formulation of Essential Oils-Loaded Chitosan Coated PLGA Particles Enhances Their Bioavailability and Nematocidal Activity.

Lipidomic changes in the liver of beagle dogs associated with Toxocara canis infection (2022)
Journal Article
Li, H. Y., Zou, Y., Elsheikha, H. M., Xu, Y., Cai, L., Xie, S. C., …Zheng, W. B. (2022). Lipidomic changes in the liver of beagle dogs associated with Toxocara canis infection. Frontiers in Cellular and Infection Microbiology, 12, Article 890589. https://doi.org/10.3389/fcimb.2022.890589

A global lipidomic analysis using liquid chromatography–tandem mass spectrometry was performed on the liver of beagle dogs infected with Toxocara canis to profile hepatic lipid species at 12h post-infection (hpi), 24 hpi, and 36 days post-infection (... Read More about Lipidomic changes in the liver of beagle dogs associated with Toxocara canis infection.

Terrestrial runoff influences the transport and contamination levels of Toxoplasma gondii in marine organisms (2022)
Journal Article
Li, M. Y., Kang, Y. H., Sun, W. C., Hao, Z. P., Elsheikha, H. M., & Cong, W. (2022). Terrestrial runoff influences the transport and contamination levels of Toxoplasma gondii in marine organisms. Science of the Total Environment, 851, Article 158168. https://doi.org/10.1016/j.scitotenv.2022.158168

There is a growing concern regarding the potential adverse impact of Toxoplasma gondii contamination of the marine environment on marine wildlife and public health. Terrestrial runoff is a significant route for dissemination of T. gondii oocysts from... Read More about Terrestrial runoff influences the transport and contamination levels of Toxoplasma gondii in marine organisms.

Perception of UK companion animal veterinarians on risk assessment based parasite control (2022)
Journal Article
Bagster, A., & Elsheikha, H. (2022). Perception of UK companion animal veterinarians on risk assessment based parasite control. Veterinary parasitology (Amsterdam), 34, Article 100774. https://doi.org/10.1016/j.vprsr.2022.100774

Parasites can pose a risk to companion animals and potentially their owners. Current parasiticide use is possibly impacting the environment, increasing adverse reaction and resistance risk. As such parasiticides should be dispensed by the veterinary... Read More about Perception of UK companion animal veterinarians on risk assessment based parasite control.

RNA sequencing reveals dynamic expression of spleen lncRNAs and mRNAs in Beagle dogs infected by Toxocara canis (2022)
Journal Article
Xu, Y., Zheng, W. B., Li, H. Y., Cai, L., Zou, Y., Xie, S. C., …Elsheikha, H. M. (2022). RNA sequencing reveals dynamic expression of spleen lncRNAs and mRNAs in Beagle dogs infected by Toxocara canis. Parasites and Vectors, 15(1), Article 279. https://doi.org/10.1186/s13071-022-05380-x

Background: Toxocara canis is a cosmopolitan parasite with a significant adverse impact on the health of humans and animals. The spleen is a major immune organ that plays essential roles in protecting the host against various infections. However, its... Read More about RNA sequencing reveals dynamic expression of spleen lncRNAs and mRNAs in Beagle dogs infected by Toxocara canis.

555 Questions In Zoonotic and Vector-Borne Parasitic Diseases (2022)
Book
Elsheikha, H. (2022). 555 Questions In Zoonotic and Vector-Borne Parasitic Diseases. (Kindle Edition). Nottingham, England: Para Publishing Limited

This book is a comprehensive revision aid that will help parasitology students and trainees prepare for pre-test assessment and review. Readers can identify their own abilities and areas for development by completing 555 questions relevant to topics... Read More about 555 Questions In Zoonotic and Vector-Borne Parasitic Diseases.

Diagnosis and Management of Acanthamoeba Keratitis: A Continental Approach (2022)
Journal Article
Bouten, M., & Elsheikha, H. M. (2022). Diagnosis and Management of Acanthamoeba Keratitis: A Continental Approach. Parasitologia, 2(3), 167-197. https://doi.org/10.3390/parasitologia2030016

Acanthamoeba keratitis (AK) is a potentially blinding infection caused by protozoa found worldwide. The topical application of biguanides and diamidines is the most common anti-amoebic treatment for AK. In this study, we hypothesized that geographica... Read More about Diagnosis and Management of Acanthamoeba Keratitis: A Continental Approach.

Human pediculosis, a global public health problem (2022)
Journal Article
Fu, Y., Yao, C., Deng, Y., Elsheikha, H. M., Shao, R., Zhu, X., & Liu, G. (2022). Human pediculosis, a global public health problem. Infectious Diseases of Poverty, 11(1), Article 58. https://doi.org/10.1186/s40249-022-00986-w

Background: Human pediculosis is caused by hematophagous lice, which are transmitted between individuals via direct and/or indirect contact. Despite the public health importance of louse infestation, information concerning the global burden of pedicu... Read More about Human pediculosis, a global public health problem.

Global profiling of protein lysine malonylation in Toxoplasma gondii strains of different virulence and genetic backgrounds (2022)
Journal Article
Nie, L.-B., Liang, Q.-L., Wang, M., Du, R., Zhang, M.-Y., Elsheikha, H. M., & Zhu, X.-Q. (2022). Global profiling of protein lysine malonylation in Toxoplasma gondii strains of different virulence and genetic backgrounds. PLoS Neglected Tropical Diseases, 16(5), Article e0010431. https://doi.org/10.1371/journal.pntd.0010431

Lysine malonylation is a post-translational modification (PTM), which regulates many cellular processes. Limited information is available about the level of lysine malonylation variations between Toxoplasma gondii strains of distinct genetic lineages... Read More about Global profiling of protein lysine malonylation in Toxoplasma gondii strains of different virulence and genetic backgrounds.