Outputs (824)

Multimodal virtual environments: an opportunity to improve fire safety training? (2020)
Journal Article
Lawson, G., Roper, T., Shaw, E., Hsieh, M.-K., & Cobb, S. V. (2020). Multimodal virtual environments: an opportunity to improve fire safety training?. Policy and Practice in Health and Safety, 18(2), 155-168. https://doi.org/10.1080/14773996.2020.1796085

Fires and fire-related fatalities remain a tragic and frequent occurrence. Evidence has shown that humans adopt sub-optimal behaviours during fire incidents and, therefore, training is one possible means to improve occupant survival rates. We present... Read More about Multimodal virtual environments: an opportunity to improve fire safety training?.

Association between socioeconomic factors and soft drink consumption among adults in Cambodia: a cross-sectional study (2020)
Journal Article
Sim, S., Pisey, V., & Dewey, R. S. (2020). Association between socioeconomic factors and soft drink consumption among adults in Cambodia: a cross-sectional study. F1000Research, 9, Article 708. https://doi.org/10.12688/f1000research.24890.1

Background: Soft drinks are an attractive and popular drink, consumed by many people to fulfill their energy. However, soft drink consumption is an important risk factor for non-communicable diseases. This study aimed to investigate the association b... Read More about Association between socioeconomic factors and soft drink consumption among adults in Cambodia: a cross-sectional study.

Results of a UK-wide vignette study with occupational therapists to explore cognitive screening post-stroke (2020)
Journal Article
Geraghty, J., Ablewhite, J., das Nair, R., Lincoln, N., Kontou, E., Roffe, J., …Drummond, A. (2020). Results of a UK-wide vignette study with occupational therapists to explore cognitive screening post-stroke. International Journal of Therapy and Rehabilitation, 27(7),

Background.
There is a paucity of evidence in the UK regarding occupational therapy (OT) cognitive screening, and whether, and how, cognitive impairments are identified and assessed.

Aims
To identify current OT practice for the assessment of c... Read More about Results of a UK-wide vignette study with occupational therapists to explore cognitive screening post-stroke.

Untargeted metabolomics for uncovering biological markers of human skeletal muscle ageing (2020)
Journal Article
Wilkinson, D. J., Rodriguez-Blanco, G., Dunn, W. B., Phillips, B. E., Williams, J. P., Greenhaff, P. L., …Atherton, P. J. (2020). Untargeted metabolomics for uncovering biological markers of human skeletal muscle ageing. Aging, 12(13), 12517-12533. https://doi.org/10.18632/aging.103513

Ageing compromises skeletal muscle mass and function through poorly defined molecular aetiology. Here we have used untargeted metabolomics using UHPLC-MS to profile muscle tissue from young (n=10, 25±4y), middle aged (n=18, 50±4y) and older (n=18, 70... Read More about Untargeted metabolomics for uncovering biological markers of human skeletal muscle ageing.

Supervised Bayesian statistical learning to identify prognostic risk factor patterns from population data (2020)
Book Chapter
Crooks, C. J. (2020). Supervised Bayesian statistical learning to identify prognostic risk factor patterns from population data. In L. B. Pape-Haugaard, C. Lovis, I. Cort Madsen, P. Weber, P. Hostrup Nielsen, & P. Scott (Eds.), Digital personalized health and medicine: Proceedings of MIE 2020 (422-426). IOS Press. https://doi.org/10.3233/SHTI200195

Current methods for building risk models assume averaged uniform effects across populations. They use weighted sums of individual risk factors from regression models with only a few interactions, such as age. This does not allow risk factor effects t... Read More about Supervised Bayesian statistical learning to identify prognostic risk factor patterns from population data.

Entraining Movement-Related Brain Oscillations to Suppress Tics in Tourette Syndrome (2020)
Journal Article
Morera Maiquez, B., Sigurdsson, H. P., Dyke, K., Clarke, E., McGrath, P., Pasche, M., …Jackson, S. R. (2020). Entraining Movement-Related Brain Oscillations to Suppress Tics in Tourette Syndrome. Current Biology, 30(12), 2334-2342.e3. https://doi.org/10.1016/j.cub.2020.04.044

Tourette syndrome (TS) is a neuropsychiatric disorder characterised by the occurrence of vocal and motor tics. Tics are involuntary, repetitive, movements and vocalisations that occur in bouts, typically many times in a single day, and are often prec... Read More about Entraining Movement-Related Brain Oscillations to Suppress Tics in Tourette Syndrome.

Reducing dropout in acceptance and commitment therapy, mindfulness‐based cognitive therapy, and problem‐solving therapy for chronic pain and cancer patients using motivational interviewing (2020)
Journal Article
Malins, S., Biswas, S., Rathbone, J., Vogt, W., Pye, N., Levene, J., …Russell, J. (2020). Reducing dropout in acceptance and commitment therapy, mindfulness‐based cognitive therapy, and problem‐solving therapy for chronic pain and cancer patients using motivational interviewing. British Journal of Clinical Psychology, 59(3), 424-438. https://doi.org/10.1111/bjc.12254

Objective. Acceptance and Commitment Therapy, Mindfulness-Based Cognitive Therapy and Problem-Solving Therapy are types of Cognitive Behavioural Therapy (CBT) group that improve physical and mental health in chronic pain or cancer. However, dropout i... Read More about Reducing dropout in acceptance and commitment therapy, mindfulness‐based cognitive therapy, and problem‐solving therapy for chronic pain and cancer patients using motivational interviewing.

Gestational poly(I:C) attenuates, not exacerbates, the behavioral, cytokine and mTOR changes caused by isolation rearing in a rat ‘dual-hit’ model for neurodevelopmental disorders (2020)
Journal Article
Goh, J. Y., O'Sullivan, S. E., Shortall, S. E., Zordan, N., Piccinini, A. M., Potter, H. G., …King, M. V. (2020). Gestational poly(I:C) attenuates, not exacerbates, the behavioral, cytokine and mTOR changes caused by isolation rearing in a rat ‘dual-hit’ model for neurodevelopmental disorders. Brain, Behavior, and Immunity, 89, 100-117. https://doi.org/10.1016/j.bbi.2020.05.076

© 2020 Elsevier Inc. Many psychiatric illnesses have a multifactorial etiology involving genetic and environmental risk factors that trigger persistent neurodevelopmental impairments. Several risk factors have been individually replicated in rodents,... Read More about Gestational poly(I:C) attenuates, not exacerbates, the behavioral, cytokine and mTOR changes caused by isolation rearing in a rat ‘dual-hit’ model for neurodevelopmental disorders.

Elevated MMP9 expression in breast cancer is a predictor of shorter patient survival (2020)
Journal Article
Joseph, C., Alsaleem, M., Orah, N., Narasimha, P. L., Miligy, I. M., Kurozumi, S., …Rakha, E. A. (2020). Elevated MMP9 expression in breast cancer is a predictor of shorter patient survival. Breast Cancer Research and Treatment, 182, 267–282. https://doi.org/10.1007/s10549-020-05670-x

Purpose: MMP9 is a matricellular protein associated with extracellular matrix (ECM) remodelling, that promotes tumour progression, and modulates the activity of cell adhesion molecules and cytokines. This study aims to assess the prognostic value of... Read More about Elevated MMP9 expression in breast cancer is a predictor of shorter patient survival.

Exploration of temperature and shelf-life dependency of the therapeutically available Insulin Detemir (2020)
Journal Article
Beji, O., Gillis, R. B., Dinu, V., Jiwani, S. I., Gyasi-Antwi, P., Fisk, I. D., …Adams, G. G. (2020). Exploration of temperature and shelf-life dependency of the therapeutically available Insulin Detemir. European Journal of Pharmaceutics and Biopharmaceutics, 152, 340-347. https://doi.org/10.1016/j.ejpb.2020.05.016

© 2020 Elsevier B.V. Purpose: Insulin, in typical use, undergoes multiple changes in temperature; from refrigerator, to room temperature, to body temperature. Although long-term storage temperature has been well-studied, the short term changes to ins... Read More about Exploration of temperature and shelf-life dependency of the therapeutically available Insulin Detemir.