Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women

Steinthorsdottir, Valgerdur; McGinnis, Ralph; Williams, Nicholas O.; Stefansdottir, Lilja; Thorleifsson, Gudmar; Shooter, Scott; Fadista, Jo�o; Sigurdsson, Jon K.; Auro, Kirsi M.; Berezina, Galina; Borges, MariaCarolina; Bumpstead, Suzannah; Bybjerg-Grauholm, Jonas; Colgiu, Irina; Dolby, Vivien A.; Dudbridge, Frank; Engel, Stephanie M.; Franklin, Christopher S.; Frigge, Michael L.; Frisbaek, Yr; Geirsson, Reynir T.; Geller, Frank; Gretarsdottir, Solveig; Gudbjartsson, Daniel F.; Harmon, Quaker; Hougaard, David Michael; Hegay, Tatyana; Helgadottir, Anna; Hjartardottir, Sigrun; J��skel�inen, Tiina; Johannsdottir, Hrefna; Jonsdottir, Ingileif; Juliusdottir, Thorhildur; Kalsheker, Noor; Kasimov, Abdumadjit; Kemp, John P.; Kivinen, Katja; Klungs�yr, Kari; Lee, Wai K.; Melbye, Mads; Miedzybrodska, Zosia; Moffett, Ashley; Najmutdinova, Dilbar; Nishanova, Firuza; Olafsdottir, Thorunn; Perola, Markus; Broughton Pipkin, Fiona; Poston, Lucilla; Prescott, Gordon; Saevarsdottir, Saedis; Salimbayeva, Damilya; Juliet Scaife, Paula; Skotte, Line; Staines-Urias, Eleonora; Stefansson, Olafur A.; Meden S�rensen, Karina; Cecilie Vestrheim Thomsen, Liv; Tragante, Vinicius; Trogstad, Lill; Simpson, Nigel A.B.; FINNPEC Consortium; GOPEC Consortium; Aripova, Tamara; Casas, Juan P.; Dominiczak, Anna F.; Walker, James J.; Thorsteinsdottir, Unnur; Iversen, Ann-Charlotte; Feenstra, Bjarke; Lawlor, Deborah A.; Boyd, Heather Allison; Magnus, Per; Laivuori, Hannele; Zakhidova, Nodira; Svyatova, Gulnara; Stefansson, Kari; Morgan, Linda

doi:10.1038/s41467-020-19733-6

Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women

Steinthorsdottir, Valgerdur; McGinnis, Ralph; Williams, Nicholas O.; Stefansdottir, Lilja; Thorleifsson, Gudmar; Shooter, Scott; Fadista, Jo?o; Sigurdsson, Jon K.; Auro, Kirsi M.; Berezina, Galina; Borges, MariaCarolina; Bumpstead, Suzannah; Bybjerg-Grauholm, Jonas; Colgiu, Irina; Dolby, Vivien A.; Dudbridge, Frank; Engel, Stephanie M.; Franklin, Christopher S.; Frigge, Michael L.; Frisbaek, Yr; Geirsson, Reynir T.; Geller, Frank; Gretarsdottir, Solveig; Gudbjartsson, Daniel F.; Harmon, Quaker; Hougaard, David Michael; Hegay, Tatyana; Helgadottir, Anna; Hjartardottir, Sigrun; J??skel?inen, Tiina; Johannsdottir, Hrefna; Jonsdottir, Ingileif; Juliusdottir, Thorhildur; Kalsheker, Noor; Kasimov, Abdumadjit; Kemp, John P.; Kivinen, Katja; Klungs?yr, Kari; Lee, Wai K.; Melbye, Mads; Miedzybrodska, Zosia; Moffett, Ashley; Najmutdinova, Dilbar; Nishanova, Firuza; Olafsdottir, Thorunn; Perola, Markus; Broughton Pipkin, Fiona; Poston, Lucilla; Prescott, Gordon; Saevarsdottir, Saedis; Salimbayeva...

Authors

Valgerdur Steinthorsdottir

Ralph McGinnis

Nicholas O. Williams

Lilja Stefansdottir

Gudmar Thorleifsson

Scott Shooter

Jo�o Fadista

Jon K. Sigurdsson

Kirsi M. Auro

Galina Berezina

MariaCarolina Borges

Suzannah Bumpstead

Jonas Bybjerg-Grauholm

Irina Colgiu

Vivien A. Dolby

Frank Dudbridge

Stephanie M. Engel

Christopher S. Franklin

Michael L. Frigge

Yr Frisbaek

Reynir T. Geirsson

Frank Geller

Solveig Gretarsdottir

Daniel F. Gudbjartsson

Quaker Harmon

David Michael Hougaard

Tatyana Hegay

Anna Helgadottir

Sigrun Hjartardottir

Tiina J��skel�inen

Hrefna Johannsdottir

Ingileif Jonsdottir

Thorhildur Juliusdottir

Noor Kalsheker

Abdumadjit Kasimov

John P. Kemp

Katja Kivinen

Kari Klungs�yr

Wai K. Lee

Mads Melbye

Zosia Miedzybrodska

Ashley Moffett

Dilbar Najmutdinova

Firuza Nishanova

Thorunn Olafsdottir

Markus Perola

Fiona Broughton Pipkin

Lucilla Poston

Gordon Prescott

Saedis Saevarsdottir

Damilya Salimbayeva

Paula Juliet Scaife

Line Skotte

Eleonora Staines-Urias

Olafur A. Stefansson

Karina Meden S�rensen

Liv Cecilie Vestrheim Thomsen

Vinicius Tragante

Lill Trogstad

Nigel A.B. Simpson

FINNPEC Consortium

GOPEC Consortium

Tamara Aripova

Juan P. Casas

Anna F. Dominiczak

James J. Walker

Unnur Thorsteinsdottir

Ann-Charlotte Iversen

Bjarke Feenstra

Deborah A. Lawlor

Heather Allison Boyd

Per Magnus

Hannele Laivuori

Nodira Zakhidova

Gulnara Svyatova

Kari Stefansson

Linda Morgan

Citation

Steinthorsdottir, V., McGinnis, R., Williams, N. O., Stefansdottir, L., Thorleifsson, G., Shooter, S., Fadista, J., Sigurdsson, J. K., Auro, K. M., Berezina, G., Borges, M., Bumpstead, S., Bybjerg-Grauholm, J., Colgiu, I., Dolby, V. A., Dudbridge, F., Engel, S. M., Franklin, C. S., Frigge, M. L., Frisbaek, Y., …Morgan, L. (2020). Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women. Nature Communications, 11(1), https://doi.org/10.1038/s41467-020-19733-6

Journal Article Type	Article
Acceptance Date	Jul 22, 2020
Online Publication Date	Nov 25, 2020
Publication Date	2020-12
Deposit Date	Aug 17, 2020
Publicly Available Date	Dec 2, 2020
Journal	Nature Communications
Electronic ISSN	2041-1723
Publisher	Nature Publishing Group
Peer Reviewed	Peer Reviewed
Volume	11
Issue	1
DOI	https://doi.org/10.1038/s41467-020-19733-6
Keywords	General Physics and Astronomy; General Biochemistry, Genetics and Molecular Biology; General Chemistry
Public URL	https://nottingham-repository.worktribe.com/output/4839798
Publisher URL	https://www.nature.com/articles/s41467-020-19733-6
Additional Information	Received: 18 September 2019; Accepted: 26 October 2020; First Online: 25 November 2020; : V.S., L.St., G.T., J.K.S., O.A.S., M.L.F., S.G., A.H., V.T., H.J., T.Ju., T.O., S.Sa., I.J., U.T., D.F.G. and K.S., are employees of deCODE genetics/Amgen Inc. and declare competing financial interest. All remaining authors declare no competing interests.