Outputs (174)

A programme of research to set priorities and reduce uncertainties for the prevention and treatment of skin disease (2016)
Journal Article
Thomas, K. S., Batchelor, J. M., Bath-Hextall, F., Chalmers, J., Clarke, T., Crowe, S., …Williams, H. C. (2016). A programme of research to set priorities and reduce uncertainties for the prevention and treatment of skin disease. Programme Grants for Applied Research, 4(18), https://doi.org/10.3310/pgfar04180

Background Skin diseases are very common and can have a large impact on the quality of life of patients and caregivers. This programme addressed four diseases: (1) eczema, (2) vitiligo, (3) squamous cell skin cancer (SCC) and (4) pyoderma gangreno... Read More about A programme of research to set priorities and reduce uncertainties for the prevention and treatment of skin disease.

Distal junctional kyphosis in patients with Scheuermann’s disease: a retrospective radiographic analysis (2016)
Journal Article
Ghasemi, A., Stubig, T., Nasto, L. A., Ahmed, M., & Mehdian, H. (in press). Distal junctional kyphosis in patients with Scheuermann’s disease: a retrospective radiographic analysis. European Spine Journal, https://doi.org/10.1007/s00586-016-4924-3

Purpose To investigate the relationship between preoperative and postoperative spinopelvic alignment and occurrence of DJK/DJF. Study design/setting This was a retrospective observational cohort study. Patient sample The sample include... Read More about Distal junctional kyphosis in patients with Scheuermann’s disease: a retrospective radiographic analysis.

Cognitive rehabilitation for memory deficits after stroke (2016)
Journal Article
das Nair, R., Cogger, H., Worthington, E., & Lincoln, N. (2017). Cognitive rehabilitation for memory deficits after stroke. Stroke, 48(2), Article e28-e29. https://doi.org/10.1161/STROKEAHA.116.015377

Memory problems are common after a stroke, leading to difficulties in everyday life. Memory rehabilitation aims to help retrain lost functions or to teach patients strategies to compensate for them. Although some studies have reported positive outcom... Read More about Cognitive rehabilitation for memory deficits after stroke.

Potential pitfalls when denoising resting state fMRI data using nuisance regression (2016)
Journal Article
Bright, M. G., Tench, C. R., & Murphy, K. (2017). Potential pitfalls when denoising resting state fMRI data using nuisance regression. NeuroImage, 154, 159-168. https://doi.org/10.1016/j.neuroimage.2016.12.027

In resting state fMRI, it is necessary to remove signal variance associated with noise sources, leaving cleaned fMRI time-series that more accurately reflect the underlying intrinsic brain fluctuations of interest. This is commonly achieved through n... Read More about Potential pitfalls when denoising resting state fMRI data using nuisance regression.

Cardiovascular events and all-cause mortality associated with sulphonylureas compared with other antihyperglycaemic drugs: a Bayesian meta-analysis of survival data (2016)
Journal Article
Bain, S., Druyts, E., Balijepalli, C., Baxter, C. A., Currie, C. J., Das, R., …Mills, E. J. (2017). Cardiovascular events and all-cause mortality associated with sulphonylureas compared with other antihyperglycaemic drugs: a Bayesian meta-analysis of survival data. Diabetes, Obesity and Metabolism, 19(3), 329-335. https://doi.org/10.1111/dom.12821

Aim: To conduct a systematic review and meta-analysis to determine the risk of cardiovascular events and all-cause mortality associated with sulphonylureas (SUs) vs other glucose lowering drugs in patients with T2DM (T2DM. Materials and methods: A s... Read More about Cardiovascular events and all-cause mortality associated with sulphonylureas compared with other antihyperglycaemic drugs: a Bayesian meta-analysis of survival data.

Is clarithromycin a potential treatment for cachexia in people with lung cancer?: a feasibility study (2016)
Journal Article
Awan, S., Crosby, V., Potter, V., Hennig, I., Baldwin, D., Ndlovu, M., …Wilcock, A. (2017). Is clarithromycin a potential treatment for cachexia in people with lung cancer?: a feasibility study. Lung Cancer, 104, https://doi.org/10.1016/j.lungcan.2016.12.010

Clarithromycin may improve cachexia and survival in non-small cell lung cancer (NSCLC), but adequately controlled data are lacking. This study was undertaken primarily to inform the feasibility and scale of a phase III trial. Eligible consenting pati... Read More about Is clarithromycin a potential treatment for cachexia in people with lung cancer?: a feasibility study.

A comparison of humanoid and non-humanoid robots in supporting the learning of pupils with severe intellectual disabilities (2016)
Conference Proceeding
Aslam, S., Standen, P., Shopland, N., & Burton, A. (2016). A comparison of humanoid and non-humanoid robots in supporting the learning of pupils with severe intellectual disabilities. In Proceedings - 2016 International Conference on Interactive Technologies and Games (ITAG). https://doi.org/10.1109/iTAG.2016.9

Previous research has shown that the humanoid NAO robot can enhance learning as well as improve communication in children with intellectual disabilities. However, most special needs schools cannot afford the humanoid NAO robot due to high costs. Coul... Read More about A comparison of humanoid and non-humanoid robots in supporting the learning of pupils with severe intellectual disabilities.

MMP-1 activation contributes to airway smooth muscle growth and asthma severity (2016)
Journal Article
Naveed, S., Clements, D., Jackson, D. J., Philp, C., Billington, C. K., Soomro, I. N., …Johnson, S. R. (2017). MMP-1 activation contributes to airway smooth muscle growth and asthma severity. American Journal of Respiratory and Critical Care Medicine, 195(8), 1000-1009. https://doi.org/10.1164/rccm.201604-0822OC

Introduction: Matrix metalloproteinase-1 and mast cells are present in the airways of people with asthma. We hypothesised that matrix metalloproteinase-1 could be activated by mast cells and increase asthma severity. Methods: Patients with stable ast... Read More about MMP-1 activation contributes to airway smooth muscle growth and asthma severity.

Supporting Japanese mothers of children with ADHD: cultural adaptation of the New Forest Parent Training Programme (2016)
Journal Article
Shimabukuro, S., Daley, D., Thompson, M., Laver-Bradbury, C., Nakanishi, E., & Tripp, G. (2017). Supporting Japanese mothers of children with ADHD: cultural adaptation of the New Forest Parent Training Programme. Japanese Psychological Research, 59(1), 35-48. https://doi.org/10.1111/jpr.12140

International practice guidelines recommend medication and behavioral intervention as evidenced-based treatments for attention deficit hyperactivity disorder (ADHD). Currently in Japan, the availability of non pharmacological interventions for ADHD i... Read More about Supporting Japanese mothers of children with ADHD: cultural adaptation of the New Forest Parent Training Programme.

Distinct abnormalities of small bowel and regional colonic volumes in subtypes of irritable bowel syndrome revealed by MRI (2016)
Journal Article
Lam, C., Chaddock, G., Marciani, L., Costigan, C., Cox, E., Hoad, C., …Spiller, R. C. (in press). Distinct abnormalities of small bowel and regional colonic volumes in subtypes of irritable bowel syndrome revealed by MRI. American Journal of Gastroenterology, https://doi.org/10.1038/ajg.2016.538

OBJECTIVES: Non-invasive biomarkers which identify different mechanisms of disease in subgroups of irritable bowel syndrome (IBS) could be valuable. Our aim was to seek useful magnetic resonance imaging (MRI) parameters that could distinguish each IB... Read More about Distinct abnormalities of small bowel and regional colonic volumes in subtypes of irritable bowel syndrome revealed by MRI.