Human neural stem cells in patients with chronic ischaemic stroke (PISCES): a phase 1, first-in-man study
(2016)
Journal Article
Kalladka, D., Sinden, J., Pollock, K., Haig, C., McLean, J., Smith, W., McConnachie, . A., Santosh, C., Bath, P. M., Dunn, L., & Muir, K. W. (2016). Human neural stem cells in patients with chronic ischaemic stroke (PISCES): a phase 1, first-in-man study. Lancet, 388(10046), 787-796. https://doi.org/10.1016/S0140-6736%2816%2930513-X
Background: CTX0E03 is an immortalised human neural stem-cell line from which a drug product (CTX-DP) was developed for allogeneic therapy. Dose-dependent improvement in sensorimotor function in rats implanted with CTX-DP 4 weeks after middle cerebra... Read More about Human neural stem cells in patients with chronic ischaemic stroke (PISCES): a phase 1, first-in-man study.