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Outputs (51)

Care for older forensic mental health patients: A consensus guidance document (2023)
Journal Article
Tomlin, J., Walker, K., Yates, J., Dening, T., Goethals, K., Völlm, B., & Griffiths, C. (2023). Care for older forensic mental health patients: A consensus guidance document. European Psychiatry, 66(1), Article e44. https://doi.org/10.1192/j.eurpsy.2023.2413

Background It is important to investigate the needs, experiences, and outcomes of older forensic mental health inpatients. In this consensus document, we offer practitioners working with older forensic inpatients recommendations to meet the unique o... Read More about Care for older forensic mental health patients: A consensus guidance document.

Self-collected versus health-care professional taken swab for identification of vaginal-rectal colonisation with group B streptococcus in late pregnancy: a systematic review (2023)
Journal Article
Odubamowo, K., Garcia, M., Muriithi, F., Ogollah, R., Daniels, J. P., & Walker, K. F. (2023). Self-collected versus health-care professional taken swab for identification of vaginal-rectal colonisation with group B streptococcus in late pregnancy: a systematic review. European Journal of Obstetrics and Gynecology and Reproductive Biology, 286, 95-101. https://doi.org/10.1016/j.ejogrb.2023.05.027

Background Testing for group B streptococcus (GBS) requires a vaginal-rectal swab in late pregnancy. Objective A systematic review of the test accuracy of a self-collected swab compared with a health-care professional collected swab in the diagnos... Read More about Self-collected versus health-care professional taken swab for identification of vaginal-rectal colonisation with group B streptococcus in late pregnancy: a systematic review.

Women’s knowledge of and attitudes towards group B streptococcus (GBS) testing in pregnancy: a qualitative study (2023)
Journal Article
Constantinou, G., Ayers, S., Mitchell, E. J., Walker, K. F., Daniels, J., Moore, S., …Downe, S. (2023). Women’s knowledge of and attitudes towards group B streptococcus (GBS) testing in pregnancy: a qualitative study. BMC Pregnancy and Childbirth, 23, Article 339. https://doi.org/10.1186/s12884-023-05651-0

Background: 20–25% pregnant women in the UK carry group B streptococcus (GBS) which, if left undetected, is transmitted from pregnant mothers to their babies during birth in 36% of cases. This transmission leads to early onset GBS infection (EOGBS) i... Read More about Women’s knowledge of and attitudes towards group B streptococcus (GBS) testing in pregnancy: a qualitative study.

Quality of life, wellbeing, recovery, and progress for older forensic mental health patients: a qualitative investigation based on the perspectives of patients and staff (2023)
Journal Article
Walker, K., Yates, J., Dening, T., Völlm, B., Tomlin, J., & Griffiths, C. (2023). Quality of life, wellbeing, recovery, and progress for older forensic mental health patients: a qualitative investigation based on the perspectives of patients and staff. International Journal of Qualitative Studies on Health and Well-being, 18(1), Article 2202978. https://doi.org/10.1080/17482631.2023.2202978

Purpose There is a lack of research informing service requirements for older (aged≥55 years) forensic mental health patients. The aim of this research was to increase knowledge about older forensic mental health patients’ quality of life, wellbeing,... Read More about Quality of life, wellbeing, recovery, and progress for older forensic mental health patients: a qualitative investigation based on the perspectives of patients and staff.

Feasibility of a RCT of techniques for managing an impacted fetal head during emergency caesarean section: the MIDAS scoping study (2023)
Journal Article
Walker, K. F., Mitchell, E. J., Ayers, S., Jones, N. W., Ogollah, R., Wakefield, N., …Thornton, J. G. (2023). Feasibility of a RCT of techniques for managing an impacted fetal head during emergency caesarean section: the MIDAS scoping study. Health Technology Assessment, 27(6), 1-87. https://doi.org/10.3310/KUYP6832

Background: Second-stage caesarean sections, of which there are around 34,000 per year in the United Kingdom, have greater maternal and perinatal morbidity than those in the first stage. The fetal head is often deeply impacted in the maternal pelvis,... Read More about Feasibility of a RCT of techniques for managing an impacted fetal head during emergency caesarean section: the MIDAS scoping study.

The acceptability and feasibility of a randomised trial exploring approaches to managing impacted fetal head during emergency caesarean section: a qualitative study (2023)
Journal Article
Romano, G., Ayers, S., Constantinou, G., Mitchell, E. J., Plachcinski, R., Wakefield, N., & Walker, K. F. (2023). The acceptability and feasibility of a randomised trial exploring approaches to managing impacted fetal head during emergency caesarean section: a qualitative study. BMC Pregnancy and Childbirth, 23(1), Article 216. https://doi.org/10.1186/s12884-023-05444-5

Background: Caesarean sections (CS) account for 26% of all births in the UK, of which at least 5% are done at full dilatation, in the second stage of labour. Second stage CS may be complicated by the fetal head being deeply impacted in the maternal p... Read More about The acceptability and feasibility of a randomised trial exploring approaches to managing impacted fetal head during emergency caesarean section: a qualitative study.

Induction of labour (2023)
Journal Article
Azhur, S., & Walker, K. F. (2023). Induction of labour. Obstetrics, Gynaecology and Reproductive Medicine, 33(5), 121-128. https://doi.org/10.1016/j.ogrm.2023.02.001

Induction of labour describes the artificial stimulation of the onset of labour and occurs in up to 30% of pregnancies in the United Kingdom. Both mechanical and pharmacological methods of induction of labour exist. Induction of labour is associated... Read More about Induction of labour.

Techniques for managing an impacted fetal head at caesarean section: A systematic review (2022)
Journal Article
Peak, A. G., Barwise, E., & Walker, K. F. (2023). Techniques for managing an impacted fetal head at caesarean section: A systematic review. European Journal of Obstetrics and Gynecology and Reproductive Biology, 281, 12-22. https://doi.org/10.1016/j.ejogrb.2022.12.017

A complication arising at caesarean birth when the baby's head is deeply engaged in the pelvis and may be difficult to deliver, is known as an ‘impacted fetal head’. This obstetric emergency occurs in 16% of second stage caesarean sections. Multiple... Read More about Techniques for managing an impacted fetal head at caesarean section: A systematic review.

Synthetic osmotic dilators (Dilapan-S) or dinoprostone vaginal inserts (Propess) for inpatient induction of labour: A UK cost-consequence model (2022)
Journal Article
Walker, K. F., Zaher, S., Torrejon Torres, R., Saunders, S. J., Saunders, R., & Gupta, J. K. (2022). Synthetic osmotic dilators (Dilapan-S) or dinoprostone vaginal inserts (Propess) for inpatient induction of labour: A UK cost-consequence model. European Journal of Obstetrics and Gynecology and Reproductive Biology, 278, 72-76. https://doi.org/10.1016/j.ejogrb.2022.08.018

To estimate the costs of synthetic osmotic dilators (Dilapan-S) compared to dinoprostone vaginal inserts (Propess) for inpatient induction of labour (IOL). A population-level, Markov model-based cost-consequence analysis was developed to compare the... Read More about Synthetic osmotic dilators (Dilapan-S) or dinoprostone vaginal inserts (Propess) for inpatient induction of labour: A UK cost-consequence model.

Caring for women experiencing miscarriage and the importance of good communication (2022)
Journal Article
Hart, S., & Walker, K. F. (2022). Caring for women experiencing miscarriage and the importance of good communication. Obstetrics, Gynaecology and Reproductive Medicine, 32(11), 262-263. https://doi.org/10.1016/j.ogrm.2022.08.009

The importance of good quality nursing care for pregnancy loss patients can not be underestimated. Pregnancy loss is comparable to any other kind of loss and patients have noted that the nursing care they receive while in hospital can either add to o... Read More about Caring for women experiencing miscarriage and the importance of good communication.

Systems and Processes that Enable Progress for Older Forensic Mental Health Patients (2022)
Journal Article
Walker, K., Furtado, V., Yates, J., Dening, T., Völlm, B., & Griffiths, C. (2023). Systems and Processes that Enable Progress for Older Forensic Mental Health Patients. International Journal of Forensic Mental Health, 22(2), 93-104. https://doi.org/10.1080/14999013.2022.2080304

Older forensic mental health patients have complex needs and requirements; service provision is required to address mental health, offending risk and issues associated with aging (geriatric care). This study aimed to identify the systems and processe... Read More about Systems and Processes that Enable Progress for Older Forensic Mental Health Patients.

Staff perspectives on barriers to and facilitators of quality of life, health, wellbeing, recovery and reduced risk for older forensic mental-health patients: A qualitative interview study (2022)
Journal Article
Walker, K., Yates, J., Dening, T., Völlm, B., Tomlin, J., & Griffiths, C. (2022). Staff perspectives on barriers to and facilitators of quality of life, health, wellbeing, recovery and reduced risk for older forensic mental-health patients: A qualitative interview study. Journal of Health Services Research and Policy, 27(4), 287-300. https://doi.org/10.1177/13558196221094512

Objectives: There is a lack of research informing service delivery for older forensic mental health patients. This study explored service provision in forensic mental health inpatient and community services in England, investigating what is required... Read More about Staff perspectives on barriers to and facilitators of quality of life, health, wellbeing, recovery and reduced risk for older forensic mental-health patients: A qualitative interview study.

Implementation of Public Health England infection prevention and control guidance in maternity units in response to the COVID-19 pandemic (2022)
Journal Article
Hanley, S. J., Jones, A. B., Oberman, J., Baxter, E., Sharkey, D., Gray, J., & Walker, K. F. (2022). Implementation of Public Health England infection prevention and control guidance in maternity units in response to the COVID-19 pandemic. Journal of Hospital Infection, https://doi.org/10.1016/j.jhin.2022.04.018

Background: This study aimed to explore the successes and barriers to the implementation of Public Health England (PHE) infection prevention and control guidance in English maternity units during the COVID-19 pandemic. Methods: Qualitative semi-struc... Read More about Implementation of Public Health England infection prevention and control guidance in maternity units in response to the COVID-19 pandemic.

Maternity services' responses to the COVID-19 pandemic: how Public Health England guidance was implemented in practice (2022)
Journal Article
Hanley, S., Raybould, G., Baxter, E., Gray, J., Sharkey, D., & Walker, K. F. (2022). Maternity services' responses to the COVID-19 pandemic: how Public Health England guidance was implemented in practice. Journal of Hospital Infection, https://doi.org/10.1016/j.jhin.2022.04.019

Introduction: The rapidly evolving COVID-19 pandemic required systemic change in how healthcare was delivered to minimize virus transmission whilst maintaining safe service delivery. Deemed at ‘moderate-high risk’, maternity patients are an important... Read More about Maternity services' responses to the COVID-19 pandemic: how Public Health England guidance was implemented in practice.

Management of pregnancy complications in women of advanced maternal age (2022)
Journal Article
Garcia, M., Walker, K. F., & Thornton, J. G. (2022). Management of pregnancy complications in women of advanced maternal age. Obstetrics, Gynaecology and Reproductive Medicine, 32(6), 101-104. https://doi.org/10.1016/j.ogrm.2022.04.001

The average age of women at childbirth in high resource obstetric settings has been increasing steadily for approximately 30 years. Women aged 35 years or over have an increased risk of gestational hypertensive disease, gestational diabetes, placenta... Read More about Management of pregnancy complications in women of advanced maternal age.

Impacted fetal head during second stage Caesarean birth: A prospective observational study (2022)
Journal Article
Wyn Jones, N., Mitchell, E. J., Wakefield, N., Knight, M., Dorling, J., Thornton, J. G., & Walker, K. F. (2022). Impacted fetal head during second stage Caesarean birth: A prospective observational study. European Journal of Obstetrics and Gynecology and Reproductive Biology, 272, 77-81. https://doi.org/10.1016/j.ejogrb.2022.03.004

Objective: To determine the incidence of, and complication rates from, impacted fetal head at full dilatation Caesarean birth in the UK, and record what techniques were used. Design: Prospective observational study using the UK Obstetric Surveillance... Read More about Impacted fetal head during second stage Caesarean birth: A prospective observational study.

Managing an impacted fetal head at caesarean section: a UK survey of healthcare professionals and parents (2022)
Journal Article
Hanley, S. J., Walker, K. F., Wakefield, N., Plachcinski, R., Pallotti, P., Tempest, N., …Mitchell, E. J. (2022). Managing an impacted fetal head at caesarean section: a UK survey of healthcare professionals and parents. European Journal of Obstetrics and Gynecology and Reproductive Biology, 271, 88-92. https://doi.org/10.1016/j.ejogrb.2022.01.033

Objective(s) To understand current practice, expertise and training requirements for management of an impacted fetal head (IFH) at caesarean section (CS) in the UK, and whether a clinical trial of techniques to manage an IFH is acceptable. Study... Read More about Managing an impacted fetal head at caesarean section: a UK survey of healthcare professionals and parents.

COVID-19 and pregnancy: A comparison of case reports, case series and registry studies (2021)
Journal Article
Young, E. M., Green, O., Stewart, J., King, Y., O'Donoghue, K., Walker, K. F., & Thornton, J. G. (2022). COVID-19 and pregnancy: A comparison of case reports, case series and registry studies. European Journal of Obstetrics and Gynecology and Reproductive Biology, 268, 135-142. https://doi.org/10.1016/j.ejogrb.2021.12.002

Background: Selection, outcome and publication biases are well described in case reports and case series but may be less of a problem early in the appearance of a new disease when all cases might appear to be worth publishing. Objective: To use a pro... Read More about COVID-19 and pregnancy: A comparison of case reports, case series and registry studies.

Case of successfully delivered dicavitary twins in uterus didelphus (2021)
Journal Article
Barnes, E., Walker, K., Sayed, H. M., & Green, A. (2021). Case of successfully delivered dicavitary twins in uterus didelphus. BMJ Case Reports, 14(11), e245139. https://doi.org/10.1136/bcr-2021-245139

Uterus didelphus is a congenital abnormality arising from failure of fusion of Mullerian ducts, creating two separate uterine horns, two cervices and, in some cases, a vagina divided by a longitudinal septum. In this case, a 26-year-old woman with pr... Read More about Case of successfully delivered dicavitary twins in uterus didelphus.

Treatment of COVID-19 in pregnant women: A systematic review and meta-analysis (2021)
Journal Article
Giesbers, S., Goh, E., Kew, T., Allotey, J., Brizuela, V., Kara, E., …Mofenson, L. (2021). Treatment of COVID-19 in pregnant women: A systematic review and meta-analysis. European Journal of Obstetrics and Gynecology and Reproductive Biology, 267, 120-128. https://doi.org/10.1016/j.ejogrb.2021.10.007

Objective: Clinical trials evaluating pharmacological and non-pharmacological treatment of COVID-19, either excluded pregnant women or included very few women. Unlike the numerous systematic reviews on prevalence, symptoms and adverse outcomes of COV... Read More about Treatment of COVID-19 in pregnant women: A systematic review and meta-analysis.

Evidence around early induction of labor in women of advanced maternal age and those using assisted reproductive technology (2021)
Journal Article
Venkatanarayanan, N., & Walker, K. F. (2021). Evidence around early induction of labor in women of advanced maternal age and those using assisted reproductive technology. Best Practice and Research: Clinical Obstetrics and Gynaecology, 77, 42-52. https://doi.org/10.1016/j.bpobgyn.2021.08.007

Worldwide, there has been a trend toward later motherhood. Concurrently, the incidence of subfertility has been on the rise, necessitating conception using assisted reproductive technologies (ARTs). These pregnancies are considered high risk due to f... Read More about Evidence around early induction of labor in women of advanced maternal age and those using assisted reproductive technology.

Episiotomy and Initiation of Human Milk Feeds: A Retrospective Observational Study (2021)
Journal Article
Servante, J., Abramson, J., Walker, K. F., & Ojha, S. (2021). Episiotomy and Initiation of Human Milk Feeds: A Retrospective Observational Study. Breastfeeding Medicine, 16(5), 407-413. https://doi.org/10.1089/bfm.2020.0071

Objective: To investigate the association, in the United Kingdom, between having an episiotomy during childbirth and giving human milk by any modality as an infant's first feed. We also identified maternal demographic factors and perinatal experience... Read More about Episiotomy and Initiation of Human Milk Feeds: A Retrospective Observational Study.

Evaluating the influence of progesterone concentration and time of exposure on in vitro endometrial decidualisation (2021)
Journal Article
Suthaporn, S., Jayaprakasan, K., Thornton, J. G., Walker, K. F., Castellanos, M., May, S., …Maalouf, W. E. (2021). Evaluating the influence of progesterone concentration and time of exposure on in vitro endometrial decidualisation. Molecular and Cellular Endocrinology, 528, Article 111242. https://doi.org/10.1016/j.mce.2021.111242

This study aimed to evaluate the influence of progesterone (concentration and time of exposure) on endometrial decidualisation using an in vitro model cell line: Human Endometrial Stromal Cells (HESCs). HESCs exposed to progesterone (1 and 10 μM) had... Read More about Evaluating the influence of progesterone concentration and time of exposure on in vitro endometrial decidualisation.

The acceptability to women of techniques for managing an impacted fetal head at caesarean section and of randomised trials evaluating those techniques: a qualitative study (2021)
Journal Article
Romano, G., Mitchell, E., Plachcinski, R., Wakefield, N., Walker, K., & Ayers, S. (2021). The acceptability to women of techniques for managing an impacted fetal head at caesarean section and of randomised trials evaluating those techniques: a qualitative study. BMC Pregnancy and Childbirth, 21, Article 103. https://doi.org/10.1186/s12884-021-03577-z

Background This study aimed to explore women’s views on the acceptability of different techniques for managing an impacted fetal head at caesarean; and the feasibility and acceptability of conducting a trial in this area. Methods Qualitative sem... Read More about The acceptability to women of techniques for managing an impacted fetal head at caesarean section and of randomised trials evaluating those techniques: a qualitative study.

The challenges of randomised control trials in obstetrics and gynaecology (2021)
Journal Article
Harper, S. L., Thornton, J. G., & Walker, K. F. (2021). The challenges of randomised control trials in obstetrics and gynaecology. Obstetrics, Gynaecology and Reproductive Medicine, 31(2), 59-60. https://doi.org/10.1016/j.ogrm.2020.12.006

In this short article we explore some of the challenges faced by those conducting randomised trials in obstetrics and gynaecology. We discuss the current status of trials comparing induction of labour versus expectant management, so called ‘deliver o... Read More about The challenges of randomised control trials in obstetrics and gynaecology.

Fetal Movement Counting Using Optical Fibre Sensors (2020)
Journal Article
Abeywardena, C. L., Vanheusden, F. J., Walker, K. F., Arm, R., & Zhang, Q. (2021). Fetal Movement Counting Using Optical Fibre Sensors. Sensors, 21(1), 1-14. https://doi.org/10.3390/s21010048

Daily fetal movement counting based on maternal perception is widely deployed to monitor fetal wellbeing. However, the counting performed by the mother is prone to errors for various reasons. There are limited devices on the market that can provide r... Read More about Fetal Movement Counting Using Optical Fibre Sensors.

Suboptimal mid-luteal progesterone concentrations are associated with aberrant endometrial gene expression, potentially resulting in implantation failure (2020)
Journal Article
Suthaporn, S., Jayaprakasan, K., Thornton, J., Walker, K., Medrano, J. H., Castellanos, M., …Maalouf, W. E. (2021). Suboptimal mid-luteal progesterone concentrations are associated with aberrant endometrial gene expression, potentially resulting in implantation failure. Reproductive BioMedicine Online, 42(3), 595-608. https://doi.org/10.1016/j.rbmo.2020.10.018

Research question What is the difference in endometrial transcriptomics between women with normal and with low mid-luteal progesterone during the implantation window? Design An endometrial biopsy and serum progesterone concentration were taken f... Read More about Suboptimal mid-luteal progesterone concentrations are associated with aberrant endometrial gene expression, potentially resulting in implantation failure.

Maternal transmission of SARS?COV?2 to the neonate, and possible routes for such transmission: a systematic review and critical analysis (2020)
Journal Article
Walker, K., O'Donoghue, K., Grace, N., Dorling, J., Comeau, J. L., Li, W., & Thornton, J. (2020). Maternal transmission of SARS?COV?2 to the neonate, and possible routes for such transmission: a systematic review and critical analysis. BJOG: An International Journal of Obstetrics and Gynaecology, 127(11), 1324-1336. https://doi.org/10.1111/1471-0528.16362

Timing and mode of delivery with advancing maternal age (2020)
Journal Article
Walker, K. F., & Thornton, J. G. (2021). Timing and mode of delivery with advancing maternal age. Best Practice and Research: Clinical Obstetrics and Gynaecology, 70, 101-111. https://doi.org/10.1016/j.bpobgyn.2020.06.005

In 2017, 23% of all live births in the United Kingdom were to women aged over 35 years. Decisions around the timing of delivery for such women must balance the risks of prolongation of the pregnancy and of iatrogenic harm from timed delivery. Women o... Read More about Timing and mode of delivery with advancing maternal age.

The test accuracy of antenatal ultrasound definitions of fetal macrosomia to predict birth injury: a systematic review (2020)
Journal Article
Robinson, R., Walker, K. F., White, V. A., Bugg, G. J., Snell, K. I., & Jones, N. W. (2020). The test accuracy of antenatal ultrasound definitions of fetal macrosomia to predict birth injury: a systematic review. European Journal of Obstetrics and Gynecology and Reproductive Biology, 246, P79-85. https://doi.org/10.1016/j.ejogrb.2020.01.019

Objectives To determine which ultrasound measurement for predicted fetal macrosomia most accurately predicts adverse delivery and neonatal outcomes. Study Design Four biomedical databases searched for studies published after 1966. Randomised tr... Read More about The test accuracy of antenatal ultrasound definitions of fetal macrosomia to predict birth injury: a systematic review.

The strength of evidence supporting luteal phase progestogen after assisted reproduction: A systematic review with reference to trial registration and pre-specified endpoints (2019)
Journal Article
Suthaporn, S., Jayaprakasan, K., Maalouf, W., Thornton, J. G., & Walker, K. F. (2020). The strength of evidence supporting luteal phase progestogen after assisted reproduction: A systematic review with reference to trial registration and pre-specified endpoints. European Journal of Obstetrics and Gynecology and Reproductive Biology, 245, 149-161. https://doi.org/10.1016/j.ejogrb.2019.12.002

Childbirth experience questionnaire 2: Validating its use in the United Kingdom (2019)
Journal Article
Walker, K. F., Dencker, A., & Thornton, J. G. (2020). Childbirth experience questionnaire 2: Validating its use in the United Kingdom. European Journal of Obstetrics && Gynecology and Reproductive Biology: X, 5, Article 100097. https://doi.org/10.1016/j.eurox.2019.100097

© 2019 The Authors Objective: To validate the Childbirth Experience Questionnaire 2 (CEQ2) in the UK to see if it is an effective tool for evaluating labour experience. Study design: The CEQ2 and part of the Care Quality Commission Maternity Survey (... Read More about Childbirth experience questionnaire 2: Validating its use in the United Kingdom.

Advanced maternal age (2019)
Journal Article
Walker, K. F., & Thornton, J. G. (2019). Advanced maternal age. Obstetrics, Gynaecology and Reproductive Medicine, 29(9), 259-263. https://doi.org/10.1016/j.ogrm.2019.06.001

The average age of women at childbirth in industrialised nations has been increasing steadily for approximately 30 years. Women aged 35 years or over have an increased risk of gestational hypertensive disease, gestational diabetes, placenta praevia,... Read More about Advanced maternal age.

Is it time to ban oxytocin for poor labour progress? (2019)
Journal Article
Walker, K. F., & Bugg, G. (2019). Is it time to ban oxytocin for poor labour progress?. Obstetrics, Gynaecology and Reproductive Medicine, 29(6), 175-176. https://doi.org/10.1016/j.ogrm.2019.03.002

Oxytocin causes myometrial contractions and prostaglandin release. It is commonly used as an intervention for women in established labour with slow progress. However recent large randomised trials of oxytocin for this indication have shown no differe... Read More about Is it time to ban oxytocin for poor labour progress?.

Trials of antenatal corticosteroids for preterm fetal lung maturity: a review of the potential for selective outcome reporting (2019)
Journal Article
White, V. A., Walker, K. F., & Thornton, J. G. (2019). Trials of antenatal corticosteroids for preterm fetal lung maturity: a review of the potential for selective outcome reporting. European Journal of Obstetrics and Gynecology and Reproductive Biology, 236, 58-68. https://doi.org/10.1016/j.ejogrb.2019.02.031

Objective To measure the extent to which the evidence underpinning prenatal corticosteroids for preterm fetal lung maturity is at risk of bias due to selective outcome reporting. Study Design Five biomedical databases (Medline, ClinicalTrials.gov,... Read More about Trials of antenatal corticosteroids for preterm fetal lung maturity: a review of the potential for selective outcome reporting.

Maternal position in the second stage of labour for women with epidural anaesthesia (2018)
Journal Article
Walker, K. F., Kibuka, M., Thornton, J. G., & Jones, N. W. (2018). Maternal position in the second stage of labour for women with epidural anaesthesia. Cochrane Database of Systematic Reviews, 2018(11), Article CD008070. https://doi.org/10.1002/14651858.CD008070.pub4

© 2018 The Cochrane Collaboration. Background: Epidural analgesia in labour prolongs the second stage and increases instrumental delivery. It has been suggested that a more upright maternal position during all or part of the second stage may counter... Read More about Maternal position in the second stage of labour for women with epidural anaesthesia.

Development of a standardised set of metrics for monitoring site performance in multicentre randomised trials: a Delphi study (2018)
Journal Article
Whitham, D., Turzanski, J., Bradshaw, L., Clarke, M., Culliford, L., Duley, L., …Wood, J. (2018). Development of a standardised set of metrics for monitoring site performance in multicentre randomised trials: a Delphi study. Trials, 19, Article 557. https://doi.org/10.1186/s13063-018-2940-9

Background Site performance is key to the success of large multicentre randomised trials. A standardised set of clear and accessible summaries of site performance could facilitate the timely identification and resolution of potential problems, minim... Read More about Development of a standardised set of metrics for monitoring site performance in multicentre randomised trials: a Delphi study.

Monitoring performance of sites within multicentre randomised trials: a systematic review of performance metrics (2018)
Journal Article
Walker, K. F., Turzanski, J., Whitham, D., Montgomery, A., & Duley, L. (2018). Monitoring performance of sites within multicentre randomised trials: a systematic review of performance metrics. Trials, 19, Article 562. https://doi.org/10.1186/s13063-018-2941-8

© 2018 The Author(s). Background: Large multicentre trials are complex and expensive projects. A key factor for their successful planning and delivery is how well sites meet their targets in recruiting and retaining participants, and in collecting hi... Read More about Monitoring performance of sites within multicentre randomised trials: a systematic review of performance metrics.

Interventionist versus expectant care for severe pre-eclampsia between 24 and 34 weeks' gestation (2018)
Journal Article
Churchill, D., Duley, L., Thornton, J. G., Moussa, M., Ali, H. S., & Walker, K. F. (2018). Interventionist versus expectant care for severe pre-eclampsia between 24 and 34 weeks' gestation. Cochrane Database of Systematic Reviews, 2018(10), Article CD003106. https://doi.org/10.1002/14651858.CD003106.pub3

Background: Severe pre‐eclampsia can cause significant mortality and morbidity for both mother and child, particularly when it occurs remote from term, between 24 and 34 weeks' gestation. The only known cure for this disease is delivery. Some obstetr... Read More about Interventionist versus expectant care for severe pre-eclampsia between 24 and 34 weeks' gestation.

Postpartum evaluation of cardiovascular disease risk for women with pregnancies complicated by hypertension (2018)
Journal Article
Escouto, D. C., Green, A., Kurlak, L., Walker, K., Loughna, P., Chappell, L., …Bramham, K. (2018). Postpartum evaluation of cardiovascular disease risk for women with pregnancies complicated by hypertension. Pregnancy Hypertension, 13, 218-224. https://doi.org/10.1016/j.preghy.2018.06.019

Objectives: Postpartum stratification of cardiovascular risk for women with pregnancies complicated by pre-eclampsia is challenging. Our aim was to identify potential clinical and biomarker predictors of future cardiovascular risk at six weeks postpa... Read More about Postpartum evaluation of cardiovascular disease risk for women with pregnancies complicated by hypertension.

Delivery at term: when, how and why (2018)
Journal Article
Walker, K. F., & Thornton, J. (2018). Delivery at term: when, how and why. Clinics in Perinatology, 45(2), https://doi.org/10.1016/j.clp.2018.01.004

The optimal timing of delivery for the baby is 39 weeks, avoiding the morbidity associated with early term birth and reducing the risk of antepartum stillbirth. There is compelling evidence that among high-risk pregnancies and in settings where ce... Read More about Delivery at term: when, how and why.

Labour induction near term for women aged 35 or over: an economic evaluation (2017)
Journal Article
Walker, K. F., Dritsaki, M., Bugg, G., Macpherson, M., McCormick, C., Grace, N., …Thornton, J. (2017). Labour induction near term for women aged 35 or over: an economic evaluation. BJOG: An International Journal of Obstetrics and Gynaecology, 124(6), 929-934. https://doi.org/10.1111/1471-0528.14557

Objective Induction of labour at 39 weeks for nulliparous women aged 35 years and over may prevent stillbirths and does not increase caesarean births, so it may be popular. But the overall costs and benefits of such a policy have not been compared.... Read More about Labour induction near term for women aged 35 or over: an economic evaluation.

Randomized trial of labor induction in women 35 years of age or older (2016)
Journal Article
Walker, K. F., Bugg, G. J., Macpherson, M., McCormick, C., Grace, N., Wildsmith, C., …Thornton, J. (2016). Randomized trial of labor induction in women 35 years of age or older. New England Journal of Medicine, 374(9), https://doi.org/10.1056/NEJMoa1509117

BACKGROUND The risk of antepartum stillbirth at term is higher among women 35 years of age or older than among younger women. Labor induction may reduce the risk of stillbirth, but it also may increase the risk of cesarean delivery, which already is... Read More about Randomized trial of labor induction in women 35 years of age or older.

Childbirth experience questionnaire: validating its use in the United Kingdom (2015)
Journal Article
Walker, K. F., Wilson, P., Bugg, G., Dencker, A., & Thornton, J. (2015). Childbirth experience questionnaire: validating its use in the United Kingdom. BMC Pregnancy and Childbirth, 15(86), https://doi.org/10.1186/s12884-015-0513-4

BACKGROUND: The Childbirth Experience Questionnaire (CEQ) was developed in Sweden in 2010 and validated in 920 primiparous women. It has not been validated in the United Kingdom (UK). Measuring the impact of an intervention on a woman's childbirth e... Read More about Childbirth experience questionnaire: validating its use in the United Kingdom.

Discrepancies between registration and publication of randomised controlled trials: an observational study (2014)
Journal Article
Walker, K. F., Stevenson, G., & Thornton, J. (2014). Discrepancies between registration and publication of randomised controlled trials: an observational study. Journal of the Royal Society of Medicine, 5(5), https://doi.org/10.1177/2042533313517688

Abstract OBJECTIVES: To determine the consistency between information contained in the registration and publication of randomised controlled trials (RCTs). DESIGN: An observational study of RCTs published between May 2011 and May 2012 in the Brit... Read More about Discrepancies between registration and publication of randomised controlled trials: an observational study.

The dangers of the day of birth (2014)
Journal Article
Walker, K., Cohen, A., Walker, S., Allen, K., Baines, D., & Thornton, J. (2014). The dangers of the day of birth. BJOG: An International Journal of Obstetrics and Gynaecology, 121(6), 714-718. doi:10.1111/1471-0528.12544

Induction of labour versus expectant management for nulliparous women over 35 years of age: a multi-centre prospective, randomised controlled trial (2012)
Journal Article
Walker, K. F., Bugg, G., Macpherson, M., McCormick, C., Wildsmith, C., Smith, G., & Thornton, J. (2012). Induction of labour versus expectant management for nulliparous women over 35 years of age: a multi-centre prospective, randomised controlled trial. BMC Pregnancy and Childbirth, 12(Decemb), Article 8. https://doi.org/10.1186/1471-2393-12-145

Background: British women are increasingly delaying childbirth. The proportion giving birth over the age of 35 rose from 12% in 1996 to 20% in 2006. Women over this age are at a higher risk of perinatal death, and antepartum stillbirth accounts for 6... Read More about Induction of labour versus expectant management for nulliparous women over 35 years of age: a multi-centre prospective, randomised controlled trial.