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Outputs (11)

Evidence-based clinical practice guidelines on the management of pain in older people – a summary report (2020)
Journal Article
Dunham, M., Schofield, P., & Knaggs, R. (2022). Evidence-based clinical practice guidelines on the management of pain in older people – a summary report. British Journal of Pain, 16(1), 6-13. https://doi.org/10.1177/2049463720976155

Objective: The objective of this study is to develop an update of the evidence-based guidelines for the management of pain in older people. Design: Review of evidence since 2010 using a systematic and consensus approach is performed. Results: Recogni... Read More about Evidence-based clinical practice guidelines on the management of pain in older people – a summary report.

Role of pharmacists in optimising opioid therapy for chronic non-malignant pain; A systematic review (2020)
Journal Article
Iqbal, A., Knaggs, R. D., Anderson, C., & Toh, L. S. (2022). Role of pharmacists in optimising opioid therapy for chronic non-malignant pain; A systematic review. Research in Social and Administrative Pharmacy, 18(3), 2352-2366. https://doi.org/10.1016/j.sapharm.2020.11.014

Background: Opioid optimisation is a global issue in Chronic Non-malignant Pain (CNMP) management. Objective: This systematic review aims to assess the effectiveness of interventions delivered by pharmacists in outpatient clinical settings, community... Read More about Role of pharmacists in optimising opioid therapy for chronic non-malignant pain; A systematic review.

The use of intravenous lidocaine for postoperative pain and recovery: international consensus statement on efficacy and safety (2020)
Journal Article
Foo, I., Macfarlane, A. J. R., Srivastava, D., Bhaskar, A., Barker, H., Knaggs, R., …Smith, A. F. (2021). The use of intravenous lidocaine for postoperative pain and recovery: international consensus statement on efficacy and safety. Anaesthesia, 76(2), 238-250. https://doi.org/10.1111/anae.15270

Intravenous lidocaine is used widely for its effect on postoperative pain and recovery but it can be, and has been, fatal when used inappropriately and incorrectly. The risk‐benefit ratio of i.v. lidocaine varies with type of surgery and with patient... Read More about The use of intravenous lidocaine for postoperative pain and recovery: international consensus statement on efficacy and safety.

Over-The-Counter Codeine: Can Community Pharmacy Staff Nudge Customers into Its Safe and Appropriate Use? (2020)
Journal Article
Mody, S., Kirkdale, C. L., Thornley, T., Dickinson, A., Avery, A. J., Knaggs, R., …Bastable, R. (2020). Over-The-Counter Codeine: Can Community Pharmacy Staff Nudge Customers into Its Safe and Appropriate Use?. Pharmacy, 8(4), Article 185. https://doi.org/10.3390/pharmacy8040185

The misuse of opioids, including codeine which is sold over-the-counter (OTC) in United Kingdom (UK) community pharmacies, is a growing public health concern. An educational Patient Safety Card was developed and piloted to see if it nudged customers... Read More about Over-The-Counter Codeine: Can Community Pharmacy Staff Nudge Customers into Its Safe and Appropriate Use?.

An international multidisciplinary consensus statement on the prevention of opioid-related harm in adult surgical patients (2020)
Journal Article
Levy, N., Quinlan, J., El‐Boghdadly, K., Fawcett, W. J., Agarwal, V., Bastable, R. B., …Macintyre, P. E. (2020). An international multidisciplinary consensus statement on the prevention of opioid-related harm in adult surgical patients. Anaesthesia, 76(4), 520-536. https://doi.org/10.1111/anae.15262

This international multidisciplinary consensus statement was developed to provide balanced guidance on the safe peri‐operative use of opioids in adults. An international panel of healthcare professionals evaluated the literature relating to postopera... Read More about An international multidisciplinary consensus statement on the prevention of opioid-related harm in adult surgical patients.

Incidence and prevalence of primary care antidepressant prescribing in children and young people in England, 1998-2017: A population-based cohort study (2020)
Journal Article
Jack, R. H., Hollis, C., Coupland, C., Morriss, R., Knaggs, R. D., Butler, D., …Hippisley-Cox, J. (2020). Incidence and prevalence of primary care antidepressant prescribing in children and young people in England, 1998-2017: A population-based cohort study. PLoS Medicine, 17(7), Article e1003215. https://doi.org/10.1371/journal.pmed.1003215

BACKGROUND: The use of antidepressants in children and adolescents remains controversial. We examined trends over time and variation in antidepressant prescribing in children and young people in England and whether the drugs prescribed reflected UK l... Read More about Incidence and prevalence of primary care antidepressant prescribing in children and young people in England, 1998-2017: A population-based cohort study.

Particulate steroids in axial spinal blockade and the increasing role of patient consent: Les grains de sable dans l’engrenage (2020)
Journal Article
Munglani, R., Knaggs, R., & Eyre, G. (2020). Particulate steroids in axial spinal blockade and the increasing role of patient consent: Les grains de sable dans l’engrenage. British Journal of Pain, 14(2), 141-146. https://doi.org/10.1177/2049463720921199

The complexity of modern medical practice is such that it is very unlikely that on any single issue we can give a definitive answer in any circumstance, and in our view the medical debate as to the use of particulate corticosteroid medicines in axial... Read More about Particulate steroids in axial spinal blockade and the increasing role of patient consent: Les grains de sable dans l’engrenage.

Characterising the evidence base for advanced clinical practice in the UK: A scoping review protocol (2020)
Journal Article
Evans, C., Poku, B., Pearce, R., Eldridge, J., Hendrick, P., Knaggs, R., …Collier, R. (2020). Characterising the evidence base for advanced clinical practice in the UK: A scoping review protocol. BMJ Open, 10(5), Article e036192. https://doi.org/10.1136/bmjopen-2019-036192

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. Introduction A global health workforce crisis, coupled with ageing populations, wars and the rise of non-com... Read More about Characterising the evidence base for advanced clinical practice in the UK: A scoping review protocol.

Secondary care specialist visits made by children and young people prescribed antidepressants in primary care: A descriptive study using the QResearch database (2020)
Journal Article
Jack, R. H., Joseph, R. M., Coupland, C., Butler, D., Hollis, C., Morriss, R., …Hippisley-Cox, J. (2020). Secondary care specialist visits made by children and young people prescribed antidepressants in primary care: A descriptive study using the QResearch database. BMC Medicine, 18(1), https://doi.org/10.1186/s12916-020-01560-7

© 2020 The Author(s). Background: Antidepressants may be used to manage a number of conditions in children and young people including depression, anxiety, and obsessive-compulsive disorder. UK guidelines for the treatment of depression in children an... Read More about Secondary care specialist visits made by children and young people prescribed antidepressants in primary care: A descriptive study using the QResearch database.

Impact of smoking status on the efficacy of inhaled corticosteroids in chronic obstructive pulmonary disease: a systematic review (2020)
Journal Article
Sonnex, K., Alleemudder, H., & Knaggs, R. (2020). Impact of smoking status on the efficacy of inhaled corticosteroids in chronic obstructive pulmonary disease: a systematic review. BMJ Open, 10(4), https://doi.org/10.1136/bmjopen-2020-037509

Objectives: Inhaled corticosteroids (ICS) reduce exacerbation rates and the decline in lung function in people with chronic obstructive pulmonary disease (COPD). There is evidence that smoking causes ‘steroid resistance’ and thus reduces the effect o... Read More about Impact of smoking status on the efficacy of inhaled corticosteroids in chronic obstructive pulmonary disease: a systematic review.