Providing emotional support during the process of multiple sclerosis diagnosis (PrEliMS): A feasibility randomised controlled trial
(2024)
Journal Article
Das Nair, R., Mhizha-Murira, J. R., Topcu, G., Tindall, T., Bale, C., Moghaddam, N., Scheffler-Ansari, G., Drummond, A., Fitzsimmons, D., & Evangelou, N. (in press). Providing emotional support during the process of multiple sclerosis diagnosis (PrEliMS): A feasibility randomised controlled trial. Clinical Rehabilitation,
Outputs (39)
Real‐world persistence of multiple sclerosis disease‐modifying therapies (2024)
Journal Article
Tallantyre, E. C., Dobson, R., Froud, J. L. J., St John, F. A., Anderson, V. M., Arun, T., Buckley, L., Evangelou, N., Ford, H. L., Galea, I., George, S., Gray, O. M., Hibbert, A. M., Hu, M., Hughes, S. E., Ingram, G., Kalra, S., Lim, C. E., Mathews, J. T. M., McDonnell, G. V., …Robertson, N. P. (2024). Real‐world persistence of multiple sclerosis disease‐modifying therapies. European Journal of Neurology, 31(7), Article e16289. https://doi.org/10.1111/ene.16289Background and purpose: Treatment persistence is the continuation of therapy over time. It reflects a combination of treatment efficacy and tolerability. We aimed to describe real‐world rates of persistence on disease‐modifying therapies (DMTs) for p... Read More about Real‐world persistence of multiple sclerosis disease‐modifying therapies.
The Impact of COVID-19 on the Employment of People With Multiple Sclerosis: A Multi-Methods Study (2024)
Journal Article
De Dios Perez, B., Pritchard, C., Powers, K., das Nair, R., Evangelou, N., Ford, H., …Radford, K. (2024). The Impact of COVID-19 on the Employment of People With Multiple Sclerosis: A Multi-Methods Study. International Journal of Ms Care, 26(Q3), 174-186. https://doi.org/10.7224/1537-2073.2023-049Background: The COVID-19 pandemic led to approximately half of the working population in the United Kingdom being unable to work temporarily. This study aims to understand the employment needs and experiences of people with multiple sclerosis (MS) in... Read More about The Impact of COVID-19 on the Employment of People With Multiple Sclerosis: A Multi-Methods Study.
A qualitative study exploring how vocational rehabilitation for people with multiple sclerosis can be integrated within existing healthcare services in the United Kingdom (2024)
Preprint / Working Paper
De Dios Perez, B., Booth, V., das Nair, R., Evangelou, N., Hassard, J., Ford, H. L., …Radford, K. A qualitative study exploring how vocational rehabilitation for people with multiple sclerosis can be integrated within existing healthcare services in the United KingdomBackground To explore how a vocational rehabilitation (VR) intervention can be integrated within existing healthcare services for people with multiple sclerosis (MS) in the United Kingdom (UK) National Health Service (NHS). Methods Data from 37... Read More about A qualitative study exploring how vocational rehabilitation for people with multiple sclerosis can be integrated within existing healthcare services in the United Kingdom.
Risk of COVID-19 in people with multiple sclerosis who are seronegative following vaccination (2023)
Journal Article
Zaloum, S. A., Wood, C. H., Tank, P., Upcott, M., Vickaryous, N., Anderson, V., …Tallantyre, E. C. (2023). Risk of COVID-19 in people with multiple sclerosis who are seronegative following vaccination. Multiple Sclerosis Journal, 29(8), 979-989. https://doi.org/10.1177/13524585231185247Background: People with multiple sclerosis (pwMS) treated with certain disease-modifying therapies (DMTs) have attenuated IgG response following COVID-19 vaccination; however, the clinical consequences remain unclear. Objective: To report CO... Read More about Risk of COVID-19 in people with multiple sclerosis who are seronegative following vaccination.
Real-world annualized relapse rates from contemporary multiple sclerosis clinics in the UK: a retrospective multicentre cohort study (2023)
Journal Article
Papathanasiou, A., Hibbert, A., Tallantyre, E., Harding, K., Selvam, A. P., Morgan, M., …Evangelou, N. (2023). Real-world annualized relapse rates from contemporary multiple sclerosis clinics in the UK: a retrospective multicentre cohort study. Neurological Sciences, 44(10), 3629-3635. https://doi.org/10.1007/s10072-023-06838-1Background: Annualized relapse rate (ARR) is used as an outcome measure in multiple sclerosis (MS) clinical trials. Previous studies demonstrated that ARR has reduced in placebo groups between 1990 and 2012. This study aimed to estimate real-world AR... Read More about Real-world annualized relapse rates from contemporary multiple sclerosis clinics in the UK: a retrospective multicentre cohort study.
ADAMS project: a genetic Association study in individuals from Diverse Ancestral backgrounds with Multiple Sclerosis based in the UK. (2023)
Journal Article
Jacobs, B. M., Schalk, L., Dunne, A., Scalfari, A., Nandoskar, A., Gran, B., …Dobson, R. (2023). ADAMS project: a genetic Association study in individuals from Diverse Ancestral backgrounds with Multiple Sclerosis based in the UK. BMJ Open, 13(5), Article e071656. https://doi.org/10.1136/bmjopen-2023-071656Purpose Genetic studies of multiple sclerosis (MS) susceptibility and severity have focused on populations of European ancestry. Studying MS genetics in other ancestral groups is necessary to determine the generalisability of these findings. The gene... Read More about ADAMS project: a genetic Association study in individuals from Diverse Ancestral backgrounds with Multiple Sclerosis based in the UK..
An update on the use of sphingosine 1-phosphate receptor modulators for the treatment of relapsing multiple sclerosis (2023)
Journal Article
Dumitrescu, L., Papathanasiou, A., Coclitu, C., Garjani, A., Evangelou, N., Constantinescu, C. S., …Tanasescu, R. (2023). An update on the use of sphingosine 1-phosphate receptor modulators for the treatment of relapsing multiple sclerosis. Expert Opinion on Pharmacotherapy, 24(4), 495-509. https://doi.org/10.1080/14656566.2023.2178898Multiple sclerosis (MS) is an immune-mediated disorder of the CNS manifested by recurrent attacks of neurological symptoms (related to focal inflammation) and gradual disability accrual (related to progressive neurodegeneration and neuroinflammation)... Read More about An update on the use of sphingosine 1-phosphate receptor modulators for the treatment of relapsing multiple sclerosis.
Developing a Patient Care Pathway for Emotional Support around the point of Multiple Sclerosis diagnosis: A Stakeholder Engagement Study (2023)
Journal Article
Tindall, T., Topcu, G., Thomas, S., Bale, C., Evangelou, N., Drummond, A., & das Nair, R. (2023). Developing a Patient Care Pathway for Emotional Support around the point of Multiple Sclerosis diagnosis: A Stakeholder Engagement Study. Health Expectations, 26(2), 858-868. https://doi.org/10.1111/hex.13711Background: Diagnosing multiple sclerosis (MS) can be a lengthy process, which can impact psychological wellbeing, condition management, and future engagement with health services. Therefore, providing timely and appropriate emotional support may imp... Read More about Developing a Patient Care Pathway for Emotional Support around the point of Multiple Sclerosis diagnosis: A Stakeholder Engagement Study.
Paramagnetic rims are a promising diagnostic imaging biomarker in multiple sclerosis (2022)
Journal Article
Meaton, I., Altokhis, A., Allen, C. M., Clarke, M. A., Sinnecker, T., Meier, D., …Evangelou, N. (2022). Paramagnetic rims are a promising diagnostic imaging biomarker in multiple sclerosis. Multiple Sclerosis Journal, https://doi.org/10.1177/13524585221118677Background: White matter lesions (WMLs) on brain magnetic resonance imaging (MRI) in multiple sclerosis (MS) may contribute to misdiagnosis. In chronic active lesions, peripheral iron-laden macrophages appear as paramagnetic rim lesions (PRLs). Objec... Read More about Paramagnetic rims are a promising diagnostic imaging biomarker in multiple sclerosis.
Longitudinal clinical study of patients with iron rim lesions in multiple sclerosis (2022)
Journal Article
Altokhis, A. I., Hibbert, A. M., Allen, C. M., Mougin, O., Alotaibi, A., Lim, S. Y., …Evangelou, N. (2022). Longitudinal clinical study of patients with iron rim lesions in multiple sclerosis. Multiple Sclerosis Journal, 28(14), 2202-2211. https://doi.org/10.1177/13524585221114750Background: Iron rims (IRs) surrounding white matter lesions (WMLs) are suggested to predict a more severe disease course. Only small longitudinal cohorts of patients with and without iron rim lesions (IRLs) have been reported so far. Objective: To a... Read More about Longitudinal clinical study of patients with iron rim lesions in multiple sclerosis.
Decentralised clinical trials in multiple sclerosis research (2022)
Journal Article
Garjani, A., Liu, B. J.-Y., Allen, C. M., Gunzler, D. D., Gerry, S. W., Planchon, S. M., …Evangelou, N. (2023). Decentralised clinical trials in multiple sclerosis research. Multiple Sclerosis Journal, 29(3), 317-325. https://doi.org/10.1177/13524585221100401Randomised controlled trials (RCTs) play an important role in multiple sclerosis (MS) research, ensuring that new interventions are safe and efficacious before their introduction into clinical practice. Trials have been evolving to improve the robust... Read More about Decentralised clinical trials in multiple sclerosis research.
Neuropsychological evaluation and rehabilitation in multiple sclerosis (NEuRoMS): protocol for a mixed-methods, multicentre feasibility randomised controlled trial (2022)
Journal Article
Topcu, G., Smith, L., Mhizha-Murira, J. R., Goulden, N., Hoare, Z., Drummond, A., …On behalf of the NEuRoMS Collective. (2022). Neuropsychological evaluation and rehabilitation in multiple sclerosis (NEuRoMS): protocol for a mixed-methods, multicentre feasibility randomised controlled trial. Pilot and Feasibility Studies, 8(1), Article 123. https://doi.org/10.1186/s40814-022-01073-5Background: Cognitive problems affect up to 70% of people with multiple sclerosis (MS), which can negatively impact mood, ability to work, and quality of life. Addressing cognitive problems is a top 10 research priority for people with MS. Our ongoin... Read More about Neuropsychological evaluation and rehabilitation in multiple sclerosis (NEuRoMS): protocol for a mixed-methods, multicentre feasibility randomised controlled trial.
Effectiveness of acceptance and commitment therapy for improving quality of life and mood in individuals with multiple sclerosis: A systematic review and meta-analysis (2022)
Journal Article
Thompson, B., Moghaddam, N., Evangelou, N., Baufeldt, A., & das Nair, R. (2022). Effectiveness of acceptance and commitment therapy for improving quality of life and mood in individuals with multiple sclerosis: A systematic review and meta-analysis. Multiple Sclerosis and Related Disorders, 63, Article 103862. https://doi.org/10.1016/j.msard.2022.103862Objective: To review the evidence for the effectiveness of Acceptance and Commitment Therapy (ACT) intervention on quality of life and mood, for individuals with Multiple Sclerosis (MS). Method: A systematic search was conducted of PsycINFO, CINAHL,... Read More about Effectiveness of acceptance and commitment therapy for improving quality of life and mood in individuals with multiple sclerosis: A systematic review and meta-analysis.
Experiences of receiving a diagnosis of multiple sclerosis: a meta-synthesis of qualitative studies (2022)
Journal Article
Topcu, G., Mhizha-Murira, J. R., Griffiths, H., Bale, C., Drummond, A., Fitzsimmons, D., …das Nair, R. (2023). Experiences of receiving a diagnosis of multiple sclerosis: a meta-synthesis of qualitative studies. Disability and Rehabilitation, 45(5), 772-783. https://doi.org/10.1080/09638288.2022.2046187Purpose: This meta-synthesis aimed to synthesise qualitative evidence on experiences of people with Multiple Sclerosis (MS) in receiving a diagnosis, to derive a conceptual understanding of adjustment to MS diagnosis. Methods: Five electronic databas... Read More about Experiences of receiving a diagnosis of multiple sclerosis: a meta-synthesis of qualitative studies.
Impact of mass vaccination on SARS-CoV-2 infections among multiple sclerosis patients taking immunomodulatory disease-modifying therapies in England (2021)
Journal Article
Garjani, A., Patel, S., Bharkhada, D., Rashid, W., Coles, A., Law, G. R., & Evangelou, N. (2022). Impact of mass vaccination on SARS-CoV-2 infections among multiple sclerosis patients taking immunomodulatory disease-modifying therapies in England. Multiple Sclerosis and Related Disorders, 57, Article 103458. https://doi.org/10.1016/j.msard.2021.103458Background: Contradicting assumptions have been made about the effectiveness of SARS-CoV-2 vaccines in patients with multiple sclerosis (MS) receiving immunomodulatory disease-modifying therapies (DMTs) based on the quantification of humoral and cell... Read More about Impact of mass vaccination on SARS-CoV-2 infections among multiple sclerosis patients taking immunomodulatory disease-modifying therapies in England.
Recovery From COVID-19 in Multiple Sclerosis: A Prospective and Longitudinal Cohort Study of the United Kingdom Multiple Sclerosis Register (2021)
Journal Article
Garjani, A., Middleton, R. M., Nicholas, R., & Evangelou, N. (2022). Recovery From COVID-19 in Multiple Sclerosis: A Prospective and Longitudinal Cohort Study of the United Kingdom Multiple Sclerosis Register. Neurology, Neuroimmunology and Neuroinflammation, 9(1), Article e1118. https://doi.org/10.1212/nxi.0000000000001118Background and Objectives: To understand the course of recovery from coronavirus disease 2019 (COVID-19) among patients with multiple sclerosis (MS) and to determine its predictors, including patients' pre–COVID-19 physical and mental health status.... Read More about Recovery From COVID-19 in Multiple Sclerosis: A Prospective and Longitudinal Cohort Study of the United Kingdom Multiple Sclerosis Register.
COVID-19 Vaccine Response in People with Multiple Sclerosis (2021)
Journal Article
Tallantyre, E. C., Vickaryous, N., Anderson, V., Asardag, A. N., Baker, D., Bestwick, J., …Dobson, R. (2022). COVID-19 Vaccine Response in People with Multiple Sclerosis. Annals of Neurology, 91(1), 89-100. https://doi.org/10.1002/ana.26251Objective: The purpose of this study was to investigate the effect of disease modifying therapies on immune response to severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) vaccines in people with multiple sclerosis (MS). Methods: Four hundre... Read More about COVID-19 Vaccine Response in People with Multiple Sclerosis.
COVID-19 in Multiple Sclerosis: Clinically reported outcomes from the UK Multiple Sclerosis Register (2021)
Journal Article
Middleton, R. M., Craig, E. M., Rodgers, W. J., Tuite-Dalton, K., Garjani, A., Evangelou, N., …UK Multiple Sclerosis Register Research Group. (2021). COVID-19 in Multiple Sclerosis: Clinically reported outcomes from the UK Multiple Sclerosis Register. Multiple Sclerosis and Related Disorders, 56, Article 103317. https://doi.org/10.1016/j.msard.2021.103317Background: In March 2020, the United Kingdom Multiple Sclerosis Register (UKMSR) established an electronic case return form, designed collaboratively by MS neurologists, to record data about COVID-19 infections in people with MS (pwMS). Objectives:... Read More about COVID-19 in Multiple Sclerosis: Clinically reported outcomes from the UK Multiple Sclerosis Register.
Mild traumatic brain injury impairs the coordination of intrinsic and motor-related neural dynamics (2021)
Journal Article
Rier, L., Zamyadi, R., Zhang, J., Emami, Z., Seedat, Z. A., Mocanu, S., …Dunkley, B. T. (2021). Mild traumatic brain injury impairs the coordination of intrinsic and motor-related neural dynamics. NeuroImage: Clinical, 32, Article 102841. https://doi.org/10.1016/j.nicl.2021.102841Mild traumatic brain injury (mTBI) poses a considerable burden on healthcare systems. Whilst most patients recover quickly, a significant number suffer from sequelae that are not accompanied by measurable structural damage. Understanding the neural u... Read More about Mild traumatic brain injury impairs the coordination of intrinsic and motor-related neural dynamics.
Acceptance-based telephone support around the time of transition to secondary progressive multiple sclerosis: A feasibility randomised controlled trial (2021)
Journal Article
Meek, C., Moghaddam, N. G., Evangelou, N., Oates, L. L., Topcu, G., Allen, C., & das Nair, R. (2021). Acceptance-based telephone support around the time of transition to secondary progressive multiple sclerosis: A feasibility randomised controlled trial. Journal of Contextual Behavioral Science, 21, 158-170. https://doi.org/10.1016/j.jcbs.2021.07.001Introduction Transitioning to secondary progressive multiple sclerosis (SPMS) is a difficult time for people, fraught with psychological uncertainty and an increase in physical disability. In parallel, healthcare appointments become less frequent, m... Read More about Acceptance-based telephone support around the time of transition to secondary progressive multiple sclerosis: A feasibility randomised controlled trial.
Cognitive measures used in adults with multiple sclerosis: A systematic review (2021)
Journal Article
Elwick, H., Topcu, G., Allen, C. M., Drummond, A., Evangelou, N., & Das Nair, R. (2022). Cognitive measures used in adults with multiple sclerosis: A systematic review. Neuropsychological Rehabilitation, 32(9), 2464-2481. https://doi.org/10.1080/09602011.2021.1936080Cognitive problems are common in people with Multiple Sclerosis (MS), and researchers and clinicians have used a vast array of measures to assess cognition. Our aim was to systematically identify cognitive measures routinely used in MS research, and... Read More about Cognitive measures used in adults with multiple sclerosis: A systematic review.
Mental health of people with multiple sclerosis during the COVID-19 outbreak: A prospective cohort and cross-sectional case–control study of the UK MS Register (2021)
Journal Article
Garjani, A., Hunter, R., Law, G. R., Middleton, R. M., Tuite-Dalton, K. A., Dobson, R., …das Nair, R. (2022). Mental health of people with multiple sclerosis during the COVID-19 outbreak: A prospective cohort and cross-sectional case–control study of the UK MS Register. Multiple Sclerosis Journal, 28(7), 1060-1071. https://doi.org/10.1177/13524585211020435Background: People with MS (pwMS) have had higher rates of anxiety and depression than the general population before the COVID-19 pandemic, placing them at higher risk of experiencing poor psychological wellbeing during the pandemic. Objective: To as... Read More about Mental health of people with multiple sclerosis during the COVID-19 outbreak: A prospective cohort and cross-sectional case–control study of the UK MS Register.
Magnetoencephalography abnormalities in adult mild traumatic brain injury: a systematic review (2021)
Journal Article
Allen, C. M., Halsey, L., Topcu, G., Rier, L., Gascoyne, L. E., Scadding, J. W., …Evangelou, N. (2021). Magnetoencephalography abnormalities in adult mild traumatic brain injury: a systematic review. NeuroImage: Clinical, 31, Article 102697. https://doi.org/10.1016/j.nicl.2021.102697
COVID-19 is associated with new symptoms of multiple sclerosis that are prevented by disease modifying therapies (2021)
Journal Article
Garjani, A., Middleton, R. M., Hunter, R., Tuite-Dalton, K. A., Coles, A., Dobson, R., …Evangelou, N. (2021). COVID-19 is associated with new symptoms of multiple sclerosis that are prevented by disease modifying therapies. Multiple Sclerosis and Related Disorders, 52, Article 102939. https://doi.org/10.1016/j.msard.2021.102939Background Infections can trigger exacerbations of multiple sclerosis (MS). The effects of the coronavirus disease 2019 (COVID-19) on MS are not known. The aim of this study was to understand the impact of COVID-19 on new and pre-existing symptoms... Read More about COVID-19 is associated with new symptoms of multiple sclerosis that are prevented by disease modifying therapies.
Prognostication and contemporary management of clinically isolated syndrome (2020)
Journal Article
Allen, C. M., Mowry, E., Tintore, M., & Evangelou, N. (2021). Prognostication and contemporary management of clinically isolated syndrome. Journal of Neurology, Neurosurgery and Psychiatry, 92(4), 391-397. https://doi.org/10.1136/jnnp-2020-323087Clinically isolated syndrome (CIS) patients present with a single attack of inflammatory demyelination of the central nervous system. Recent advances in multiple sclerosis (MS) diagnostic criteria have expanded the number of CIS patients eligible for... Read More about Prognostication and contemporary management of clinically isolated syndrome.
Developing a clinical pathway to identify and manage cognitive problems in Multiple Sclerosis: Qualitative findings from patients, family members, charity volunteers, clinicians and healthcare commissioners (2020)
Journal Article
Smith, L., Elwick, H., Mhizha-Murira, J., Topcu, G., Bale, C., Evangelou, N., …Das Nair, R. (2021). Developing a clinical pathway to identify and manage cognitive problems in Multiple Sclerosis: Qualitative findings from patients, family members, charity volunteers, clinicians and healthcare commissioners. Multiple Sclerosis and Related Disorders, 49, Article 102563. https://doi.org/10.1016/j.msard.2020.102563Background: Cognitive problems are a common and debilitating symptom of multiple sclerosis (MS). Screening and treatment for cognitive problems are recommended, however these are not routinely delivered in UK clinics. We collected and synthesised... Read More about Developing a clinical pathway to identify and manage cognitive problems in Multiple Sclerosis: Qualitative findings from patients, family members, charity volunteers, clinicians and healthcare commissioners.
Psychosocial adjustment to multiple sclerosis diagnosis: A meta-review of systematic reviews (2020)
Journal Article
Topcu, G., Griffiths, H., Bale, C., Trigg, E., Clarke, S., Potter, K.-J., …das Nair, R. (2020). Psychosocial adjustment to multiple sclerosis diagnosis: A meta-review of systematic reviews. Clinical Psychology Review, 82, Article 101923. https://doi.org/10.1016/j.cpr.2020.101923This meta-review aimed to synthesise evidence on psychosocial adjustment to multiple sclerosis, to identify available treatment models and services for recently diagnosed individuals, and to explore their effectiveness. MEDLINE, CINAHL, EMBASE, PsycI... Read More about Psychosocial adjustment to multiple sclerosis diagnosis: A meta-review of systematic reviews.
Self-diagnosed COVID-19 in people with multiple sclerosis: a community-based cohort of the UK MS Register (2020)
Journal Article
Evangelou, N., Garjani, A., Das Nair, R., Hunter, R., Tuite-Dalton, K., Craig, E., …Nicholas, R. (2021). Self-diagnosed COVID-19 in people with multiple sclerosis: a community-based cohort of the UK MS Register. Journal of Neurology, Neurosurgery and Psychiatry, 92(1), 107-109. https://doi.org/10.1136/jnnp-2020-324449
Self-help Acceptance and Commitment Therapy for Carers of People with Multiple Sclerosis: A Feasibility Randomised Controlled Trial (2020)
Journal Article
Potter, K.-J., Golijana‑Moghaddam, N., Evangelou, N., Mhizha-Murira, J., & Nair, R. (2021). Self-help Acceptance and Commitment Therapy for Carers of People with Multiple Sclerosis: A Feasibility Randomised Controlled Trial. Journal of Clinical Psychology in Medical Settings, 28, 279-294. https://doi.org/10.1007/s10880-020-09711-xIntroduction: Acceptance and Commitment Therapy (ACT) is an established psychological therapy, but its effectiveness for carers of people with Multiple Sclerosis experiencing carer-related strain has not been established. This study assessed the... Read More about Self-help Acceptance and Commitment Therapy for Carers of People with Multiple Sclerosis: A Feasibility Randomised Controlled Trial.
Behavioural activation treatment for depression in individuals with neurological conditions: a systematic review (2019)
Journal Article
Oates, L. L., Moghaddam, N., Evangelou, N., & das Nair, R. (2020). Behavioural activation treatment for depression in individuals with neurological conditions: a systematic review. Clinical Rehabilitation, 34(3), 310-319. https://doi.org/10.1177/0269215519896404© The Author(s) 2019. Objective: To evaluate the effectiveness of behavioural activation interventions for people with neurological conditions with comorbid depression, and explore content and adaptations. Data sources: PsycINFO, MEDLINE, CINAHL, AME... Read More about Behavioural activation treatment for depression in individuals with neurological conditions: a systematic review.
Clinical observation during alemtuzumab administration (2019)
Journal Article
Allen, C. M., Feng, J. J., Willis, M. D., McGinley, M., Ontaneda, D., Tallantyre, E. C., & Evangelou, N. (2020). Clinical observation during alemtuzumab administration. Multiple Sclerosis and Related Disorders, 37, Article 101412. https://doi.org/10.1016/j.msard.2019.101412
Evaluation of the Central Vein Sign as a Diagnostic Imaging Biomarker in Multiple Sclerosis (2019)
Journal Article
Sinnecker, T., Clarke, M. A., Meier, D., Enzinger, C., Calabrese, M., De Stefano, N., …MAGNIMS Study Group. (2019). Evaluation of the Central Vein Sign as a Diagnostic Imaging Biomarker in Multiple Sclerosis. JAMA Neurology, 76(12), 1446-1456. https://doi.org/10.1001/jamaneurol.2019.2478© 2019 American Medical Association. All rights reserved. Importance: The central vein sign has been proposed as a specific imaging biomarker for distinguishing between multiple sclerosis (MS) and not MS, mainly based on findings from ultrahigh-field... Read More about Evaluation of the Central Vein Sign as a Diagnostic Imaging Biomarker in Multiple Sclerosis.
Ultra-high-field arterial spin labeling MRI for non-contrast assessment of cortical lesion perfusion in multiple sclerosis (2018)
Journal Article
Drury, R. J., Falah, Y., Gowland, P. A., Evangelou, N., Bright, M. G., & Francis, S. T. (2019). Ultra-high-field arterial spin labeling MRI for non-contrast assessment of cortical lesion perfusion in multiple sclerosis. European Radiology, 29(4), 2027–2033. https://doi.org/10.1007/s00330-018-5707-5Objectives Assess the feasibility of using an optimised ultra-high-field high-spatial-resolution low-distortion ASL MRI acquisition to measure focal haemodynamic pathology in cortical lesions (CLs) in Multiple Sclerosis (MS). Methods Twelve... Read More about Ultra-high-field arterial spin labeling MRI for non-contrast assessment of cortical lesion perfusion in multiple sclerosis.
Ultra-high-field arterial spin labelling MRI for non-contrast assessment of cortical lesion perfusion in multiple sclerosis (2018)
Journal Article
Dury, R. J., Falah, Y., Gowland, P. A., Evangelou, N., Bright, M. G., & Francis, S. T. (2019). Ultra-high-field arterial spin labelling MRI for non-contrast assessment of cortical lesion perfusion in multiple sclerosis. European Radiology, 29(4), 2027-2033. https://doi.org/10.1007/s00330-018-5707-5© 2018, The Author(s). Objectives: To assess the feasibility of using an optimised ultra-high-field high-spatial-resolution low-distortion arterial spin labelling (ASL) MRI acquisition to measure focal haemodynamic pathology in cortical lesions (CLs)... Read More about Ultra-high-field arterial spin labelling MRI for non-contrast assessment of cortical lesion perfusion in multiple sclerosis.
The MRI central vein marker: differentiating PPMS from RRMS and ischaemic SVD (2018)
Journal Article
Samaraweera, A. P., Falah, Y., Pitot, A., Dineen, R. A., Morgan, P. S., & Evangelou, N. (2018). The MRI central vein marker: differentiating PPMS from RRMS and ischaemic SVD. Neurology, Neuroimmunology and Neuroinflammation, 5(6), Article e496. https://doi.org/10.1212/NXI.0000000000000496© 2018 The Author(s). Objective To determine whether the assessment of brain white matter lesion (WML) central veins differentiate patients with primary progressive MS (PPMS) from relapsing-remitting MS (RRMS) and ischemic small vessel disease (SVD)... Read More about The MRI central vein marker: differentiating PPMS from RRMS and ischaemic SVD.
MRI criteria for the diagnosis of multiple sclerosis: MAGNIMS consensus guidelines (2016)
Journal Article
Multiple sclerosis findings in the spinal cord (2007)
Journal Article
Edwards, L., Tench, C., Gilmore, C., Evangelou, N., & Constantinescu, C. (2007). Multiple sclerosis findings in the spinal cord. Expert Review of Neurotherapeutics, 7(9), 1203-1211. https://doi.org/10.1586/14737175.7.9.1203