Professor Lucy Fairclough's Outputs (8)

Life-threatening hypersensitivity pneumonitis secondary to e-cigarettes (2019)
Journal Article
Nair, N., Hurley, M., Gates, S., Davies, P., Chen, I. L., Todd, I., Fairclough, L., Bush, A., & Bhatt, M. (2020). Life-threatening hypersensitivity pneumonitis secondary to e-cigarettes. Archives of Disease in Childhood, 105(11), 1114-1116. https://doi.org/10.1136/archdischild-2019-317889

© Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ. We report a case of hypersensitivity pneumonitis (HP) in a young person secondary to vaping. He presented with a putative diagnosis of asthma... Read More about Life-threatening hypersensitivity pneumonitis secondary to e-cigarettes.

Mood and influenza vaccination in older adults: A randomized controlled trial. (2019)
Journal Article
Ayling, K., Fairclough, L., Buchanan, H., Wetherell, M. A., & Vedhara, K. (2019). Mood and influenza vaccination in older adults: A randomized controlled trial. Health Psychology, 38(11), 984-996. https://doi.org/10.1037/hea0000786

Objective: Positive mood on the day of vaccination has been associated with subsequent antibody responses to the influenza vaccine in older adults. The primary aim of this trial was to examine whether a brief intervention was able to enhance positive... Read More about Mood and influenza vaccination in older adults: A randomized controlled trial..

Towards a surrogate system to express human lipid binding TCRs (2019)
Journal Article
Wang, R., Pscheid, R., Ghumra, A., Kan, L. Y. L., Cochrane, S., Fairclough, L., & Alcocer, M. J. C. (2019). Towards a surrogate system to express human lipid binding TCRs. Biotechnology Letters, 41(10), 1095-1104. https://doi.org/10.1007/s10529-019-02713-2

Background

Previously we reported that natural nut lipids were necessary for sensitization and that natural killer T cells (NKTs) must play a critical role in the development of food allergic responses. A major bottleneck in further understanding... Read More about Towards a surrogate system to express human lipid binding TCRs.

Cigarette smoking differentially affects immunoglobulin class levels in serum and saliva: An investigation and review (2019)
Journal Article
Tarbiah, N., Todd, I., Tighe, P. J., & Fairclough, L. C. (2019). Cigarette smoking differentially affects immunoglobulin class levels in serum and saliva: An investigation and review. Basic and Clinical Pharmacology and Toxicology, 125(5), 474-483. https://doi.org/10.1111/bcpt.13278

The aim of the present study was to compare concentrations of IgG, IgA, IgM and IgD in both serum and saliva samples from smoking and non-smoking subjects using a protein microarray assay. The findings were also compared to previous studies. Serum an... Read More about Cigarette smoking differentially affects immunoglobulin class levels in serum and saliva: An investigation and review.

Psychological interventions as vaccine adjuvants: A systematic review (2019)
Journal Article
Vedhara, K., Ayling, K., Sunger, K., Caldwell, D. M., Halliday, V., Fairclough, L., Avery, A., Robles, L., Garibaldi, J., Welton, N. J., & Royal, S. (2019). Psychological interventions as vaccine adjuvants: A systematic review. Vaccine, 37(25), 3255-3266. https://doi.org/10.1016/j.vaccine.2019.04.091

Objectives: The effectiveness of vaccines is known to be altered by a range of psychological factors. We conducted a systematic review to evaluate the effects of psychological interventions on the ability of vaccines to protect against disease, as me... Read More about Psychological interventions as vaccine adjuvants: A systematic review.

Patients with TNF Receptor Associated Periodic Syndrome (TRAPS) are hypersensitive to Toll‐like receptor 9 stimulation (2019)
Journal Article
Negm, O. H., Singh, S., Abduljabbar, W., Hamed, M. R., Radford, P., McDermott, E. M., Drewe, E., Fairclough, L., Todd, I., & Tighe, P. J. (2019). Patients with TNF Receptor Associated Periodic Syndrome (TRAPS) are hypersensitive to Toll‐like receptor 9 stimulation. Clinical and Experimental Immunology, 197(3), 352-360. https://doi.org/10.1111/cei.13306

Tumour necrosis factor receptor‐associated periodic syndrome (TRAPS) is an hereditary autoinflammatory disorder characterised by recurrent episodes of fever and inflammation. It is associated with autosomal dominant mutations in TNFRSF1A, which encod... Read More about Patients with TNF Receptor Associated Periodic Syndrome (TRAPS) are hypersensitive to Toll‐like receptor 9 stimulation.

Immunological and pathological effects of electronic cigarettes (2019)
Journal Article
Chen, I. L., Todd, I., & Fairclough, L. C. (2019). Immunological and pathological effects of electronic cigarettes. Basic and Clinical Pharmacology and Toxicology, 125(3), 237-252. https://doi.org/10.1111/bcpt.13225

© 2019 The Authors. Basic & Clinical Pharmacology & Toxicology published by John Wiley & Sons Ltd on behalf of Nordic Association for the Publication of BCPT (former Nordic Pharmacological Society). Electronic cigarettes (E-cigarettes) are cons... Read More about Immunological and pathological effects of electronic cigarettes.

Atopic dermatitis and autoimmunity: the occurrence of autoantibodies and their association with disease severity (2019)
Journal Article
Holmes, J., Fairclough, L., & Todd, I. (2019). Atopic dermatitis and autoimmunity: the occurrence of autoantibodies and their association with disease severity. Archives of Dermatological Research, 311(3), 141-162. https://doi.org/10.1007/s00403-019-01890-4

Atopic dermatitis (AD) is a widespread condition that appears to be increasing in prevalence and severity worldwide, yet the underlying mechanisms are not well understood. Recent research has identified various similarities between AD and autoimmune... Read More about Atopic dermatitis and autoimmunity: the occurrence of autoantibodies and their association with disease severity.