I. Ling Chen
Immunological and pathological effects of electronic cigarettes
Chen, I. Ling; Todd, Ian; Fairclough, Lucy C.
Abstract
© 2019 The Authors. Basic & Clinical Pharmacology & Toxicology published by John Wiley & Sons Ltd on behalf of Nordic Association for the Publication of BCPT (former Nordic Pharmacological Society). Electronic cigarettes (E-cigarettes) are considered a preferable alternative to conventional cigarettes due to the lack of combustion and the absence of tobacco-specific toxicants. E-cigarettes have rapidly gained in popularity in recent years amongst both existing smokers and previous non-smokers. However, a growing literature demonstrates that E-cigarettes are not as safe as generally believed. Here, we discuss the immunological, and other, deleterious effects of E-cigarettes on a variety of cell types and host defence mechanisms in humans and in murine models. We review not only the effects of complete E-cigarette liquids, but also each of the main components—nicotine, humectants and flavourings. This MiniReview thus highlights the possible role of E-cigarettes in the pathogenesis of disease and raises awareness of the potential harm that E-cigarettes may cause.
Citation
Chen, I. L., Todd, I., & Fairclough, L. C. (2019). Immunological and pathological effects of electronic cigarettes. Basic and Clinical Pharmacology and Toxicology, 125(3), 237-252. https://doi.org/10.1111/bcpt.13225
| Journal Article Type | Article |
|---|---|
| Acceptance Date | Mar 4, 2019 |
| Online Publication Date | Mar 12, 2019 |
| Publication Date | 2019-09 |
| Deposit Date | Mar 8, 2019 |
| Publicly Available Date | Jun 10, 2019 |
| Journal | Basic and Clinical Pharmacology and Toxicology |
| Print ISSN | 1742-7835 |
| Electronic ISSN | 1742-7843 |
| Publisher | Wiley |
| Peer Reviewed | Peer Reviewed |
| Volume | 125 |
| Issue | 3 |
| Pages | 237-252 |
| DOI | https://doi.org/10.1111/bcpt.13225 |
| Keywords | Toxicology; Pharmacology; General Medicine |
| Public URL | https://nottingham-repository.worktribe.com/output/1620903 |
| Publisher URL | https://onlinelibrary.wiley.com/doi/abs/10.1111/bcpt.13225?af=R |
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Publisher Licence URL
http://creativecommons.org/licenses/by-nc-nd/4.0/