All Outputs (45223)

The efficacy of ‘static’ training interventions for improving indices of cardiorespiratory fitness in premenopausal females (2018)
Journal Article
Herrod, P. J. J., Blackwell, J. E. M., Moss, B. F., Gates, A., Atherton, P. J., Lund, J. N., …Phillips, B. E. (2019). The efficacy of ‘static’ training interventions for improving indices of cardiorespiratory fitness in premenopausal females. European Journal of Applied Physiology, 119(3), 645-652. https://doi.org/10.1007/s00421-018-4054-1

PURPOSE:
Cardiovascular disease (CVD) is the leading cause of death worldwide. Many risk factors for CVD can be modified pharmacologically; however, uptake of medications is low, especially in asymptomatic people. Exercise is also effective at reduc... Read More about The efficacy of ‘static’ training interventions for improving indices of cardiorespiratory fitness in premenopausal females.

An experimental evaluation of the use of Δ13C as a proxy for palaeoatmospheric CO2 (2018)
Journal Article
Lomax, B. H., Lake, J. A., Leng, M. J., & Jardine, P. E. (2019). An experimental evaluation of the use of Δ13C as a proxy for palaeoatmospheric CO2. Geochimica et Cosmochimica Acta, 247, 162-174. https://doi.org/10.1016/j.gca.2018.12.026

Understanding changes in atmospheric CO2 over geological time via the development of well constrained and tested proxies is of increasing importance within the Earth sciences. Recently a new proxy (identified as the C3 proxy) has been proposed that i... Read More about An experimental evaluation of the use of Δ13C as a proxy for palaeoatmospheric CO2.

Sound therapy (using amplification devices and/or sound generators) for tinnitus (2018)
Journal Article
Sereda, M., Xia, J., El Refaie, A., Hall, D. A., & Hoare, D. J. (2018). Sound therapy (using amplification devices and/or sound generators) for tinnitus. Cochrane Database of Systematic Reviews, 2018(12), Article CD013094. https://doi.org/10.1002/14651858.CD013094.pub2

BACKGROUND: Tinnitus affects 10% to 15% of the adult population, with about 20% of these experiencing symptoms that negatively affect quality of life. In England alone there are an estimated ¾ million general practice consultations every year where t... Read More about Sound therapy (using amplification devices and/or sound generators) for tinnitus.

Evaluating the recently imposed English compulsory dog microchipping policy. Evidence from an English Local Authority (2018)
Journal Article
Siettou, C. (2019). Evaluating the recently imposed English compulsory dog microchipping policy. Evidence from an English Local Authority. Preventive Veterinary Medicine, 163, 31-36. https://doi.org/10.1016/j.prevetmed.2018.12.015

This is the first empirical study examining the effectiveness of the newly imposed English compulsory dog microchipping policy. A dataset of 2974 records was retrieved from an English local authority’s website. Records were from the period 2010–2018... Read More about Evaluating the recently imposed English compulsory dog microchipping policy. Evidence from an English Local Authority.

Low-field, benchtop NMR spectroscopy as a potential tool for point-of-care diagnostics of metabolic conditions: Validation, protocols and computational models (2018)
Journal Article
Percival, B. C., Grootveld, M., Gibson, M., Osman, Y., Molinari, M., Jafari, F., …Wilson, P. B. (2019). Low-field, benchtop NMR spectroscopy as a potential tool for point-of-care diagnostics of metabolic conditions: Validation, protocols and computational models. High-Throughput, 8(1), Article 2. https://doi.org/10.3390/ht8010002

Novel sensing technologies for liquid biopsies offer promising prospects for the early detection of metabolic conditions through omics techniques. Indeed, high-field nuclear magnetic resonance (NMR) facilities are routinely used for metabolomics inve... Read More about Low-field, benchtop NMR spectroscopy as a potential tool for point-of-care diagnostics of metabolic conditions: Validation, protocols and computational models.

Phase-shift-modulation for a current-fed isolated DC-DC converter in more electric aircraft (2018)
Journal Article
Chen, L., Tarisciotti, L., Costabeber, A., Guan, Q., Wheeler, P., & Zanchetta, P. (2019). Phase-shift-modulation for a current-fed isolated DC-DC converter in more electric aircraft. IEEE Transactions on Power Electronics, 34(9), 8528-8543. https://doi.org/10.1109/tpel.2018.2889861

A Phase-Shift-Modulation (PSM) technique is proposed for an Active-Bridge-Active-Clamp (ABAC) topology. This topology is aimed for high power more-electric-aircraft applications. The proposed PSM has a complete switching harmonics cancellation on the... Read More about Phase-shift-modulation for a current-fed isolated DC-DC converter in more electric aircraft.

Current-Fed Isolated DC/DC Converter for Future Aerospace Microgrids (2018)
Journal Article
Tarisciotti, L., Costabeber, A., Chen, L., Walker, A., & Galea, M. (2019). Current-Fed Isolated DC/DC Converter for Future Aerospace Microgrids. IEEE Transactions on Industry Applications, 55(3), 2823-2832. https://doi.org/10.1109/tia.2018.2889845

High-performance power conversion equipment is currently gaining an increasing interest for aircraft applications. In particular, isolated bidirectional dc/dc converters are often proposed for modern aircraft distribution systems. A current-fed isola... Read More about Current-Fed Isolated DC/DC Converter for Future Aerospace Microgrids.

Exceptional Performance of Hierarchical Ni-Fe (hydr)oxide@NiCu Electrocatalysts for Water Splitting (2018)
Journal Article
Zhou, Y., Wang, Z., Pan, Z., Liu, L., Xi, J., Luo, X., & Shen, Y. (2019). Exceptional Performance of Hierarchical Ni-Fe (hydr)oxide@NiCu Electrocatalysts for Water Splitting. Advanced Materials, 31(8), Article 1806769. https://doi.org/10.1002/adma.201806769

Developing low‐cost bifunctional electrocatalysts with superior activity for both the oxygen evolution reaction (OER) and hydrogen evolution reaction (HER) is of great importance for the widespread application of the water splitting technique. In thi... Read More about Exceptional Performance of Hierarchical Ni-Fe (hydr)oxide@NiCu Electrocatalysts for Water Splitting.

Cell response to plasma electrolytic oxidation surface-modified low-modulus β-type titanium alloys (2018)
Journal Article
Tanase, C., Golozar, M., Best, S., & Brooks, R. (2021). Cell response to plasma electrolytic oxidation surface-modified low-modulus β-type titanium alloys. Colloids and Surfaces B: Biointerfaces, 176, 176-184. https://doi.org/10.1016/j.colsurfb.2018.12.064

Plasma electrolytic oxidation (PEO) has been demonstrated to be an effective surface treatment for enhancing the osteoconduction and osseointegration of commercially pure α-Ti (CP α-Ti) dental implant materials for clinical application. To explore th... Read More about Cell response to plasma electrolytic oxidation surface-modified low-modulus β-type titanium alloys.

A general framework for optimizing arterial spin labeling MRI experiments (2018)
Journal Article
Woods, J. G., Chappell, M. A., & Okell, T. W. (2019). A general framework for optimizing arterial spin labeling MRI experiments. Magnetic Resonance in Medicine, 81(4), 2474-2488. https://doi.org/10.1002/mrm.27580

Purpose
Arterial spin labeling (ASL) MRI is a non‐invasive perfusion imaging technique that is inherently SNR limited, so scan protocols ideally need to be rigorously optimized to provide the most accurate measurements. A general framework is presen... Read More about A general framework for optimizing arterial spin labeling MRI experiments.

How good is collaboration between maternity service providers in the Netherlands? (2018)
Journal Article
Cronie, D., Rijnders, M., Jans, S., Verhoeven, C. J., & de Vries, R. (2018). How good is collaboration between maternity service providers in the Netherlands?. Journal of Multidisciplinary Healthcare, 12, 21-30. https://doi.org/10.2147/jmdh.s179811

Aims: To examine the experiences of inter-professional collaboration of maternity service providers in the Netherlands and to identify potential enhancing and inhibiting factors for inter-professional collaboration within maternity care in the Nether... Read More about How good is collaboration between maternity service providers in the Netherlands?.

Demonstrably doing accountability in the internet of things (2018)
Journal Article
Urquhart, L., Lodge, T., & Crabtree, A. (2018). Demonstrably doing accountability in the internet of things. International Journal of Law and Information Technology, 27(1), 1-27. https://doi.org/10.1093/ijlit/eay015

This article explores the importance of accountability to data protection (DP), and how it can be built into the Internet of Things (IoT). The need to build accountability into the IoT is motivated by the opaque nature of distributed data flows, inad... Read More about Demonstrably doing accountability in the internet of things.

The professional development of counsellors and psychotherapists: Implications of empirical studies for supervision, training and practice (2018)
Journal Article
Rønnestad, M. H., Orlinsky, D. E., Schröder, T. A., Skovholt, T. M., & Willutzki, U. (2018). The professional development of counsellors and psychotherapists: Implications of empirical studies for supervision, training and practice. Counselling and Psychotherapy Research, 19(3), 214-230. https://doi.org/10.1002/capr.12198

Background: This article presents key findings of two major empirical studies of psychotherapist and counsellor development. Both aimed to advance knowledge of variations in professional development and better understand the complexity of formative i... Read More about The professional development of counsellors and psychotherapists: Implications of empirical studies for supervision, training and practice.

Class 1 PI3K clinical candidates and recent inhibitor design strategies: a medicinal chemistry perspective (2018)
Journal Article
Garces, A. E., & Stocks, M. J. (2019). Class 1 PI3K clinical candidates and recent inhibitor design strategies: a medicinal chemistry perspective. Journal of Medicinal Chemistry, 62(10), 4815-4850. https://doi.org/10.1021/acs.jmedchem.8b01492

Phosphatidylinositol 3-kinases (PI3Ks) are a family of lipid kinases that phosphorylate the 3-OH of the inositol ring of phosphoinositides, and deregulation of this pathway has implications in many diseases. The search for novel PI3K inhibitors has b... Read More about Class 1 PI3K clinical candidates and recent inhibitor design strategies: a medicinal chemistry perspective.

On the real catalytically active species for CO2 fixation into cyclic carbonates under near ambient conditions: dissociation equilibrium of [BMIm][Fe(NO)2Cl2] dependant on reaction temperature (2018)
Journal Article
Leu, M. K., Vicente, I., Fernandes, J. A., de Pedro, I., Dupont, J., Sans, V., …Cano, I. (2019). On the real catalytically active species for CO2 fixation into cyclic carbonates under near ambient conditions: dissociation equilibrium of [BMIm][Fe(NO)2Cl2] dependant on reaction temperature. Applied Catalysis B: Environmental, 245, 240-250. https://doi.org/10.1016/j.apcatb.2018.12.062

An imidazolium based iron-containing ionic liquid [BMIm][Fe(NO)2Cl2] (BMIm = 1-n-butyl-3-methyl-imidazolium) has been synthesized for the first time and fully characterized employing a wide range of techniques. The iron-based containing ionic liquid... Read More about On the real catalytically active species for CO2 fixation into cyclic carbonates under near ambient conditions: dissociation equilibrium of [BMIm][Fe(NO)2Cl2] dependant on reaction temperature.

The resilience paradox: flooding experience, coping and climate change mitigation intentions (2018)
Journal Article
Ogunbode, C. A., Böhm, G., Capstick, S. B., Demski, C., Spence, A., & Tausch, N. (2018). The resilience paradox: flooding experience, coping and climate change mitigation intentions. Climate Policy, 19(6), 703-715. https://doi.org/10.1080/14693062.2018.1560242

Climate change is projected to increase the frequency, intensity and unpredictability of extreme weather events across the globe and these events are likely to have significant mental health implications. The mental health literature broadly characte... Read More about The resilience paradox: flooding experience, coping and climate change mitigation intentions.

Genetic biomarkers predict response to dual BCL-2 and MCL-1 targeting in acute myeloid leukaemia cells (2018)
Journal Article
Grundy, M., Balakrishnan, S., Fox, M., Seedhouse, C., & Russell, N. (2018). Genetic biomarkers predict response to dual BCL-2 and MCL-1 targeting in acute myeloid leukaemia cells. Oncotarget, 9, Article 102. https://doi.org/10.18632/oncotarget.26540

Acute myeloid leukaemia (AML) cells often up-regulate pro-survival members of the BCL-2 protein family, such as BCL-2 and MCL-1, to avoid apoptosis. Venetoclax (ABT-199) targets BCL-2 and has shown promising efficacy in AML but over-expression of MCL... Read More about Genetic biomarkers predict response to dual BCL-2 and MCL-1 targeting in acute myeloid leukaemia cells.

Frequency difference mapping applied to the corpus callosum at 7T (2018)
Journal Article
Tendler, B. C., & Bowtell, R. (2019). Frequency difference mapping applied to the corpus callosum at 7T. Magnetic Resonance in Medicine, 81(5), 3017-3031. https://doi.org/10.1002/mrm.27626

Purpose: Frequency difference mapping (FDM) is a phase processing technique which characterises the non-linear temporal evolution of the phase of gradient echo signals. Here, a novel FDM processing algorithm is introduced, which is shown to reveal in... Read More about Frequency difference mapping applied to the corpus callosum at 7T.

Meso-scale modelling of 3D woven composite T-joints with weave variations (2018)
Journal Article
Yan, S., Zeng, X., & Long, A. (2019). Meso-scale modelling of 3D woven composite T-joints with weave variations. Composites Science and Technology, 171, 171-179. https://doi.org/10.1016/j.compscitech.2018.12.024

A meso-scale modelling framework is proposed to simulate the 3D woven fibre architectures and the mechanical performance of the composite T-joints, subjected to quasi-static tensile pull-off loading. The proposed method starts with building the reali... Read More about Meso-scale modelling of 3D woven composite T-joints with weave variations.

Enhancing Robusta coffee aroma by modifying flavour precursors in the green coffee bean (2018)
Journal Article
Liu, C., Yang, N., Yang, Q., Ayed, C., Linforth, R., & Fisk, I. D. (2019). Enhancing Robusta coffee aroma by modifying flavour precursors in the green coffee bean. Food Chemistry, 281, 8-17. https://doi.org/10.1016/j.foodchem.2018.12.080

© 2018 Elsevier Ltd This study attempted to improve Robusta sensory properties by modifying the beans chemical composition. Building on our previous work, which modified bean pH through acid pre-treatment, a model system was developed where, sugar so... Read More about Enhancing Robusta coffee aroma by modifying flavour precursors in the green coffee bean.