All Outputs (1122)

Early mortality outcomes of patients with fragility hip fracture and concurrent SARS-CoV-2 infection: a systematic review and meta-analysis (2021)
Journal Article
Alcock, H., Moppett, E., & Moppett, I. (2021). Early mortality outcomes of patients with fragility hip fracture and concurrent SARS-CoV-2 infection: a systematic review and meta-analysis. Bone & Joint Open, 2(5), 314-322. https://doi.org/10.1302/2633-1462.25.BJO-2020-0183.R1

Aims Hip fracture is a common condition of the older, frailer person. This population is also at risk from SARS-CoV-2 infection. It is important to understand the impact of coexistent hip fracture and SARS-CoV-2 for informed decision-making at patie... Read More about Early mortality outcomes of patients with fragility hip fracture and concurrent SARS-CoV-2 infection: a systematic review and meta-analysis.

Cognitive Improvement After Cochlear Implantation in Older Adults With Severe or Profound Hearing Impairment: A Prospective, Longitudinal, Controlled, Multicenter Study (2021)
Journal Article
Mertens, G., Andries, E., Claes, A. J., Topsakal, V., Van de Heyning, P., Van Rompaey, V., …Lassaletta, L. (2021). Cognitive Improvement After Cochlear Implantation in Older Adults With Severe or Profound Hearing Impairment: A Prospective, Longitudinal, Controlled, Multicenter Study. Ear and Hearing, 42(3), 606-614. https://doi.org/10.1097/AUD.0000000000000962

OBJECTIVE: To compare the cognitive evolution of older adults with severe or profound hearing impairment after cochlear implantation with that of a matched group of older adults with severe hearing impairment who do not receive a cochlear implant (CI... Read More about Cognitive Improvement After Cochlear Implantation in Older Adults With Severe or Profound Hearing Impairment: A Prospective, Longitudinal, Controlled, Multicenter Study.

A set of equations for numerically calculating the interaural level difference in the horizontal plane (2021)
Journal Article
Akeroyd, M. A., Firth, J., Graetzer, S., & Smith, S. (2021). A set of equations for numerically calculating the interaural level difference in the horizontal plane. JASA Express Letters, 1(4), Article 044402. https://doi.org/10.1121/10.0004261

The variation of interaural level difference (ILD) with direction and frequency is particularly complex and convoluted. The purpose of this work was to determine a set of parametric equations that can be used to calculate ILDs continuously at any val... Read More about A set of equations for numerically calculating the interaural level difference in the horizontal plane.

Quantitative CT radiomics-based models for prediction of haematoma expansion and poor functional outcome in primary intracerebral haemorrhage (2021)
Journal Article
Pszczolkowski, S., Manzano-Patron, J. P., Law, Z. K., Krishnan, K., Ali, A., Bath, P. M., …Dineen, R. A. (2021). Quantitative CT radiomics-based models for prediction of haematoma expansion and poor functional outcome in primary intracerebral haemorrhage. European Radiology, 31, 7945-7959. https://doi.org/10.1007/s00330-021-07826-9

Objectives To test radiomics-based features extracted from noncontrast CT of patients with spontaneous intracerebral haemorrhage for prediction of haematoma expansion and poor functional outcome and compare them with radiological signs and clinica... Read More about Quantitative CT radiomics-based models for prediction of haematoma expansion and poor functional outcome in primary intracerebral haemorrhage.

Quantitative CT radiomics-based models for prediction of haematoma expansion and poor functional outcome in primary intracerebral haemorrhage (2021)
Journal Article
Pszczolkowski, S., Manzano-Patrón, J. P., Law, Z. K., Krishnan, K., Ali, A., Bath, P. M., …Dineen, R. A. (2021). Quantitative CT radiomics-based models for prediction of haematoma expansion and poor functional outcome in primary intracerebral haemorrhage. European Radiology, 31, 7945-7959. https://doi.org/10.1007/s00330-021-07826-9

Objectives: To test radiomics-based features extracted from noncontrast CT of patients with spontaneous intracerebral haemorrhage for prediction of haematoma expansion and poor functional outcome and compare them with radiological signs and clinical... Read More about Quantitative CT radiomics-based models for prediction of haematoma expansion and poor functional outcome in primary intracerebral haemorrhage.

Accessing Voluntary HIV Testing in the Construction Industry: A Qualitative Analysis of Employee Interviews from the Test@Work Study (2021)
Journal Article
Somerset, S., Evans, C., & Blake, H. (2021). Accessing Voluntary HIV Testing in the Construction Industry: A Qualitative Analysis of Employee Interviews from the Test@Work Study. International Journal of Environmental Research and Public Health, 18(8), Article 4184. https://doi.org/10.3390/ijerph18084184

HIV, globally, remains a significant public health issue and community HIV testing can help to identify those with HIV at an early stage of disease. The workplace offers a prime location for provision of opt-in HIV testing as part of wider health pro... Read More about Accessing Voluntary HIV Testing in the Construction Industry: A Qualitative Analysis of Employee Interviews from the Test@Work Study.

The “Flying Intervention Team”: A Novel Stroke Care Concept for Rural Areas (2021)
Journal Article
Hubert, G. J., Kraus, F., Maegerlein, C., Platen, S., Friedrich, B., Kain, H., …Haberl, R. L. (2021). The “Flying Intervention Team”: A Novel Stroke Care Concept for Rural Areas. Cerebrovascular Diseases, 50(4), 375–382. https://doi.org/10.1159/000514845

Background: Endovascular treatment of large vessel occlusion in acute ischemic stroke patients is difficult to establish in remote areas, and time dependency of treatment effect increases the urge to develop health care concepts for this population.... Read More about The “Flying Intervention Team”: A Novel Stroke Care Concept for Rural Areas.

Accumulation of Brain Hypointense Foci on Susceptibility-Weighted Imaging in Childhood Ataxia Telangiectasia (2021)
Journal Article
Dineen, R. A., Blanchard, C. C., Pszczolkowski, S., Paine, S., Prasad, M., Chow, G., …Auer, D. P. (2021). Accumulation of Brain Hypointense Foci on Susceptibility-Weighted Imaging in Childhood Ataxia Telangiectasia. American Journal of Neuroradiology, 42(6), 1144-1150. https://doi.org/10.3174/ajnr.a7107

Background and Purpose Susceptibility-weighted imaging (SWI) hypointense cerebral lesions have been reported in adults with the inherited cerebellar neurodegenerative disorder ataxia telangiectasia (A-T). This study aims to establish the prevalence... Read More about Accumulation of Brain Hypointense Foci on Susceptibility-Weighted Imaging in Childhood Ataxia Telangiectasia.

Audiometric profiles and patterns of benefit: a data-driven analysis of subjective hearing difficulties and handicaps (2021)
Journal Article
Sanchez-Lopez, R., Dau, T., & Whitmer, W. M. (2022). Audiometric profiles and patterns of benefit: a data-driven analysis of subjective hearing difficulties and handicaps. International Journal of Audiology, 61(4), 301-310. https://doi.org/10.1080/14992027.2021.1905890

Objective: Hearing rehabilitation attempts to compensate for auditory dysfunction, reduce hearing difficulties and minimize participation restrictions that can lead to social isolation. However, there is no systematic approach to assess the quality o... Read More about Audiometric profiles and patterns of benefit: a data-driven analysis of subjective hearing difficulties and handicaps.

A measure of long-term hearing-aid use persistence based on battery re-ordering data (2021)
Journal Article
Zobay, O., Dillard, L. K., Naylor, G., & Saunders, G. H. (2021). A measure of long-term hearing-aid use persistence based on battery re-ordering data. Ear and Hearing, 42(5), 1441-1444. https://doi.org/10.1097/AUD.0000000000001032

Objective: We describe the construction of a hearing-aid long-term use persistence measure based on battery reorder data. The measure is derived from the notion that hearing-aid users keep using their devices for some time after placing a battery... Read More about A measure of long-term hearing-aid use persistence based on battery re-ordering data.

Burden of rare variants in synaptic genes in patients with severe tinnitus: An exome based extreme phenotype study (2021)
Journal Article
Espinosa-Sanchez, J. M., Lopez-Escamez, J. A., Cederroth, C. R., Canlon, B., May, P., Aran, I., …Gallego-Martinez, A. (2021). Burden of rare variants in synaptic genes in patients with severe tinnitus: An exome based extreme phenotype study. EBioMedicine, 66, Article 103309. https://doi.org/10.1016/j.ebiom.2021.103309

Background: tinnitus is a heterogeneous condition associated with audiological and/or mental disorders. Chronic, severe tinnitus is reported in 1% of the population and it shows a relevant heritability, according to twins, adoptees and familial aggr... Read More about Burden of rare variants in synaptic genes in patients with severe tinnitus: An exome based extreme phenotype study.

Study Protocol: The Heart and Brain Study (2021)
Journal Article
Suri, S., Bulte, D., Chiesa, S. T., Ebmeier, K. P., Jezzard, P., Rieger, S. W., …Mackay, C. E. (2021). Study Protocol: The Heart and Brain Study. Frontiers in Physiology, 12, Article 643725. https://doi.org/10.3389/fphys.2021.643725

Background: It is well-established that what is good for the heart is good for the brain. Vascular factors such as hypertension, diabetes, and high cholesterol, and genetic factors such as the apolipoprotein E4 allele increase the risk of developing... Read More about Study Protocol: The Heart and Brain Study.

Tinnitus and its associations with general health, mental health and hearing loss (2021)
Book Chapter
Stegeman, I., Eikelboom, R. H., Smit, A. L., Baguley, D. M., Bucks, R. S., Stokroos, R. J., …Atlas, M. D. (2021). Tinnitus and its associations with general health, mental health and hearing loss. . Elsevier. https://doi.org/10.1016/bs.pbr.2021.01.023

Background: A deeper knowledge of tinnitus is essential in order to better manage and treat tinnitus and its effects. Most studies to date are based on small samples and/or conducted in clinical settings. In this study we assessed the associations be... Read More about Tinnitus and its associations with general health, mental health and hearing loss.

Quantitative T1 mapping using multi-slice multi-shot inversion recovery EPI (2021)
Journal Article
Sanchez Panchuelo, R. M., Mougin, O., Turner, R., & Francis, S. T. (2021). Quantitative T1 mapping using multi-slice multi-shot inversion recovery EPI. NeuroImage, 234, Article 117976. https://doi.org/10.1016/j.neuroimage.2021.117976

An efficient multi-slice inversion–recovery EPI (MS-IR-EPI) sequence for fast, high spatial resolution, quantitative T1 mapping is presented, using a segmented simultaneous multi-slice acquisition, combined with slice order shifting across multiple a... Read More about Quantitative T1 mapping using multi-slice multi-shot inversion recovery EPI.

Determining the effects of transcranial direct current stimulation on tinnitus and tinnitus-related outcomes: protocol for a systematic review (2021)
Journal Article
Labree, B., Hoare, D. J., Gascoyne, L. E., & Sereda, M. (2021). Determining the effects of transcranial direct current stimulation on tinnitus and tinnitus-related outcomes: protocol for a systematic review. BMJ Open, 11(3), 1-6. https://doi.org/10.1136/bmjopen-2020-047191

Introduction: Tinnitus is the awareness of a sound in the ear or head in the absence of an external source. It affects around 10%–15% of people. About 20% of people with tinnitus also experience symptoms such as depression or anxiety that negatively... Read More about Determining the effects of transcranial direct current stimulation on tinnitus and tinnitus-related outcomes: protocol for a systematic review.

Systematic review of outcome domains and instruments used in designs of clinical trials for interventions that seek to restore bilateral and binaural hearing in adults with unilateral severe to profound sensorineural hearing loss (‘single-sided deafness’) (2021)
Journal Article
Katiri, R., Hall, D. A., Killan, C. F., Smith, S., Prayuenyong, P., & Kitterick, P. T. (2021). Systematic review of outcome domains and instruments used in designs of clinical trials for interventions that seek to restore bilateral and binaural hearing in adults with unilateral severe to profound sensorineural hearing loss (‘single-sided deafness’). Trials, 22, Article 220. https://doi.org/10.1186/s13063-021-05160-5

Background: This systematic review aimed to identify, compare and contrast outcome domains and outcome instruments reported in studies investigating interventions that seek to restore bilateral (two-sided) and/or binaural (both ears) hearing in adult... Read More about Systematic review of outcome domains and instruments used in designs of clinical trials for interventions that seek to restore bilateral and binaural hearing in adults with unilateral severe to profound sensorineural hearing loss (‘single-sided deafness’).

Evidence for biological markers of tinnitus: A systematic review (2021)
Book Chapter
Haider, H. F., Hoare, D. J., Ribeiro, S. F., Ribeiro, D., Caria, H., Trigueiros, N., …Sereda, M. (2021). Evidence for biological markers of tinnitus: A systematic review. In Tinnitus - An Interdisciplinary Approach Towards Individualized Treatment: Towards understanding the complexity of tinnitus (345-398). Elsevier. https://doi.org/10.1016/bs.pbr.2021.01.022

Subjective tinnitus is a phantom sound heard only by the affected person and may be a symptom of various diseases. Tinnitus diagnosis and monitoring is based on subjective audiometric and psychometric methods. This review aimed to synthesize evidence... Read More about Evidence for biological markers of tinnitus: A systematic review.

Redesigning a web-based stakeholder consensus meeting about core outcomes for clinical trials: Formative feedback study (2021)
Working Paper
Katiri, R., Hall, D. A., Hoare, D. J., Fackrell, K., Horobin, A., Buggy, N., …Core Rehabilitation Outcome Set For Single-Sided Deafness (CROSSSD) Initiative, . Redesigning a web-based stakeholder consensus meeting about core outcomes for clinical trials: Formative feedback study

Background: Clinical trials that assess the benefits and harms of an intervention do so by measuring and reporting outcomes. Inconsistent selection and diversity in the choice of outcomes makes it challenging to directly compare interventions. To... Read More about Redesigning a web-based stakeholder consensus meeting about core outcomes for clinical trials: Formative feedback study.

Real-world experience of using ciclosporin-A 0.1% (Ikervis) in the management of ocular surface inflammatory diseases (2021)
Journal Article
Deshmukh, R., Ting, D. S. J., Elsahn, A., Mohammed, I., Said, D. G., & Dua, H. S. (2022). Real-world experience of using ciclosporin-A 0.1% (Ikervis) in the management of ocular surface inflammatory diseases. British Journal of Ophthalmology, 106(8), 1087-1092. https://doi.org/10.1136/bjophthalmol-2020-317907

Purpose: To report the real-world experience of using topical ciclosporin, Ikervis, in the management of ocular surface inflammatory diseases (OSIDs). Methods: This was a retrospective study of patients treated with Ikervis for OSIDs at the Queen’... Read More about Real-world experience of using ciclosporin-A 0.1% (Ikervis) in the management of ocular surface inflammatory diseases.

Ventilation strategies for front of neck airway rescue: an in silico study (2021)
Journal Article
Laviola, M., Niklas, C., Das, A., Bates, D. G., & Hardman, J. G. (2021). Ventilation strategies for front of neck airway rescue: an in silico study. British Journal of Anaesthesia, 126(6), 1226-1236. https://doi.org/10.1016/j.bja.2021.01.030

Background. During induction of general anaesthesia a “can’t intubate, can’t oxygenate” (CICO) situation can arise, leading to severe hypoxaemia. Evidence is scarce to guide ventilation strategies for small-bore front of neck airways that ensure effe... Read More about Ventilation strategies for front of neck airway rescue: an in silico study.