All Outputs (106)

A cross-sectional study of pain sensitivity, disease-activity assessment, mental health, and fibromyalgia status in rheumatoid arthritis (2015)
Journal Article
Joharatnam, N., McWilliams, D. F., Wilson, D., Wheeler, M., Pande, I., & Walsh, D. A. (2015). A cross-sectional study of pain sensitivity, disease-activity assessment, mental health, and fibromyalgia status in rheumatoid arthritis. Arthritis Research and Therapy, 17(11), https://doi.org/10.1186/s13075-015-0525-5

INTRODUCTION: Pain remains the most important problem for people with rheumatoid arthritis (RA). Active inflammatory disease contributes to pain, but pain due to non-inflammatory mechanisms can confound the assessment of disease activity. We hypothes... Read More about A cross-sectional study of pain sensitivity, disease-activity assessment, mental health, and fibromyalgia status in rheumatoid arthritis.

Structural Associations of Symptomatic Knee Osteoarthritis: Structural Associations of Symptomatic Knee OA (2014)
Journal Article
Stoppiello, L. A., Mapp, P. I., Wilson, D., Hill, R., Scammell, B. E., & Walsh, D. A. (2014). Structural Associations of Symptomatic Knee Osteoarthritis: Structural Associations of Symptomatic Knee OA. Arthritis and Rheumatology, 66(11), 3018-3027. https://doi.org/10.1002/art.38778

Objective Structural changes of osteoarthritis (OA) may occur in the absence of pain. In this study, we aimed to identify histopathologic features that are associated with symptomatic knee OA. Methods Medial tibial plateaus and synovium samp... Read More about Structural Associations of Symptomatic Knee Osteoarthritis: Structural Associations of Symptomatic Knee OA.

Mechanisms, impact and management of pain in rheumatoid arthritis (2014)
Journal Article
Walsh, D. A., & McWilliams, D. F. (2014). Mechanisms, impact and management of pain in rheumatoid arthritis. Nature Reviews Rheumatology, 10(10), 581-592. https://doi.org/10.1038/nrrheum.2014.64

© 2014 Macmillan Publishers Limited. All rights reserved. People with rheumatoid arthritis (RA) identify pain as their most important symptom, one that often persists despite optimal control of inflammatory disease. RA pain arises from multiple mecha... Read More about Mechanisms, impact and management of pain in rheumatoid arthritis.

Increased function of pronociceptive TRPV1 at the level of the joint in a rat model of osteoarthritis pain (2013)
Journal Article
Kelly, S., Chapman, R., Woodhams, S., Sagar, D. R., Turner, J., Burston, J., …Chapman, V. (2014). Increased function of pronociceptive TRPV1 at the level of the joint in a rat model of osteoarthritis pain. Annals of the Rheumatic Diseases, 74, https://doi.org/10.1136/annrheumdis-2013-203413

Objectives Blockade of transient receptor potential vanilloid 1 (TRPV1) with systemic antagonists attenuates osteoarthritis (OA) pain behaviour in rat models, but on-target-mediated hyperthermia has halted clinical trials. The present study investiga... Read More about Increased function of pronociceptive TRPV1 at the level of the joint in a rat model of osteoarthritis pain.

Augmented pain behavioural responses to intra-articular injection of nerve growth factor in two animal models of osteoarthritis (2013)
Journal Article
Ashraf, S., Mapp, P. I., Chapman, V., Burston, J., Bennett, A., & Walsh, D. A. (2014). Augmented pain behavioural responses to intra-articular injection of nerve growth factor in two animal models of osteoarthritis. Annals of the Rheumatic Diseases, 73(9), 1710-1718. https://doi.org/10.1136/annrheumdis-2013-203416

The experience of living with knee osteoarthritis: exploring illness and treatment beliefs through thematic analysis (2013)
Journal Article
Pouli, N., das Nair, R., Lincoln, N., & Walsh, D. A. (2013). The experience of living with knee osteoarthritis: exploring illness and treatment beliefs through thematic analysis. Disability and Rehabilitation, 36(7), https://doi.org/10.3109/09638288.2013.805257

Purpose: Knee osteoarthritis (OA) is a major cause of disability in older adults. However, there is limited research on the daily experience of living with knee OA. We aimed to offer insight into the beliefs of patients with knee OA about their illne... Read More about The experience of living with knee osteoarthritis: exploring illness and treatment beliefs through thematic analysis.