Cytoplasmic Cyclin E Predicts Recurrence in Patients with Breast Cancer
(2016)
Journal Article
Hunt, K. K., Karakas, C., Ha, M. J., Biernacka, A., Yi, M., Sahin, A., …Keyomarsi, K. (2017). Cytoplasmic Cyclin E Predicts Recurrence in Patients with Breast Cancer. Clinical Cancer Research, 23(12), 2991-3002. https://doi.org/10.1158/1078-0432.ccr-16-2217
Background: Low-molecular-weight-cyclin E (LMW-E) detected by Western blot, predicts for reduced breast cancer survival, however, it is impractical for clinical use. LMW-E lacks a nuclear localization signal which leads to accumulation in the cytopla... Read More about Cytoplasmic Cyclin E Predicts Recurrence in Patients with Breast Cancer.