Childhood environment influences epigenetic age and methylation concordance of a CpG clock locus in British-Bangladeshi migrants

Stöger, Reinhard; Choi, Minseung; Begum, Khurshida; Leeman, Gregory; Emes, Richard D.; Melamed, Philippa; Bentley, Gillian R.

doi:10.1080/15592294.2022.2153511

All Outputs (3376)

On the maximum dual volume of a canonical Fano polytope (2022)
Journal Article
Balletti, G., Kasprzyk, A. M., & Nill, B. (2022). On the maximum dual volume of a canonical Fano polytope. Forum of Mathematics, Sigma, 10, Article e109. https://doi.org/10.1017/fms.2022.93

We give an upper bound on the volume vol(P*) of a polytope P* dual to a d-dimensional lattice polytope P with exactly one interior lattice point, in each dimension d. This bound, expressed in terms of the Sylvester sequence, is sharp, and is achieved... Read More about On the maximum dual volume of a canonical Fano polytope.

Interventions for the eradication of meticillin-resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis (2022)
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Smyth, A. R., Lo, D. K., & Muhlebach, M. S. (2022). Interventions for the eradication of meticillin-resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis. Cochrane Database of Systematic Reviews, 2022(12), Article CD009650. https://doi.org/10.1002/14651858.cd009650.pub5

Background Cystic fibrosis is an inherited recessive disorder of chloride transport that is characterised by recurrent and persistent pulmonary infections from resistant organisms that result in lung function deterioration and early mortality in suf... Read More about Interventions for the eradication of meticillin-resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis.

The Impact of the Media Portrayal of Coeliac Disease: A Qualitative Study (2022)
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Verma, S. R., & Bains, M. (2022). The Impact of the Media Portrayal of Coeliac Disease: A Qualitative Study. Cureus, https://doi.org/10.7759/cureus.32444

Attention and Interhemispheric Communication: Implications for Language Dominance (2022)
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Serrien, D. J., & O'Regan, L. (2023). Attention and Interhemispheric Communication: Implications for Language Dominance. Neuroscience, 510, 21-31. https://doi.org/10.1016/j.neuroscience.2022.12.006

Dominance of the left hemisphere for language processing is a prominent feature of brain organisation. Whereas structural models clarify the functional asymmetry due to direct access to local language circuits, dynamic models propose functional state... Read More about Attention and Interhemispheric Communication: Implications for Language Dominance.

Techniques for managing an impacted fetal head at caesarean section: A systematic review (2022)
Journal Article
Peak, A. G., Barwise, E., & Walker, K. F. (2023). Techniques for managing an impacted fetal head at caesarean section: A systematic review. European Journal of Obstetrics and Gynecology and Reproductive Biology, 281, 12-22. https://doi.org/10.1016/j.ejogrb.2022.12.017

A complication arising at caesarean birth when the baby's head is deeply engaged in the pelvis and may be difficult to deliver, is known as an ‘impacted fetal head’. This obstetric emergency occurs in 16% of second stage caesarean sections. Multiple... Read More about Techniques for managing an impacted fetal head at caesarean section: A systematic review.

A theoretical framework underlying an accelerated testing method and its application to composites under constant strain rates and fatigue loading (2022)
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Xu, F., Arthur Jones, I., & Li, S. (2022). A theoretical framework underlying an accelerated testing method and its application to composites under constant strain rates and fatigue loading. Science and Engineering of Composite Materials, 29(1), 488-499. https://doi.org/10.1515/secm-2022-0012

A theoretical framework that underlies an accelerated testing method for unidirectional (UD) composites is proposed in this article, based on the continuum damage mechanics and time-temperature superposition. By the way of demonstration, it has been... Read More about A theoretical framework underlying an accelerated testing method and its application to composites under constant strain rates and fatigue loading.

Double diaphragm forming simulation for net-shape component using multi-layered biaxial non-crimp fabrics (2022)
Journal Article
Yu, F., Chen, X., & Chen, S. (2022). Double diaphragm forming simulation for net-shape component using multi-layered biaxial non-crimp fabrics. Journal of Physics: Conference Series, 2383(1), Article 012129. https://doi.org/10.1088/1742-6596/2383/1/012129

Compared to autoclave-cured prepreg, liquid composite moulding (LCM) is a cost-effective alternative to produce advanced composites, thanks to the less-expensive intermediate materials, lower capital investment and shorter cycle time. A separate pref... Read More about Double diaphragm forming simulation for net-shape component using multi-layered biaxial non-crimp fabrics.

Crop improvements for future‐proofing European food systems: A focus‐group‐driven analysis of agricultural production stakeholder priorities and viewpoints (2022)
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Stetkiewicz, S., Menary, J., Nair, A., Rufino, M. C., Fischer, A. R., Cornelissen, M., …Davies, J. A. (2022). Crop improvements for future‐proofing European food systems: A focus‐group‐driven analysis of agricultural production stakeholder priorities and viewpoints. Food and Energy Security, Article e362. https://doi.org/10.1002/fes3.362

Crop breeding is one of the main tools which can assist in future-proofing food systems for more sustainable outcomes. In order to ensure priorities are aligned with the needs and wants of food system actors, it is essential to engage with key stakeh... Read More about Crop improvements for future‐proofing European food systems: A focus‐group‐driven analysis of agricultural production stakeholder priorities and viewpoints.

meta-Selective C–H arylation of phenols via regiodiversion of electrophilic aromatic substitution (2022)
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Senior, A., Ruffell, K., & Ball, L. T. (2022). meta-Selective C–H arylation of phenols via regiodiversion of electrophilic aromatic substitution. Nature Chemistry, https://doi.org/10.1038/s41557-022-01101-0

Electrophilic aromatic substitution is among the most widely used mechanistic manifolds in organic chemistry. Access to certain substitution patterns is, however, precluded by intrinsic and immutable substituent effects that ultimately restrict the d... Read More about meta-Selective C–H arylation of phenols via regiodiversion of electrophilic aromatic substitution.

A continuum framework for phase field with bulk-surface dynamics (2022)
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Espath, L. (2023). A continuum framework for phase field with bulk-surface dynamics. Partial Differential Equations and Applications, 4, Article 1. https://doi.org/10.1007/s42985-022-00218-8

This continuum mechanical theory aims at detailing the underlying rational mechanics of dynamic boundary conditions proposed by Fischer et al. (Phys Rev Lett 79:893, 1997), Goldstein et al. (Phys D Nonlinear Phenom 240:754–766, 2011), and Knopf et al... Read More about A continuum framework for phase field with bulk-surface dynamics.

Online Parent Training for The Initial Management of ADHD referrals (OPTIMA): the protocol for a randomised controlled trial of a digital parenting intervention implemented to support parents and children on a treatment waitlist (2022)
Journal Article
Kostyrka-Allchorne, K., Ballard, C., Byford, S., Cortese, S., Daley, D., Downs, J., …Sonuga-Barke, E. J. S. (2022). Online Parent Training for The Initial Management of ADHD referrals (OPTIMA): the protocol for a randomised controlled trial of a digital parenting intervention implemented to support parents and children on a treatment waitlist. Trials, 23(1), Article 1003. https://doi.org/10.1186/s13063-022-06952-z

Background: Children referred for attention-deficit/hyperactivity disorder (ADHD) often present with a broader pattern of conduct problems including oppositionality and defiance. This combination can be extremely stressful to parents, lower parents’... Read More about Online Parent Training for The Initial Management of ADHD referrals (OPTIMA): the protocol for a randomised controlled trial of a digital parenting intervention implemented to support parents and children on a treatment waitlist.

No evidence for persistent natural plague reservoirs in historical and modern Europe (2022)
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Stenseth, N. C., Tao, Y., Zhang, C., Bramanti, B., Büntgen, U., Cong, X., …Xu, L. (2022). No evidence for persistent natural plague reservoirs in historical and modern Europe. Proceedings of the National Academy of Sciences, 119(51), Article e2209816119. https://doi.org/10.1073/pnas.2209816119

Caused by Yersinia pestis, plague ravaged the world through three known pandemics: the First or the Justinianic (6th–8th century); the Second (beginning with the Black Death during c.1338–1353 and lasting until the 19th century); and the Third (which... Read More about No evidence for persistent natural plague reservoirs in historical and modern Europe.

Microporous metallic scaffolds supported liquid infused icephobic construction (2022)
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Wu, M., Wang, J., Ling, S., Wheatley, R., & Hou, X. (2023). Microporous metallic scaffolds supported liquid infused icephobic construction. Journal of Colloid and Interface Science, 634, 369-378. https://doi.org/10.1016/j.jcis.2022.12.034

Hypothesis: Ice accretion on component surfaces often causes severe impacts or accidents. Liquid-infused surfaces (LIS) have drawn much attention as icephobic materials for ice mitigation in recent years due to their outstanding icephobicity. However... Read More about Microporous metallic scaffolds supported liquid infused icephobic construction.

Italian guidelines for the management of irritable bowel syndrome: Joint Consensus from the Italian Societies of: Gastroenterology and Endoscopy (SIGE), Neurogastroenterology and Motility (SINGEM), Hospital Gastroenterologists and Endoscopists (AIGO), Digestive Endoscopy (SIED), General Medicine (SIMG), Gastroenterology, Hepatology and Pediatric Nutrition (SIGENP) and Pediatrics (SIP) (2022)
Journal Article
Barbara, G., Cremon, C., Bellini, M., Corsetti, M., Di Nardo, G., Falangone, F., …Marasco, G. (2023). Italian guidelines for the management of irritable bowel syndrome: Joint Consensus from the Italian Societies of: Gastroenterology and Endoscopy (SIGE), Neurogastroenterology and Motility (SINGEM), Hospital Gastroenterologists and Endoscopists (AIGO), Digestive Endoscopy (SIED), General Medicine (SIMG), Gastroenterology, Hepatology and Pediatric Nutrition (SIGENP) and Pediatrics (SIP). Digestive and Liver Disease, 55(2), 187-207. https://doi.org/10.1016/j.dld.2022.11.015

The irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interaction. IBS is still associated with areas of uncertainties, especially regarding the optimal diagnostic work-up and the more appropriate management. Experts from 7 Italian So... Read More about Italian guidelines for the management of irritable bowel syndrome: Joint Consensus from the Italian Societies of: Gastroenterology and Endoscopy (SIGE), Neurogastroenterology and Motility (SINGEM), Hospital Gastroenterologists and Endoscopists (AIGO), Digestive Endoscopy (SIED), General Medicine (SIMG), Gastroenterology, Hepatology and Pediatric Nutrition (SIGENP) and Pediatrics (SIP).

Italian guidelines for the management of irritable bowel syndrome: Joint Consensus from the Italian Societies of: Gastroenterology and Endoscopy (SIGE), Neurogastroenterology and Motility (SINGEM), Hospital Gastroenterologists and Endoscopists (AIGO), Digestive Endoscopy (SIED), General Medicine (SIMG), Gastroenterology, Hepatology and Pediatric Nutrition (SIGENP) and Pediatrics (SIP) (2022)
Journal Article
Barbara, G., Cremon, C., Bellini, M., Corsetti, M., Di Nardo, G., Falangone, F., …Marasco, G. (2022). Italian guidelines for the management of irritable bowel syndrome: Joint Consensus from the Italian Societies of: Gastroenterology and Endoscopy (SIGE), Neurogastroenterology and Motility (SINGEM), Hospital Gastroenterologists and Endoscopists (AIGO), Digestive Endoscopy (SIED), General Medicine (SIMG), Gastroenterology, Hepatology and Pediatric Nutrition (SIGENP) and Pediatrics (SIP). Digestive and Liver Disease, https://doi.org/10.1016/j.dld.2022.11.015

The irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interaction. IBS is still associated with areas of uncertainties, especially regarding the optimal diagnostic work-up and the more appropriate management. Experts from 7 Italian So... Read More about Italian guidelines for the management of irritable bowel syndrome: Joint Consensus from the Italian Societies of: Gastroenterology and Endoscopy (SIGE), Neurogastroenterology and Motility (SINGEM), Hospital Gastroenterologists and Endoscopists (AIGO), Digestive Endoscopy (SIED), General Medicine (SIMG), Gastroenterology, Hepatology and Pediatric Nutrition (SIGENP) and Pediatrics (SIP).

Kinetic analysis of endogenous β2-adrenoceptor-mediated cAMP GloSensorTM responses in HEK293 cells (2022)
Journal Article
Cullum, S. A., Veprintsev, D. B., & Hill, S. J. (2023). Kinetic analysis of endogenous β2-adrenoceptor-mediated cAMP GloSensorTM responses in HEK293 cells. British Journal of Pharmacology, 180(10), 1304-1315. https://doi.org/10.1111/bph.16008

Background and Aim: Standard pharmacological analysis of agonist activity utilises measurements of receptor-mediated responses at a set time-point, or at the peak response level, to characterise ligands. However, the occurrence of non-equilibrium con... Read More about Kinetic analysis of endogenous β2-adrenoceptor-mediated cAMP GloSensorTM responses in HEK293 cells.

Raising the Research Octane Number using an optimized Simulated Moving Bed technology towards greater sustainability and economic return (2022)
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Muhammed, T., Tokay, B., & Conradie, A. (2023). Raising the Research Octane Number using an optimized Simulated Moving Bed technology towards greater sustainability and economic return. Fuel, Article 126864. https://doi.org/10.1016/j.fuel.2022.126864

The scale of CO2 emissions from light-duty vehicle (LDV) fleets worldwide has led governments to mandate substantive improvements in vehicle fuel economy, thereby mitigating climate change. Raising the Research Octane Number (RON) of fuel through iso... Read More about Raising the Research Octane Number using an optimized Simulated Moving Bed technology towards greater sustainability and economic return.

One size does not fit all: Impact of hand size on ease of use of instruments for minimally invasive surgery (2022)
Journal Article
Green, S. V., Morris, D. E., Naumann, D. N., Rhodes, H. L., Burns, J. K., Roberts, R., …Morris, L. (2023). One size does not fit all: Impact of hand size on ease of use of instruments for minimally invasive surgery. The Surgeon, 21(5), 267-272. https://doi.org/10.1016/j.surge.2022.11.001

Background: Consideration of ergonomic factors is important for the practice of safe and efficient minimally invasive surgery (MIS). Surgeons with smaller glove sizes have previously been reported to have increased difficulties with some minimally in... Read More about One size does not fit all: Impact of hand size on ease of use of instruments for minimally invasive surgery.

Beyond the Beta Rebound: Post-Task Responses in Oscillatory Activity follow Cessation of Working Memory Processes (2022)
Journal Article
Coleman, S. C., Seedat, Z. A., Whittaker, A. C., Lenartowicz, A., & Mullinger, K. J. (2023). Beyond the Beta Rebound: Post-Task Responses in Oscillatory Activity follow Cessation of Working Memory Processes. NeuroImage, 265, Article 119801. https://doi.org/10.1016/j.neuroimage.2022.119801

Post-task responses (PTRs) are transitionary responses occurring for several seconds between the end of a stimulus/task and a period of rest. The most well-studied of these are beta band (13 – 30 Hz) PTRs in motor networks following movement, often c... Read More about Beyond the Beta Rebound: Post-Task Responses in Oscillatory Activity follow Cessation of Working Memory Processes.

Childhood environment influences epigenetic age and methylation concordance of a CpG clock locus in British-Bangladeshi migrants (2022)
Journal Article
Stöger, R., Choi, M., Begum, K., Leeman, G., Emes, R. D., Melamed, P., & Bentley, G. R. (2023). Childhood environment influences epigenetic age and methylation concordance of a CpG clock locus in British-Bangladeshi migrants. Epigenetics, 18(1), Article 2153511. https://doi.org/10.1080/15592294.2022.2153511

Migration from one location to another often comes with a change in environmental conditions. Here, we analysed features of DNA methylation in young, adult British-Bangladeshi women who experienced different environments during their childhoods: a) m... Read More about Childhood environment influences epigenetic age and methylation concordance of a CpG clock locus in British-Bangladeshi migrants.