All Outputs (4)

Human adaptation to immobilization: Novel insights of impacts on glucose disposal and fuel utilization (2022)
Journal Article
Shur, N. F., Simpson, E. J., Crossland, H., Chivaka, P. K., Constantin, D., Cordon, S. M., …Greenhaff, P. L. (2022). Human adaptation to immobilization: Novel insights of impacts on glucose disposal and fuel utilization. Journal of Cachexia, Sarcopenia and Muscle, 13(6), 2999-3013. https://doi.org/10.1002/jcsm.13075

Background: Bed rest (BR) reduces whole-body insulin-stimulated glucose disposal (GD) and alters muscle fuel metabolism, but little is known about metabolic adaptation from acute to chronic BR nor the mechanisms involved, particularly when volunteers... Read More about Human adaptation to immobilization: Novel insights of impacts on glucose disposal and fuel utilization.

Does the Effect of a 3-Year Lifestyle Intervention on Body Weight and Cardiometabolic Health Differ by Prediabetes Metabolic Phenotype? A Post Hoc Analysis of the PREVIEW Study (2022)
Journal Article
Zhu, R., Jalo, E., Silvestre, M. P., Poppitt, S. D., Handjieva-Darlenska, T., Handjiev, S., …Raben, A. (2022). Does the Effect of a 3-Year Lifestyle Intervention on Body Weight and Cardiometabolic Health Differ by Prediabetes Metabolic Phenotype? A Post Hoc Analysis of the PREVIEW Study. Diabetes Care, 45(11), 2698-2708. https://doi.org/10.2337/dc22-0549

OBJECTIVE: To examine whether the effect of a 3-year lifestyle intervention on body weight and cardiometabolic risk factors differs by prediabetes metabolic phenotype. RESEARCH DESIGN AND METHODS: This post hoc analysis of the multicenter, random... Read More about Does the Effect of a 3-Year Lifestyle Intervention on Body Weight and Cardiometabolic Health Differ by Prediabetes Metabolic Phenotype? A Post Hoc Analysis of the PREVIEW Study.

Age- and sex-specific effects of a long-term lifestyle intervention on body weight and cardiometabolic health markers in adults with prediabetes: results from the diabetes prevention study PREVIEW (2022)
Journal Article
Zhu, R., Craciun, I., Bernhards-Werge, J., Jalo, E., Poppitt, S. D., Silvestre, M. P., …Raben, A. (2022). Age- and sex-specific effects of a long-term lifestyle intervention on body weight and cardiometabolic health markers in adults with prediabetes: results from the diabetes prevention study PREVIEW. Diabetologia, 65(8), 1262-1277. https://doi.org/10.1007/s00125-022-05716-3

Aims/hypothesis Lifestyle interventions are the first-line treatment option for body weight and cardiometabolic health management. However, whether age groups or women and men respond differently to lifestyle interventions is under debate. We aime... Read More about Age- and sex-specific effects of a long-term lifestyle intervention on body weight and cardiometabolic health markers in adults with prediabetes: results from the diabetes prevention study PREVIEW.

Energy Intake of Men With Excess Weight During Normobaric Hypoxic Confinement (2022)
Journal Article
Mekjavic, I. B., Amon, M., Simpson, E. J., Kölegård, R., Eiken, O., & Macdonald, I. A. (2022). Energy Intake of Men With Excess Weight During Normobaric Hypoxic Confinement. Frontiers in Physiology, 12, Article 801833. https://doi.org/10.3389/fphys.2021.801833

Due to the observations of weight loss at high altitude, normobaric hypoxia has been considered as a method of weight loss in obese individuals. With this regard, the aim of the present study was to determine the effect of hypoxia per se on metabolis... Read More about Energy Intake of Men With Excess Weight During Normobaric Hypoxic Confinement.