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Inverse association between blood pressure and pulse oximetry accuracy: an observational study in patients with suspected or confirmed COVID-19 infection (2022)
Journal Article
Crooks, C. J., West, J., Morling, J., Simmonds, M., Juurlink, I., Briggs, S., …Fogarty, A. W. (2023). Inverse association between blood pressure and pulse oximetry accuracy: an observational study in patients with suspected or confirmed COVID-19 infection. Emergency Medicine Journal, 40(3), 216-220. https://doi.org/10.1136/emermed-2022-212443

Background Pulse oximeters are a standard non-invasive tool to measure blood oxygen levels, and are used in multiple healthcare settings. It is important to understand the factors affecting their accuracy to be able to use them optimally and safely.... Read More about Inverse association between blood pressure and pulse oximetry accuracy: an observational study in patients with suspected or confirmed COVID-19 infection.

Risk of Suicide After Dementia Diagnosis (2022)
Journal Article
Alothman, D., Card, T., Lewis, S., Tyrrell, E., Fogarty, A. W., & Marshall, C. R. (2022). Risk of Suicide After Dementia Diagnosis. JAMA Neurology, 79(11), 1148-1154. https://doi.org/10.1001/jamaneurol.2022.3094

Importance: Patients with dementia may be at an increased suicide risk. Identifying groups at greatest risk of suicide would support targeted risk reduction efforts by clinical dementia services. Objectives: To examine the association between a d... Read More about Risk of Suicide After Dementia Diagnosis.

Differential pulse oximetry readings between ethnic groups and delayed transfer to intensive care units (2022)
Journal Article
Crooks, C. J., West, J., Morling, J. R., Simmonds, M., Juurlink, I., Briggs, S., …Fogarty, A. W. (2023). Differential pulse oximetry readings between ethnic groups and delayed transfer to intensive care units. QJM: An International Journal of Medicine, 116(1), 63-67. https://doi.org/10.1093/qjmed/hcac218

Summary Background Pulse oximeters are widely used to monitor blood oxygen saturations, although concerns exist that they are less accurate in individuals with pigmented skin. Aims This study aimed to determine if patients with pigmented skin were mo... Read More about Differential pulse oximetry readings between ethnic groups and delayed transfer to intensive care units.

Predicting Need for Escalation of Care or Death From Repeated Daily Clinical Observations and Laboratory Results in Patients With Severe Acute Respiratory Syndrome Coronavirus 2 (2022)
Journal Article
Crooks, C. J., West, J., Fogarty, A., Morling, J. R., Grainge, M. J., Gonem, S., …Card, T. R. (2022). Predicting Need for Escalation of Care or Death From Repeated Daily Clinical Observations and Laboratory Results in Patients With Severe Acute Respiratory Syndrome Coronavirus 2. American Journal of Epidemiology, 191(11), 1944-1953. https://doi.org/10.1093/aje/kwac126

We compared the performance of prognostic tools for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using parameters fitted either at the time of hospital admission or across all time points of an admission. This cohort study used clinic... Read More about Predicting Need for Escalation of Care or Death From Repeated Daily Clinical Observations and Laboratory Results in Patients With Severe Acute Respiratory Syndrome Coronavirus 2.

Age modifies both the maximal temperature and inflammatory response in patients with SARS-CoV-2 infection (2022)
Journal Article
Crooks, C. J., West, J., Morling, J. R., Simmonds, M., Juurlink, I., Briggs, S., …Fogarty, A. (2022). Age modifies both the maximal temperature and inflammatory response in patients with SARS-CoV-2 infection. Clinical Medicine, 22(3), 192-196. https://doi.org/10.7861/clinmed.2021-0603

Objective To determine the maximal response of the temperature and inflammatory response to SARS-CoV-2 infection and how these are modified by age. Methods Participants were patients admitted to hospital with SARS-CoV-2 infection. For each partici... Read More about Age modifies both the maximal temperature and inflammatory response in patients with SARS-CoV-2 infection.

Silent hypoxia is not an identifiable characteristic in patients with COVID-19 infection (2022)
Journal Article
Plummer, N. R., Fogarty, A., Shaw, D., Card, T., West, J., & Crooks, C. (2022). Silent hypoxia is not an identifiable characteristic in patients with COVID-19 infection. Respiratory Medicine, 197, Article 106858. https://doi.org/10.1016/j.rmed.2022.106858

Background: We aimed to assess whether asymptomatic (“happy”) hypoxia was an identifiable physiological phenotype of COVID-19 acute respiratory distress syndrome (ARDS), and associated with need for ICU admission. Methods: We performed an observation... Read More about Silent hypoxia is not an identifiable characteristic in patients with COVID-19 infection.

Risk of mortality from suicide in patients with Huntington’s disease is increased compared to the general population in England (2022)
Journal Article
Alothman, D., Marshall, C. R., Tyrrell, E., Lewis, S., Card, T., & Fogarty, A. (2022). Risk of mortality from suicide in patients with Huntington’s disease is increased compared to the general population in England. Journal of Neurology, 269, 4436–4439. https://doi.org/10.1007/s00415-022-11085-z

Objective: To examine the relative risk of suicide mortality in patients with Huntington’s disease (HD). Methods: A case–control study design was used. We used linked electronic records from primary care, secondary care and Office for National Statis... Read More about Risk of mortality from suicide in patients with Huntington’s disease is increased compared to the general population in England.

Potential Risk Factors of Smokeless Tobacco Consumption Among Adolescents in South India (2022)
Journal Article
Kulkarni, M. M., Kamath, V. G., Kamath, A., Lewis, S., Bogdanovica, I., Bains, M., …Britton, J. (2022). Potential Risk Factors of Smokeless Tobacco Consumption Among Adolescents in South India. Nicotine and Tobacco Research, 24(7), 1104-1109. https://doi.org/10.1093/ntr/ntac003

Introduction: Although most of the disease burden is due to tobacco smoking, smokeless tobacco (SLT) use contributed to an estimated 76,000 deaths in 2017. We have studied the potential risk factors for SLT use among adolescents in South India. M... Read More about Potential Risk Factors of Smokeless Tobacco Consumption Among Adolescents in South India.

The high frequency of alcohol advertising during televised English Premier League football games shown in Ethiopia (2022)
Journal Article
Tamire, M., Barker, A., Getachew, S., Murray, R. L., Amedala, R., Britton, J., …Fogarty, A. W. (2022). The high frequency of alcohol advertising during televised English Premier League football games shown in Ethiopia. Harm Reduction Journal, 19, Article 11. https://doi.org/10.1186/s12954-022-00591-y

Background: Excessive alcohol consumption is an important risk factor for increased morbidity, mortality and other social harms globally. Televised sport allows the promotion of alcoholic drinks to a large and often young audience, and thus can be us... Read More about The high frequency of alcohol advertising during televised English Premier League football games shown in Ethiopia.

Porphyromonas pasteri and Prevotella nanceiensis in the sputum microbiota are associated with increased decline in lung function in individuals with cystic fibrosis (2022)
Journal Article
Webb, K., Zain, N. M. M., Stewart, I., Fogarty, A., Nash, E. F., Whitehouse, J. L., …Barr, H. L. (2022). Porphyromonas pasteri and Prevotella nanceiensis in the sputum microbiota are associated with increased decline in lung function in individuals with cystic fibrosis. Journal of Medical Microbiology, 71(2), Article 001481. https://doi.org/10.1099/jmm.0.001481

Although anaerobic bacteria exist in abundance in cystic fibrosis (CF) airways, their role in disease progression is poorly understood. We hypothesized that the presence and relative abundance of the most prevalent, live, anaerobic bacteria in sputum... Read More about Porphyromonas pasteri and Prevotella nanceiensis in the sputum microbiota are associated with increased decline in lung function in individuals with cystic fibrosis.