All Outputs (6)

UK Multicenter Prospective Evaluation of the Leibovich Score in Localized Renal Cell Carcinoma: Performance has Altered Over Time (2019)
Journal Article
Vasudev, N. S., Hutchinson, M., Trainor, S., Ferguson, R., Bhattarai, S., Adeyoju, A., …Banks, R. E. (2019). UK Multicenter Prospective Evaluation of the Leibovich Score in Localized Renal Cell Carcinoma: Performance has Altered Over Time. Urology, https://doi.org/10.1016/j.urology.2019.09.044

© 2019 The Authors Objective: To examine changes in outcome by the Leibovich score using contemporary and historic cohorts of patients presenting with renal cell carcinoma (RCC) Patients and Methods: Prospective observational multicenter cohort study... Read More about UK Multicenter Prospective Evaluation of the Leibovich Score in Localized Renal Cell Carcinoma: Performance has Altered Over Time.

Cancer survivors treated with platinum-based chemotherapy affected by ototoxicity and the impact on quality of life: a narrative synthesis systematic review (2019)
Journal Article
Pearson, S. E., Taylor, J., Patel, P., & Baguley, D. M. (2019). Cancer survivors treated with platinum-based chemotherapy affected by ototoxicity and the impact on quality of life: a narrative synthesis systematic review. International Journal of Audiology, 58(11), 685-695. https://doi.org/10.1080/14992027.2019.1660918

© 2019, © 2019 British Society of Audiology, International Society of Audiology, and Nordic Audiological Society. Objective: To identify any change in quality of life (QoL) caused by chemotherapy-induced toxicities, such as hearing loss and tinnitus,... Read More about Cancer survivors treated with platinum-based chemotherapy affected by ototoxicity and the impact on quality of life: a narrative synthesis systematic review.

Meta-Analysis in Metastatic Uveal Melanoma to Determine Progression-Free and Overall Survival Benchmarks: an International Rare Cancers Initiative (IRCI) Ocular Melanoma study (2019)
Journal Article
Khoja, L., Atenafu, E., Suciu, S., Leyvraz, S., Sato, T., Marshall, E., …Joshua, A. (2019). Meta-Analysis in Metastatic Uveal Melanoma to Determine Progression-Free and Overall Survival Benchmarks: an International Rare Cancers Initiative (IRCI) Ocular Melanoma study. Annals of Oncology, 30(8), 1370-1380. https://doi.org/10.1093/annonc/mdz176

Background: Despite the completion of numerous phase II studies, a standard of care treatment has yet to be defined for metastatic uveal melanoma (mUM). To determine benchmarks of progression free survival (PFS) and overall survival (OS), we carried... Read More about Meta-Analysis in Metastatic Uveal Melanoma to Determine Progression-Free and Overall Survival Benchmarks: an International Rare Cancers Initiative (IRCI) Ocular Melanoma study.

Impaired circulating myeloid CD1c+ dendritic cell function in human glioblastoma is restored by p38 inhibition - implications for the next generation of DC vaccines (2019)
Journal Article
Adhikaree, J., Franks, H. A., Televantos, C., Vaghela, P., Kaur, A. P., Walker, D., …Patel, P. M. (2019). Impaired circulating myeloid CD1c+ dendritic cell function in human glioblastoma is restored by p38 inhibition - implications for the next generation of DC vaccines. OncoImmunology, 8(7), 1-12. https://doi.org/10.1080/2162402X.2019.1593803

Current treatments for glioblastoma (GBM) have limited efficacy and significant morbidity and therefore new strategies are urgently needed. Dendritic cells have the power to create anti-tumour immune responses. The greater potency of circulating den... Read More about Impaired circulating myeloid CD1c+ dendritic cell function in human glioblastoma is restored by p38 inhibition - implications for the next generation of DC vaccines.

Exploring the experiences of cancer patients with chemotherapy induced ototoxicity: qualitative study using online health forums (2019)
Journal Article
Pearson, S. E., Taylor, J. A., Hoare, D. J., Patel, P., & Baguley, D. M. (2019). Exploring the experiences of cancer patients with chemotherapy induced ototoxicity: qualitative study using online health forums. JMIR Cancer, 5(1), https://doi.org/10.2196/10883

Background: Many cancer patients and survivors experience permanent and life-debilitating effects, such as ototoxicity, from treatment. Ototoxicity manifests as high-frequency hearing loss and tinnitus, which can have a detrimental effect on the qual... Read More about Exploring the experiences of cancer patients with chemotherapy induced ototoxicity: qualitative study using online health forums.

The genetic vulnerability to cisplatin ototoxicity: a systematic review (2019)
Journal Article
Edvall, N. K., Cederroth, C. R., Tserga, E., Nandwani, T., Edvall, N. K., Bulla, J., …Baguley, D. M. (2019). The genetic vulnerability to cisplatin ototoxicity: a systematic review. Scientific Reports, 9, Article 3455. https://doi.org/10.1038/s41598-019-40138-z

Ototoxicity is one of the major side-effects of platinum-based chemotherapy, in particular cisplatin (cis-diammine dichloroplatinum II). To our knowledge, no systematic review has previously provided a quantitative summary estimate of the impact of g... Read More about The genetic vulnerability to cisplatin ototoxicity: a systematic review.