Association Between Oxygen Saturation Targeting and Death or Disability in Extremely Preterm Infants in the Neonatal Oxygenation Prospective Meta-analysis Collaboration

Askie, Lisa M.; Darlow, Brian A.; Finer, Neil; Schmidt, Barbara; Stenson, Ben; Tarnow-Mordi, William; Davis, Peter G.; Carlo, Waldemar A.; Brocklehurst, Peter; Davies, Lucy C.; Das, Abhik; Rich, Wade; Gantz, Marie G.; Roberts, Robin S.; Whyte, Robin K.; Costantini, Lorrie; Poets, Christian; Asztalos, Elizabeth; Battin, Malcolm; Halliday, Henry L.; Marlow, Neil; Tin, Win; King, Andrew; Juszczak, Edmund; Morley, Colin J.; Doyle, Lex W.; Gebski, Val; Hunter, Kylie E.; Simes, Robert J.; for the Neonatal Oxygenation Prospective Meta-analysis (NeOProM) Collaboration

doi:10.1001/jama.2018.5725

All Outputs (4)

Enteral lactoferrin to prevent infection for very preterm infants: the ELFIN RCT (2018)
Journal Article
Griffiths, J., Jenkins, P., Vargova, M., Bowler, U., Juszczak, E., King, A., …Oddie, S. (2018). Enteral lactoferrin to prevent infection for very preterm infants: the ELFIN RCT. Health Technology Assessment, 22(74), 1-60. https://doi.org/10.3310/hta22740

Analgesic efficacy and safety of morphine in the Procedural Pain in Premature Infants (Poppi) study: randomised placebo-controlled trial (2018)
Journal Article
Hartley, C., Moultrie, F., Hoskin, A., Green, G., Monk, V., Bell, J. L., …Slater, R. (2018). Analgesic efficacy and safety of morphine in the Procedural Pain in Premature Infants (Poppi) study: randomised placebo-controlled trial. Lancet, 392(10164), 2595-2605. https://doi.org/10.1016/S0140-6736%2818%2931813-0

Background: Infant pain has immediate and long-term effects but is undertreated because of a paucity of evidence-based analgesics. Although morphine is often used to sedate ventilated infants, its analgesic efficacy is unclear. We aimed to establish... Read More about Analgesic efficacy and safety of morphine in the Procedural Pain in Premature Infants (Poppi) study: randomised placebo-controlled trial.

Pulse Oximeter Saturation Targeting and Oximeter Changes in the Benefits of Oxygen Saturation Targeting (BOOST)-II Australia and BOOST-II UK Oxygen Trials (2018)
Journal Article
Stenson, B. J., Donoghoe, M., Brocklehurst, P., Davis, P. G., Juszczak, E., Marschner, I. C., …Tarnow-Mordi, W. O. (2019). Pulse Oximeter Saturation Targeting and Oximeter Changes in the Benefits of Oxygen Saturation Targeting (BOOST)-II Australia and BOOST-II UK Oxygen Trials. Journal of Pediatrics, 204, 301-304.E2. https://doi.org/10.1016/j.jpeds.2018.08.033

Infants in the Australian and UK Benefits of Oxygen Saturation Targeting-II trials treated using revised oximeters spent more time within their planned pulse oximeter saturation target ranges than infants treated using the original oximeters (P

Association Between Oxygen Saturation Targeting and Death or Disability in Extremely Preterm Infants in the Neonatal Oxygenation Prospective Meta-analysis Collaboration (2018)
Journal Article
Askie, L. M., Darlow, B. A., Finer, N., Schmidt, B., Stenson, B., Tarnow-Mordi, W., …for the Neonatal Oxygenation Prospective Meta-analysis (NeOProM) Collaboration. (2018). Association Between Oxygen Saturation Targeting and Death or Disability in Extremely Preterm Infants in the Neonatal Oxygenation Prospective Meta-analysis Collaboration. Journal of the American Medical Association, 319(21), 2190–2201. https://doi.org/10.1001/jama.2018.5725

IMPORTANCE There are potential benefits and harms of hyperoxemia and hypoxemia for extremely preterm infants receiving more vs less supplemental oxygen. OBJECTIVE To compare the effects of different target ranges for oxygen saturation asmeasured b... Read More about Association Between Oxygen Saturation Targeting and Death or Disability in Extremely Preterm Infants in the Neonatal Oxygenation Prospective Meta-analysis Collaboration.