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Pulse Oximeter Saturation Targeting and Oximeter Changes in the Benefits of Oxygen Saturation Targeting (BOOST)-II Australia and BOOST-II UK Oxygen Trials

Stenson, Benjamin J.; Donoghoe, Mark; Brocklehurst, Peter; Davis, Peter G.; Juszczak, Edmund; Marschner, Ian C.; Simes, John; Tarnow-Mordi, William O.

Authors

Benjamin J. Stenson

Mark Donoghoe

Peter Brocklehurst

Peter G. Davis

Ian C. Marschner

John Simes

William O. Tarnow-Mordi



Abstract

Infants in the Australian and UK Benefits of Oxygen Saturation Targeting-II trials treated using revised oximeters spent more time within their planned pulse oximeter saturation target ranges than infants treated using the original oximeters (P < .001). This may explain the larger mortality difference seen with revised oximeters. If so, average treatment effects from the Neonatal Oxygen Prospective Meta-analysis trials may be underestimates.

Citation

Stenson, B. J., Donoghoe, M., Brocklehurst, P., Davis, P. G., Juszczak, E., Marschner, I. C., …Tarnow-Mordi, W. O. (2019). Pulse Oximeter Saturation Targeting and Oximeter Changes in the Benefits of Oxygen Saturation Targeting (BOOST)-II Australia and BOOST-II UK Oxygen Trials. Journal of Pediatrics, 204, 301-304.E2. https://doi.org/10.1016/j.jpeds.2018.08.033

Journal Article Type Article
Acceptance Date Aug 15, 2018
Online Publication Date Oct 9, 2018
Publication Date 2019-01
Deposit Date Feb 8, 2023
Journal The Journal of Pediatrics
Print ISSN 0022-3476
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 204
Pages 301-304.E2
DOI https://doi.org/10.1016/j.jpeds.2018.08.033
Keywords Pediatrics, Perinatology and Child Health
Public URL https://nottingham-repository.worktribe.com/output/16802173
Publisher URL https://www.jpeds.com/article/S0022-3476(18)31207-1/fulltext
Additional Information This article is maintained by: Elsevier; Article Title: Pulse Oximeter Saturation Targeting and Oximeter Changes in the Benefits of Oxygen Saturation Targeting (BOOST)-II Australia and BOOST-II UK Oxygen Trials; Journal Title: The Journal of Pediatrics; CrossRef DOI link to publisher maintained version: https://doi.org/10.1016/j.jpeds.2018.08.033; Content Type: article; Copyright: © 2018 Elsevier Inc. All rights reserved.