All Outputs (165)

Iron-catalyzed indolizine synthesis from pyridines, diazo compounds, and alkynes (2017)
Journal Article
Douglas, T., Pordea, A., & Dowden, J. (in press). Iron-catalyzed indolizine synthesis from pyridines, diazo compounds, and alkynes. Organic Letters, 19(23), https://doi.org/10.1021/acs.orglett.7b03252

The iron (III) catalyzed synthesis of indolizines from commercially available alkyne, pyridine, and diazo precursors is reported. This mild, expedient method is tolerant of various solvents and proceeds with as little as 0.25 mol % [Fe(TPP)Cl]. Signi... Read More about Iron-catalyzed indolizine synthesis from pyridines, diazo compounds, and alkynes.

Oxygen-rich microporous carbons with exceptional hydrogen storage capacity (2017)
Journal Article
Blankenship, T. S., Balahmar, N., & Mokaya, R. (in press). Oxygen-rich microporous carbons with exceptional hydrogen storage capacity. Nature Communications, 8, Article 1545. https://doi.org/10.1038/s41467-017-01633-x

Porous carbons have been extensively investigated for hydrogen storage but, to date, appear to have an upper limit to their storage capacity. Here, in an effort to circumvent this upper limit, we explore the potential of oxygen-rich activated carbons... Read More about Oxygen-rich microporous carbons with exceptional hydrogen storage capacity.

An On-Surface Reaction Confined within a Porous Molecular Template (2017)
Journal Article
Judd, C. J., Champness, N. R., & Saywell, A. (2018). An On-Surface Reaction Confined within a Porous Molecular Template. Chemistry - A European Journal, 24(1), 56-61. https://doi.org/10.1002/chem.201704693

On-surface reactions based on metal-catalysed Ullmann coupling have been successfully employed to synthesise a wide variety of covalently coupled structures. Substrate chemistry and topology are both known to effect the progression of an on-surface r... Read More about An On-Surface Reaction Confined within a Porous Molecular Template.

Click Chemistry: Mechanistic Insights into the Role of Amines Using Single-Molecule Spectroscopy (2017)
Journal Article
Wang, B., Lanterna, A. E., & Scaiano, J. C. (2017). Click Chemistry: Mechanistic Insights into the Role of Amines Using Single-Molecule Spectroscopy. ACS Catalysis, 7(12), 8487-8492. https://doi.org/10.1021/acscatal.7b03150

Single-molecule spectroscopy is used to gain insights into the click chemistry reaction photocatalyzed by copper. We show that CuxO@Nb2O5 catalysts can act as truly heterogeneous photocatalysts and that the amine plays an important role in the comple... Read More about Click Chemistry: Mechanistic Insights into the Role of Amines Using Single-Molecule Spectroscopy.

Supramolecular networks stabilise and functionalise black phosphorus (2017)
Journal Article
Korolkov, V. V., Timokhin, I. G., Haubrichs, R., Smith, E. F., Yang, L., Yang, S., …Beton, P. H. (2017). Supramolecular networks stabilise and functionalise black phosphorus. Nature Communications, 8(1), Article 1385. https://doi.org/10.1038/s41467-017-01797-6

© 2017 The Author(s). The limited stability of the surface of black phosphorus (BP) under atmospheric conditions is a significant constraint on the exploitation of this layered material and its few layer analogue, phosphorene, as an optoelectronic ma... Read More about Supramolecular networks stabilise and functionalise black phosphorus.

Thionated naphthalene diimides: tuneable chromophores for applications in photoactive dyads (2017)
Journal Article
Pearce, N., Davies, E. S., Horvath, R., Pfeiffer, C. R., Sun, X., Lewis, W., …Champness, N. R. (2018). Thionated naphthalene diimides: tuneable chromophores for applications in photoactive dyads. Physical Chemistry Chemical Physics, 20(2), https://doi.org/10.1039/c7cp06952a

Varying the degree of thionation of a series of naphthalene diimide (NDI) and naphthalic imides (NI) phenothiazine dyad systems afford a systematic approach for tuning of the system’s donor-acceptor energy gap. Each dyad was compared to model NDI/NI... Read More about Thionated naphthalene diimides: tuneable chromophores for applications in photoactive dyads.

NEXAFS spectroscopy of ionic liquids: experiments versus calculations (2017)
Journal Article
Fogarty, R. M., Matthews, R. P., Clough, M. T., Ashworth, C. R., Brandt, A., Corbett, P. J., …Lovelock, K. R. (in press). NEXAFS spectroscopy of ionic liquids: experiments versus calculations. Physical Chemistry Chemical Physics, https://doi.org/10.1039/C7CP07143D

Experimental near edge X–ray absorption fine structure (NEXAFS) spectra are reported for 12 ionic liquids (ILs) encompassing a range of chemical structures for both the sulfur 1s and nitrogen 1s edges and compared with time–dependent density function... Read More about NEXAFS spectroscopy of ionic liquids: experiments versus calculations.

Ullmann coupling reactions on Ag(111) and Ag(110); substrate influence on the formation of covalently coupled products and intermediate metal-organic structures Metal-Organic Structures (2017)
Journal Article
Judd, C. J., Haddow, S. L., Champness, N. R., & Saywell, A. (in press). Ullmann coupling reactions on Ag(111) and Ag(110); substrate influence on the formation of covalently coupled products and intermediate metal-organic structures Metal-Organic Structures. Scientific Reports, 7(14541), https://doi.org/10.1038/s41598-017-13315-1

On-surface reactions based on Ullmann coupling are known to proceed on coinage-metal substrates (e.g. Au, Ag, Cu), with the chemistry of the surface strongly influencing the reaction progression. In addition, the topography of the surface may be expe... Read More about Ullmann coupling reactions on Ag(111) and Ag(110); substrate influence on the formation of covalently coupled products and intermediate metal-organic structures Metal-Organic Structures.

Can a combination of poly(ethylene glycol) and dense phase carbon dioxide improve processing of polylactide? A high pressure rheology investigation (2017)
Journal Article
Pepper, K., Masson, T., De Focatiis, D. S., & Howdle, S. M. (in press). Can a combination of poly(ethylene glycol) and dense phase carbon dioxide improve processing of polylactide? A high pressure rheology investigation. Journal of Supercritical Fluids, 133(1), https://doi.org/10.1016/j.supflu.2017.10.014

High temperature melts or use of organic solvents are not practicable approaches for encapsulating protein based or thermally labile drugs into degradable polymers. Here, we demonstrate that poly(ethylene glycol) (PEG) in combination with supercritic... Read More about Can a combination of poly(ethylene glycol) and dense phase carbon dioxide improve processing of polylactide? A high pressure rheology investigation.

Enantioselective synthesis of 6,6-disubstituted pentafulvenes containing a chiral pendant hydroxy group (2017)
Journal Article
Nouch, R., Cini, M., Magre, M., Abid, M., Diéguez, M., Pàmies, O., …Lewis, W. (in press). Enantioselective synthesis of 6,6-disubstituted pentafulvenes containing a chiral pendant hydroxy group. Chemistry - A European Journal, https://doi.org/10.1002/chem.201704247

Simple enantioselective synthesis of 6,6-disubstituted pentafulvenes bearing chiral pendant hydroxy groups are attained by cascade reactivity using commercially available proline-based organocatalysts. Condensation of cyclopentadiene with the acetyl... Read More about Enantioselective synthesis of 6,6-disubstituted pentafulvenes containing a chiral pendant hydroxy group.

An experimental and theoretical study of the valence shell photoelectron spectra of 2-chloropyridine and 3-chloropyridine (2017)
Journal Article
Holland, D., Powis, I., Trofimov, A., Menzies, R., Potts, A., Karlsson, L., …Schirmer, J. (in press). An experimental and theoretical study of the valence shell photoelectron spectra of 2-chloropyridine and 3-chloropyridine. Journal of Chemical Physics, https://doi.org/10.1063/1.4999433

The valence shell photoelectron spectra of 2-chloropyridine and 3-chloropyridine have been studied both experimentally and theoretically. Synchrotron radiation has been employed to record angle resolved photoelectron spectra in the photon energy rang... Read More about An experimental and theoretical study of the valence shell photoelectron spectra of 2-chloropyridine and 3-chloropyridine.

Engineered, highly reactive substrates of microbial transglutaminase enable protein labeling within various secondary structure elements: Engineered, Highly Reactive Substrates of Microbial Transglutaminase (2017)
Journal Article
Rachel, N. M., Quaglia, D., Lévesque, É., Charette, A. B., & Pelletier, J. N. (2017). Engineered, highly reactive substrates of microbial transglutaminase enable protein labeling within various secondary structure elements: Engineered, Highly Reactive Substrates of Microbial Transglutaminase. Protein Science, 26(11), 2268-2279. https://doi.org/10.1002/pro.3286

Microbial transglutaminase (MTG) is a practical tool to enzymatically form isopeptide bonds between peptide or protein substrates. This natural approach to crosslinking the side?chains of reactive glutamine and lysine residues is solidly rooted in fo... Read More about Engineered, highly reactive substrates of microbial transglutaminase enable protein labeling within various secondary structure elements: Engineered, Highly Reactive Substrates of Microbial Transglutaminase.

Cigarette butt-derived carbons have ultra-high surface area and unprecedented hydrogen storage capacity (2017)
Journal Article
Blankenship, T. S., & Mokaya, R. (in press). Cigarette butt-derived carbons have ultra-high surface area and unprecedented hydrogen storage capacity. Energy and Environmental Science, https://doi.org/10.1039/C7EE02616A

Discarded cigarette filters, in the form of cigarette butts, are a major waste disposal and environmental pollution hazard due to mainly containing cellulose acetate which is nonbiodegradable; 5.8 trillion cigarettes are smoked worldwide per annum ge... Read More about Cigarette butt-derived carbons have ultra-high surface area and unprecedented hydrogen storage capacity.

Consistent assignment of the vibrations of symmetric and asymmetric ortho-disubstituted benzenes (2017)
Journal Article
Tuttle, W. D., Gardner, A. M., Andrejeva, A., Kemp, D., Wakefield, J. C., & Wright, T. G. (in press). Consistent assignment of the vibrations of symmetric and asymmetric ortho-disubstituted benzenes. Journal of Molecular Spectroscopy, 344, https://doi.org/10.1016/j.jms.2017.10.011

The form of molecular vibrations, and changes in these, give valuable insights into geometric and electronic structure upon electronic excitation or ionization, and within families of molecules. Here, we give a description of the phenyl-ring-localize... Read More about Consistent assignment of the vibrations of symmetric and asymmetric ortho-disubstituted benzenes.

Carbene Footprinting Reveals Binding Interfaces of a Multimeric Membrane-Spanning Protein (2017)
Journal Article
Manzi, L., Barrow, A. S., Hopper, J. T., Kaminska, R., Kleanthous, C., Robinson, C. V., …Oldham, N. J. (2017). Carbene Footprinting Reveals Binding Interfaces of a Multimeric Membrane-Spanning Protein. Angewandte Chemie International Edition, 56(47), 14873-14877. https://doi.org/10.1002/anie.201708254

© 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. Mapping the interaction sites between membrane-spanning proteins is a key challenge in structural biology. In this study a carbene-footprinting approach was developed and applied to identify the in... Read More about Carbene Footprinting Reveals Binding Interfaces of a Multimeric Membrane-Spanning Protein.

Structural and electronic determinants of lytic polysaccharide monooxygenase reactivity on polysaccharide substrates (2017)
Journal Article
Simmons, T. J., Frandsen, K. E. H., Ciano, L., Tryfona, T., Lenfant, N., Poulsen, J. C., …Dupree, P. (2017). Structural and electronic determinants of lytic polysaccharide monooxygenase reactivity on polysaccharide substrates. Nature Communications, 8(1), Article 1064. https://doi.org/10.1038/s41467-017-01247-3

Lytic polysaccharide monooxygenases (LPMOs) are industrially important copper-dependent enzymes that oxidatively cleave polysaccharides. Here we present a functional and structural characterization of two closely related AA9-family LPMOs from Lentinu... Read More about Structural and electronic determinants of lytic polysaccharide monooxygenase reactivity on polysaccharide substrates.

Thiol-Stabilized Gold Nanoparticles: New Ways To Displace Thiol Layers Using Yttrium or Lanthanide Chlorides (2017)
Journal Article
Vanegas, J. P., Scaiano, J. C., & Lanterna, A. E. (2017). Thiol-Stabilized Gold Nanoparticles: New Ways To Displace Thiol Layers Using Yttrium or Lanthanide Chlorides. Langmuir, 33(43), 12149-12154. https://doi.org/10.1021/acs.langmuir.7b01898

We use the aurophilic interactions shown by lanthanides to overcome the sulfur–gold interaction. UV–vis and X-ray photoelectron spectroscopy confirm that yttrium or lanthanide chlorides easily displace sulfur ligands from the surface of thiol-stabili... Read More about Thiol-Stabilized Gold Nanoparticles: New Ways To Displace Thiol Layers Using Yttrium or Lanthanide Chlorides.

Flow bioreactors as complementary tools for biocatalytic process intensification (2017)
Journal Article
Tamborini, L., Fernandes, P., Paradisi, F., & Molinari, F. (in press). Flow bioreactors as complementary tools for biocatalytic process intensification. Trends in Biotechnology, https://doi.org/10.1016/j.tibtech.2017.09.005

Biocatalysis has widened its scope and relevance since new molecular tools, including improved expression systems for proteins, protein and metabolic engineering, and rational techniques for immobilization, have become available. However, application... Read More about Flow bioreactors as complementary tools for biocatalytic process intensification.

Examining the role of protein structural dynamics in drug resistance in Mycobacterium tuberculosis (2017)
Journal Article
Shaw, D., Hill, R., Simpson, N., Husseini, F., Robb, K., Greetham, G. M., …Hunt, N. (in press). Examining the role of protein structural dynamics in drug resistance in Mycobacterium tuberculosis. Chemical Science, 8, https://doi.org/10.1039/C7SC03336B

Antimicrobial resistance represents a growing global health problem. The emergence of novel resistance mechanisms necessitates the development of alternative approaches to investigate the molecular fundamentals of resistance, leading ultimately to ne... Read More about Examining the role of protein structural dynamics in drug resistance in Mycobacterium tuberculosis.

The ESO Diffuse Interstellar Bands Large Exploration Survey EDIBLES: I. Project description, survey sample and quality assessment (2017)
Journal Article
Cox, N. L., Cami, J., Farhang, A., Smoker, J., Monreal-Ibero, A., Lallement, R., …Spaans, M. (in press). The ESO Diffuse Interstellar Bands Large Exploration Survey EDIBLES: I. Project description, survey sample and quality assessment. Astronomy and Astrophysics, 606, Article A76. https://doi.org/10.1051/0004-6361/201730912

The carriers of the diffuse interstellar bands (DIBs) are largely unidentified molecules ubiquitously present in the interstellar medium (ISM). After decades of study, two strong and possibly three weak near-infrared DIBs have recently been attribute... Read More about The ESO Diffuse Interstellar Bands Large Exploration Survey EDIBLES: I. Project description, survey sample and quality assessment.