All Outputs (38)

Burden of comorbidity in systemic lupus erythematosus in the UK, 1999–2012 (2016)
Journal Article
Rees, F., Doherty, M., Grainge, M., Lanyon, P., Davenport, G., & Zhang, W. (in press). Burden of comorbidity in systemic lupus erythematosus in the UK, 1999–2012. Arthritis Care and Research, 68(6), https://doi.org/10.1002/acr.22751

Objective: To estimate the comorbidity associated with systemic lupus erythematosus (SLE) in the UK during 1999–2012. Methods: A retrospective cohort study using the UK Clinical Practice Research Datalink was conducted. Prevalent cases of SLE wer... Read More about Burden of comorbidity in systemic lupus erythematosus in the UK, 1999–2012.

Transient receptor potential canonical 5 (TRPC5) protects against pain and vascular inflammation in arthritis and joint inflammation (2016)
Journal Article
Alawi, K. M., Russell, F. A., Aubdool, A. A., Srivastava, S., Riffo-Vasquez, Y., Baldissera, L., …Brain, S. D. (2017). Transient receptor potential canonical 5 (TRPC5) protects against pain and vascular inflammation in arthritis and joint inflammation. Annals of the Rheumatic Diseases, 76(1), 252-260. https://doi.org/10.1136/annrheumdis-2015-208886

Objective: Transient receptor potential canonical 5 (TRPC5) is functionally expressed on a range of cells including fibroblast-like synoviocytes, which play an important role in arthritis. A role for TRPC5 in inflammation has not been previously show... Read More about Transient receptor potential canonical 5 (TRPC5) protects against pain and vascular inflammation in arthritis and joint inflammation.

Selective inhibition of tropomyosin-receptor-kinase A (TrkA) reduces pain and joint damage in two rat models of inflammatory arthritis (2016)
Journal Article
Ashraf, S., Bouhana, K. S., Pheneger, J., Andrews, S. W., & Walsh, D. A. (2016). Selective inhibition of tropomyosin-receptor-kinase A (TrkA) reduces pain and joint damage in two rat models of inflammatory arthritis. Arthritis Research and Therapy, 18(1), https://doi.org/10.1186/s13075-016-0996-z

Background: Inflammation is an essential component of arthritis pain. Nerve growth factor (NGF) plays a key role in acute and chronic pain states especially those associated with inflammation. NGF acts through tropomyosin-receptor-kinase A (TrkA). NG... Read More about Selective inhibition of tropomyosin-receptor-kinase A (TrkA) reduces pain and joint damage in two rat models of inflammatory arthritis.

An amateur runner with hip pain and antalgic gait (2016)
Journal Article
Hughes, H. J. J., & Kluzek, S. (2016). An amateur runner with hip pain and antalgic gait. BMJ, 353, https://doi.org/10.1136/bmj.i2400

Erosive and osteoarthritic structural progression in early rheumatoid arthritis (2016)
Journal Article
McWilliams, D. F., Marshall, M., Jayakumar, K., Doherty, S., Doherty, M., Zhang, W., …Walsh, D. A. (2016). Erosive and osteoarthritic structural progression in early rheumatoid arthritis. Rheumatology, 55(8), 1477-1488. https://doi.org/10.1093/rheumatology/kew197

OBJECTIVES: To investigate factors associated with joint damage in early RA, and how comorbid OA might influence patient assessment and outcomes. METHODS: Baseline radiographs of hands and feet from 512 participants in the Early RA Network cohort, an... Read More about Erosive and osteoarthritic structural progression in early rheumatoid arthritis.

185?Identification of Clinical Phenotypes in Knee Osteoarthritis: A Systematic Review of the Literature (2016)
Journal Article
Dell’Isola, A., Allan, R., Louise, S. S., Marreiros, S. S., & Steultjens, M. (2016). 185 Identification of Clinical Phenotypes in Knee Osteoarthritis: A Systematic Review of the Literature. Rheumatology, 55(Issue suppl_1), i137. https://doi.org/10.1093/rheumatology/kew137.004

182?The Effects of Self-Reported Knee Joint Instability on Muscle Co-Activation in Osteoarthritis of the Knee (2016)
Journal Article
Smith, S., Woodburn, J., & Steultjens, M. P. M. (2016). 182?The Effects of Self-Reported Knee Joint Instability on Muscle Co-Activation in Osteoarthritis of the Knee. Rheumatology, 55(suppl_1), i136. https://doi.org/10.1093/rheumatology/kew137.001

Electromechanical delay and rate of force development in individuals with knee osteoarthritis (2016)
Journal Article
Smith, S., Woodburn, J., & Steultjens, M. (2016). Electromechanical delay and rate of force development in individuals with knee osteoarthritis. Osteoarthritis and Cartilage, 24(Supplement 1), S122. https://doi.org/10.1016/j.joca.2016.01.239

Suprapatellar synovial hypertrophy and reliability of the novel ultrasound assessment of suprapatellar recess in patients with recent knee injuries or early osteoarthritis (2016)
Journal Article
Kluzek, S., Wedatilake, T., McNally, E., Price, A., Judge, A., Watt, F., …Newton, J. (2016). Suprapatellar synovial hypertrophy and reliability of the novel ultrasound assessment of suprapatellar recess in patients with recent knee injuries or early osteoarthritis. Osteoarthritis and Cartilage, 24(S1), S299-S300. https://doi.org/10.1016/j.joca.2016.01.545

Purpose: Early through to late stage knee osteoarthritis (KOA) has been linked with effusion-synovitis in the suprapatellar pouch and chronic inflammation has been particularly associated with pain. Recent studies also suggest that synovial hypertrop... Read More about Suprapatellar synovial hypertrophy and reliability of the novel ultrasound assessment of suprapatellar recess in patients with recent knee injuries or early osteoarthritis.

The measurement of psychological constructs in people with osteoarthritis of the knee: a psychometric evaluation (2016)
Journal Article
Lincoln, N., Moreton, B., Turner, K., & Walsh, D. A. (2017). The measurement of psychological constructs in people with osteoarthritis of the knee: a psychometric evaluation. Disability and Rehabilitation, 39(4), https://doi.org/10.3109/09638288.2016.1146356

Purpose: To examine the measurement properties of measures of psychological constructs in people with knee osteoarthritis. Method: Participants with osteoarthritis of the knee completed the beck depression inventory (BDI-II), state-trait anxiety inv... Read More about The measurement of psychological constructs in people with osteoarthritis of the knee: a psychometric evaluation.

Synovial changes detected by ultrasound in people with knee osteoarthritis – a meta-analysis of observational studies (2016)
Journal Article
Sarmanov, A., Hall, M. C., Moses, J., Doherty, M., & Zhang, W. (2016). Synovial changes detected by ultrasound in people with knee osteoarthritis – a meta-analysis of observational studies. Osteoarthritis and Cartilage, 24(8), 1376-1383. https://doi.org/10.1016/j.joca.2016.03.004

© 2016 The Authors Objectives To examine the prevalence of synovial effusion, synovial hypertrophy and positive Doppler signal (DS) detected by ultrasound (US) in people with knee osteoarthritis (OA) and/or knee pain compared to that in the general p... Read More about Synovial changes detected by ultrasound in people with knee osteoarthritis – a meta-analysis of observational studies.

Low omega-3 fatty acid levels associate with frequent gout attacks: a case control study (2016)
Journal Article
Abhishek, A., Valdes, A. M., & Doherty, M. (in press). Low omega-3 fatty acid levels associate with frequent gout attacks: a case control study. Annals of the Rheumatic Diseases, 75(4), https://doi.org/10.1136/annrheumdis-2015-208767

Hydrolysed formula and risk of allergic or autoimmune disease: Systematic review and meta-analysis (2016)
Journal Article
Boyle, R. J., Ierodiakonou, D., Khan, T., Chivinge, J., Robinson, Z., Geoghegan, N., …Leonardi-Bee, J. (2016). Hydrolysed formula and risk of allergic or autoimmune disease: Systematic review and meta-analysis. BMJ, 352, Article i974. https://doi.org/10.1136/bmj.i974

© BMJ Publishing Group Ltd 2016. Objective To determine whether feeding infants with hydrolysed formula reduces their risk of allergic or autoimmune disease. Design Systematic review and meta-analysis, as part of a series of systematic reviews commis... Read More about Hydrolysed formula and risk of allergic or autoimmune disease: Systematic review and meta-analysis.

The epidemiology of childhood psoriasis: a scoping review (2016)
Journal Article
Burden-Teh, E., Thomas, K. S., Ratib, S., Grindlay, D. J., Adaji, E., & Murphy, R. (2016). The epidemiology of childhood psoriasis: a scoping review. British Journal of Dermatology, 174(6), 1242-1257. https://doi.org/10.1111/bjd.14507

Psoriasis is an inflammatory noncommunicable skin disease that affects both adults and children. At present, the epidemiology and natural history of psoriasis are not widely understood. This scoping review aimed to map the existing literature on the... Read More about The epidemiology of childhood psoriasis: a scoping review.

Response to: ‘Painful knee but not hand osteoarthritis is an independent predictor of mortality over 23 years follow-up of a population-based cohort of middle-aged women’ by Gao et al (2016)
Journal Article
Kluzek, S., Sanchez-Santos, M. T., Leyland, K. M., Judge, A., Newton, J., & Arden, N. K. (2016). Response to: ‘Painful knee but not hand osteoarthritis is an independent predictor of mortality over 23 years follow-up of a population-based cohort of middle-aged women’ by Gao et al. Annals of the Rheumatic Diseases, 75(4), Article e23. https://doi.org/10.1136/annrheumdis-2015-209029

Home-administered pre-surgical psychological intervention for knee osteoarthritis (HAPPiKNEES): study protocol for a randomised controlled trial (2016)
Journal Article
das Nair, R., Anderson, P., Clarke, S. P., Leighton, P., Lincoln, N., Mhizha-Murira, J. R., …Walsh, D. A. (2016). Home-administered pre-surgical psychological intervention for knee osteoarthritis (HAPPiKNEES): study protocol for a randomised controlled trial. Trials, 17(54), 1-11. https://doi.org/10.1186/s13063-016-1165-z

Background: Knee replacement surgery reduces pain for many people with osteoarthritis (OA). However, surgical outcomes are partly dependent on patients’ moods, and those with depression or anxiety have worse outcomes. Approximately one-third of peopl... Read More about Home-administered pre-surgical psychological intervention for knee osteoarthritis (HAPPiKNEES): study protocol for a randomised controlled trial.

Simple advice for a simple ankle sprain?: the not so benign ankle injury (2016)
Journal Article
Palmer-Green, D. S., Batt, M. E., & Scammell, B. E. (2016). Simple advice for a simple ankle sprain?: the not so benign ankle injury. Osteoarthritis and Cartilage, 24(6), https://doi.org/10.1016/j.joca.2015.12.019

Mortality in systemic lupus erythematosus in the United Kingdom 1999-2012 (2016)
Journal Article
Rees, F., Doherty, M., Grainge, M. J., Lanyon, P., Davenport, G., & Zhang, W. (2016). Mortality in systemic lupus erythematosus in the United Kingdom 1999-2012. Rheumatology, 55(5), 854-860. https://doi.org/10.1093/rheumatology/kev424

OBJECTIVES: To estimate the mortality associated with SLE during the period 1999-2012 by age, gender and region; and to ascertain the cause of death for people with SLE. METHODS: A retrospective cohort study using the UK Clinical Practice Research... Read More about Mortality in systemic lupus erythematosus in the United Kingdom 1999-2012.