All Outputs (2)

Dynamic regulation of auxin oxidase and conjugating enzymes AtDAO1 and GH3 modulates auxin homeostasis (2016)
Journal Article
Mellor, N. L., Band, L. R., Pěnčík, A., Novak, O., Rashed, A., Holman, T., …Owen, M. R. (2016). Dynamic regulation of auxin oxidase and conjugating enzymes AtDAO1 and GH3 modulates auxin homeostasis. Proceedings of the National Academy of Sciences, 113(39), 11022-11027. https://doi.org/10.1073/pnas.1604458113

Auxin is a key hormone regulating plant growth and development. We combine experiments and mathematical modeling to reveal how auxin levels are maintained via feedback regulation of genes encoding key metabolic enzymes. We describe how regulation of... Read More about Dynamic regulation of auxin oxidase and conjugating enzymes AtDAO1 and GH3 modulates auxin homeostasis.

The spatiotemporal order of signaling events unveils the logic of development signaling (2016)
Journal Article
Zhu, H., Owen, M. R., & Mao, Y. (in press). The spatiotemporal order of signaling events unveils the logic of development signaling. Bioinformatics, 32(15), https://doi.org/10.1093/bioinformatics/btw121

Motivation: Animals from worms and insects to birds and mammals show distinct body plans; however, the embryonic development of diverse body plans with tissues and organs within is controlled by a surprisingly few signaling pathways. It is well recog... Read More about The spatiotemporal order of signaling events unveils the logic of development signaling.